BindingDB PrimarySearch

Found 8 hits of kd data for polymerid = 9627
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM552953 (N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM553008 (N-(5-(2- morpholinopyrimidin-5- yl)-2-((3R,5S)-3,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM553032 (N-[4-chloro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM553011 (N-[4-methyl-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM553005 (N-[4-methoxy-5-(2- morpholin-4- ylpyrimidin-5-yl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated MLL1 (1566 to 1784 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry met...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM553009 (N-[5-(2-morpholin-4- ylpyrimidin-5-yl)-2-[rac- (3R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20� C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM50282115 (CHEMBL4165111) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Binding affinity to 15N-labeled GST-tagged MLL1 PHD3 finger domain (1565 to 1627 residues) (unknown origin) expressed in Escherichia coli Rosetta2 BL...				Eur J Med Chem 136: 14-35 (2017) Article DOI: 10.1016/j.ejmech.2017.04.047 BindingDB Entry DOI: 10.7270/Q2F76G3G
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair