Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein phosphatase 10 (Homo sapiens (Human)) | BDBM50250606 (CHEMBL4077342) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho... | J Med Chem 60: 9299-9319 (2017) Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 10 (Homo sapiens (Human)) | BDBM50441298 (CHEMBL2431708) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysis | J Med Chem 56: 7636-50 (2013) Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 10 (Homo sapiens (Human)) | BDBM50441297 (CHEMBL2431664 | CHEMBL2431666) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysis | J Med Chem 56: 7636-50 (2013) Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 10 (Homo sapiens (Human)) | BDBM50441296 (CHEMBL2431665 | CHEMBL2431667) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysis | J Med Chem 56: 7636-50 (2013) Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW | |||||||||||
More data for this Ligand-Target Pair |