Found 5 hits of ki data for polymerid = 50001122,50005655 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Creatine kinase M-type
(Oryctolagus cuniculus) | BDBM50370908
(CHEMBL373782)Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)c1ccccc1 Show InChI InChI=1S/C25H17NO5/c27-23(17-4-2-1-3-5-17)18-10-12-20(13-11-18)26-24(28)19-8-6-16(7-9-19)21-14-15-22(31-21)25(29)30/h1-15H,(H,26,28)(H,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1
Curated by ChEMBL
| Assay Description Inhibition of rabbit muscle creatine kinase by pH-stat assay |
J Med Chem 50: 1865-75 (2007)
Article DOI: 10.1021/jm061460r BindingDB Entry DOI: 10.7270/Q2HT2Q3B |
More data for this Ligand-Target Pair | |
Creatine kinase M-type
(Oryctolagus cuniculus) | BDBM50370908
(CHEMBL373782)Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)c1ccccc1 Show InChI InChI=1S/C25H17NO5/c27-23(17-4-2-1-3-5-17)18-10-12-20(13-11-18)26-24(28)19-8-6-16(7-9-19)21-14-15-22(31-21)25(29)30/h1-15H,(H,26,28)(H,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1
Curated by ChEMBL
| Assay Description Inhibition of rabbit muscle creatine kinase-MgATP complex by pH-stat assay |
J Med Chem 50: 1865-75 (2007)
Article DOI: 10.1021/jm061460r BindingDB Entry DOI: 10.7270/Q2HT2Q3B |
More data for this Ligand-Target Pair | |
Creatine kinase M-type
(Homo sapiens (Human)) | BDBM50291548
(CHEMBL8056 | Phosphocreatine analogue)Show InChI InChI=1S/C5H11N2O5P/c1-7(2-5(8)9)4(6)3-13(10,11)12/h6H,2-3H2,1H3,(H,8,9)(H2,10,11,12)/p-2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 1.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for inhibition against Creatine kinase (CK) |
Bioorg Med Chem Lett 7: 1021-1026 (1997)
Article DOI: 10.1016/S0960-894X(97)00161-3 BindingDB Entry DOI: 10.7270/Q2WW7HPG |
More data for this Ligand-Target Pair | |
Creatine kinase M-type
(Homo sapiens (Human)) | BDBM50291549
(CHEMBL8265 | Phosphocreatine analogue)Show InChI InChI=1S/C4H9N2O5P/c5-3(2-12(9,10)11)6-1-4(7)8/h1-2H2,(H2,5,6)(H,7,8)(H2,9,10,11)/p-2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 5.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for inhibition against Creatine kinase(CK) |
Bioorg Med Chem Lett 7: 1021-1026 (1997)
Article DOI: 10.1016/S0960-894X(97)00161-3 BindingDB Entry DOI: 10.7270/Q2WW7HPG |
More data for this Ligand-Target Pair | |
Creatine kinase M-type
(Homo sapiens (Human)) | BDBM50291547
(CHEMBL8013 | Phosphocreatine analogue)Show InChI InChI=1S/C5H11N2O5P/c6-4(3-13(10,11)12)7-2-1-5(8)9/h1-3H2,(H2,6,7)(H,8,9)(H2,10,11,12)/p-2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| 3.70E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for inhibition against Creatine kinase (CK) |
Bioorg Med Chem Lett 7: 1021-1026 (1997)
Article DOI: 10.1016/S0960-894X(97)00161-3 BindingDB Entry DOI: 10.7270/Q2WW7HPG |
More data for this Ligand-Target Pair | |