Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-galactosidase (Homo sapiens (Human)) | BDBM50254109 (CHEMBL4069909) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Competitive inhibition of human fibroblast lysosomal beta-galactosidase using 4-methylumbelliferyl-beta-D-galactopyranoside as substrate pre-incubate... | Bioorg Med Chem Lett 27: 3431-3435 (2017) Article DOI: 10.1016/j.bmcl.2017.05.086 BindingDB Entry DOI: 10.7270/Q29889D9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ... | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50358321 (CHEMBL1922579 | CHEMBL1922581) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amicus Therapeutics Curated by ChEMBL | Assay Description Inhibition of human beta galactosidase | J Med Chem 56: 2705-25 (2013) Article DOI: 10.1021/jm301557k BindingDB Entry DOI: 10.7270/Q26111N4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50358321 (CHEMBL1922579 | CHEMBL1922581) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Competitive inhibition of human fibroblast lysosomal beta-galactosidase using 4-methylumbelliferyl-beta-D-galactopyranoside as substrate pre-incubate... | Bioorg Med Chem Lett 27: 3431-3435 (2017) Article DOI: 10.1016/j.bmcl.2017.05.086 BindingDB Entry DOI: 10.7270/Q29889D9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50246569 (CHEMBL505422 | Methyl 6-[N2-dansyl-N6-(1,5-dideoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ... | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50356097 (CHEMBL461161) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ... | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50356096 (CHEMBL1911831) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ... | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50403936 (CHEMBL2114148) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla Curated by ChEMBL | Assay Description Inhibition constant against Beta-galactosidase from Jack beans; Mixed (Non competitive and competitive) | Bioorg Med Chem Lett 12: 2335-9 (2002) BindingDB Entry DOI: 10.7270/Q2GB23CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50403936 (CHEMBL2114148) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla Curated by ChEMBL | Assay Description Inhibitor concentration of the compound against alpha-L-Fucosidase from Bovine epididymis | Bioorg Med Chem Lett 12: 2335-9 (2002) BindingDB Entry DOI: 10.7270/Q2GB23CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50075942 (CHEMBL165192 | N-[2,5-Dihydroxy-6-hydroxymethyl-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de chimie organique de l'Université de Lausanne Curated by ChEMBL | Assay Description Inhibition constant of the compound against beta-galactosidase enzyme of jack bean was reported | Bioorg Med Chem Lett 9: 793-6 (1999) BindingDB Entry DOI: 10.7270/Q2K073FM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50254118 (CHEMBL4090899) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Competitive inhibition of human fibroblast lysosomal beta-galactosidase using 4-methylumbelliferyl-beta-D-galactopyranoside as substrate pre-incubate... | Bioorg Med Chem Lett 27: 3431-3435 (2017) Article DOI: 10.1016/j.bmcl.2017.05.086 BindingDB Entry DOI: 10.7270/Q29889D9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50403937 (CHEMBL2114149) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla Curated by ChEMBL | Assay Description Inhibition constant (Competitive) of the compound against Beta-galactosidasee from Aspergillus niger was tested at a dose of 1 mM | Bioorg Med Chem Lett 12: 2335-9 (2002) BindingDB Entry DOI: 10.7270/Q2GB23CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50104296 (2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Section de Chimie de l'Universit£ de Lausanne Curated by ChEMBL | Assay Description Inhibitory activity towards Beta-galactosidase from Jack bean | Bioorg Med Chem Lett 11: 2489-93 (2001) BindingDB Entry DOI: 10.7270/Q2H70GBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50073992 (((3aS,4aS,7aS,7bR)-6,6-Dimethyl-3a,4a,7a,7b-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de chimie organique de l'Université de Lausanne Curated by ChEMBL | Assay Description Inhibition of beta-glucosidase from Caldocellum saccharolyticum | Bioorg Med Chem Lett 9: 277-8 (1999) BindingDB Entry DOI: 10.7270/Q28051T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50298560 (1-(beta-D-galactopyranosyl)-4-phenyl-1,2,3-triazol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Katholieke Universiteit Leuven Curated by ChEMBL | Assay Description Inhibition of beta-galactosidase | Bioorg Med Chem 17: 5117-25 (2009) Article DOI: 10.1016/j.bmc.2009.05.056 BindingDB Entry DOI: 10.7270/Q2ZW1M03 | |||||||||||
More data for this Ligand-Target Pair |