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Compile Data Set for Download or QSAR

Found 1 hit of kd data for polymerid = 5662   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melatonin receptor type 1B


(Homo sapiens (Human))		BDBM50528405
PNG
(CHEMBL4449712)
Show SMILES Nc1nc(NCc2ccc(Oc3ccccc3)cc2)nc(n1)-c1c(F)cccc1CO
Show InChI InChI=1S/C23H20FN5O2/c24-19-8-4-5-16(14-30)20(19)21-27-22(25)29-23(28-21)26-13-15-9-11-18(12-10-15)31-17-6-2-1-3-7-17/h1-12,30H,13-14H2,(H3,25,26,27,28,29)
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.10E+3n/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Agonist activity at human MT2 receptor expressed in HTLA cells assessed as stimulation of beta-arrestin recruitment incubated for 16 to 20 hrs by bri...

J Med Chem 62: 7557-7574 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00869
BindingDB Entry DOI: 10.7270/Q22N55Q5
More data for this
Ligand-Target Pair