Compile Data Set for Download or QSAR

Found 14 hits of ki data for polymerid = 50004217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010993 (CHEMBL3265177) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nsc(=O)o1 Show InChI InChI=1S/C8H4N2O4S/c11-8-14-7(9-15-8)5-2-1-3-6(4-5)10(12)13/h1-4H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010988 (CHEMBL3259882) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)-c1nsc(=O)o1 |r| Show InChI InChI=1S/C19H17N3O4S/c1-12(23)20-16(11-13-5-3-2-4-6-13)17(24)21-15-9-7-14(8-10-15)18-22-27-19(25)26-18/h2-10,16H,11H2,1H3,(H,20,23)(H,21,24)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010986 (CHEMBL2336253) Show SMILES Cc1sc(cc1[N+]([O-])=O)-c1nsc(=O)o1 Show InChI InChI=1S/C7H4N2O4S2/c1-3-4(9(11)12)2-5(14-3)6-8-15-7(10)13-6/h2H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010995 (CHEMBL3265180) Show SMILES O=c1oc(ns1)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C10H6N2O2S/c13-10-14-9(12-15-10)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010997 (CHEMBL3265182) Show SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)-c1nsc(=O)o1 Show InChI InChI=1S/C13H14N2O4S/c1-13(2,3)19-11(16)14-9-6-4-8(5-7-9)10-15-20-12(17)18-10/h4-7H,1-3H3,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50011003 (CHEMBL3259879) Show SMILES O=c1oc(ns1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C13H14N2O3S/c16-13-18-12(14-19-13)11-3-1-2-10(8-11)9-15-4-6-17-7-5-15/h1-3,8H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010999 (CHEMBL3259876) Show SMILES O=c1oc(ns1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C14H9NO2S/c16-14-17-13(15-18-14)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50011001 (CHEMBL3259877) Show SMILES Oc1cc(cc(O)c1O)-c1nsc(=O)o1 Show InChI InChI=1S/C8H5NO5S/c10-4-1-3(2-5(11)6(4)12)7-9-15-8(13)14-7/h1-2,10-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010996 (CHEMBL3265181) Show SMILES FC(F)(F)c1ccccc1-c1nsc(=O)o1 Show InChI InChI=1S/C9H4F3NO2S/c10-9(11,12)6-4-2-1-3-5(6)7-13-16-8(14)15-7/h1-4H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010994 (CHEMBL3265178) Show SMILES O=c1oc(ns1)-c1ccccn1 Show InChI InChI=1S/C7H4N2O2S/c10-7-11-6(9-12-7)5-3-1-2-4-8-5/h1-4H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010987 (CHEMBL3259880) Show SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)-c1nsc(=O)o1 |r| Show InChI InChI=1S/C19H17N3O4S/c1-12(23)20-16(11-13-5-3-2-4-6-13)17(24)21-15-9-7-14(8-10-15)18-22-27-19(25)26-18/h2-10,16H,11H2,1H3,(H,20,23)(H,21,24)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50010991 (CHEMBL3259884) Show SMILES [N-]=[N+]=Nc1ccc(cc1)-c1nsc(=O)o1 Show InChI InChI=1S/C8H4N4O2S/c9-12-10-6-3-1-5(2-4-6)7-11-15-8(13)14-7/h1-4H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50011002 (CHEMBL3259878) Show SMILES O=c1oc(ns1)-c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C14H9NO2S/c16-14-17-13(15-18-14)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50332796 (5-phenyl-1,3,4-oxathiazol-2-one | CHEMBL1632533) Show SMILES O=c1oc(ns1)-c1ccccc1 Show InChI InChI=1S/C8H5NO2S/c10-8-11-7(9-12-8)6-4-2-1-3-5-6/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair