BindingDB PrimarySearch

Found 11 hits of kd data for polymerid = 6845
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50522839 (CHEMBL2095003 \| DNDI1417825) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a
Huazhong Agricultural University Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...				Bioorg Med Chem 27: 3229-3236 (2019) Article DOI: 10.1016/j.bmc.2019.05.040 BindingDB Entry DOI: 10.7270/Q2571GFK
Huazhong Agricultural University Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50068270 ((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a
Guizhou Medcial University Curated by ChEMBL					Assay Description Binding affinity to IDH1 R132C mutant (unknown origin) by surface plasmon resonance assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126825 BindingDB Entry DOI: 10.7270/Q2P55S1D
Guizhou Medcial University Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50522839 (CHEMBL2095003 \| DNDI1417825) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a
Huazhong Agricultural University Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...				Bioorg Med Chem 27: 3229-3236 (2019) Article DOI: 10.1016/j.bmc.2019.05.040 BindingDB Entry DOI: 10.7270/Q2571GFK
Huazhong Agricultural University Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50111796 (CHEMBL3605384) Show SMILES O=C1NC(=S)N\C1=C\c1ccc(=O)[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in absence of NAD...				J Med Chem 58: 6899-908 (2015) Article DOI: 10.1021/acs.jmedchem.5b00684 BindingDB Entry DOI: 10.7270/Q2M61N2D
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50111796 (CHEMBL3605384) Show SMILES O=C1NC(=S)N\C1=C\c1ccc(=O)[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in presence of NA...				J Med Chem 58: 6899-908 (2015) Article DOI: 10.1021/acs.jmedchem.5b00684 BindingDB Entry DOI: 10.7270/Q2M61N2D
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50068270 ((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a
Guizhou Medcial University Curated by ChEMBL					Assay Description Binding affinity to IDH1 R132H mutant (unknown origin) by surface plasmon resonance assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126825 BindingDB Entry DOI: 10.7270/Q2P55S1D
Guizhou Medcial University Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50557557 (CHEMBL504910) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to C-terminal His6-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 20 mins by Red-N...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116095 BindingDB Entry DOI: 10.7270/Q20Z76ZZ
TBA					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50378034 (CHEMBL504404 \| NSC-287088 \| PHYSALIN B) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.53E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to C-terminal His6-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 20 mins by Red-N...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116095 BindingDB Entry DOI: 10.7270/Q20Z76ZZ
TBA					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50111796 (CHEMBL3605384) Show SMILES O=C1NC(=S)N\C1=C\c1ccc(=O)[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in presence of NA...				J Med Chem 58: 6899-908 (2015) Article DOI: 10.1021/acs.jmedchem.5b00684 BindingDB Entry DOI: 10.7270/Q2M61N2D
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50522839 (CHEMBL2095003 \| DNDI1417825) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a
Huazhong Agricultural University Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by ...				Bioorg Med Chem 27: 3229-3236 (2019) Article DOI: 10.1016/j.bmc.2019.05.040 BindingDB Entry DOI: 10.7270/Q2571GFK
Huazhong Agricultural University Curated by ChEMBL					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50068270 ((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a
Guizhou Medcial University Curated by ChEMBL					Assay Description Binding affinity to IDH1 (unknown origin) by surface plasmon resonance assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126825 BindingDB Entry DOI: 10.7270/Q2P55S1D
Guizhou Medcial University Curated by ChEMBL					More data for this Ligand-Target Pair