Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50124906 (CHEMBL3623776) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queensland University of Technology Curated by ChEMBL | Assay Description Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method | J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50125021 (CHEMBL3623779) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queensland University of Technology Curated by ChEMBL | Assay Description Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method | J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154254 (CHEMBL3775705) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154253 (CHEMBL3775377) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154252 (CHEMBL3774934) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113060 (US9695194, 1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 200 | -39.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446220 (CHEMBL3109164) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50125044 (CHEMBL3623790) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 362 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queensland University of Technology Curated by ChEMBL | Assay Description Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method | J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446221 (CHEMBL3109163) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113069 (US9695194, 5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 500 | -37.4 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113299 (US9695194, 15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 500 | -37.4 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113065 (US9695194, 2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 500 | -37.4 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113296 (US9695194, 13) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 600 | -36.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113297 (US9695194, 14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 600 | -36.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113067 (US9695194, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 600 | -36.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446218 (CHEMBL3109166) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446219 (CHEMBL3109165) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113300 (US9695194, 16) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113295 (US9695194, 12) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113283 (US9695194, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113119 (US9695194, 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113301 (US9695194, 17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113068 (US9695194, 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.30E+3 | -34.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446228 (CHEMBL3109061) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113293 (US9695194, 10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.90E+3 | -34.0 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113248 (US9695194, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 2.20E+3 | -33.6 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446224 (CHEMBL3109160) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446211 (CHEMBL3109058) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446229 (CHEMBL3109060) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM32709 ((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysis | Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50289001 (2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.50E+3 | -31.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113294 (US9695194, 11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | >1.00E+4 | >-29.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50167828 (CHEMBL3798972) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein-5 | Eur J Med Chem 116: 290-317 (2016) Article DOI: 10.1016/j.ejmech.2016.03.025 BindingDB Entry DOI: 10.7270/Q2NZ89HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein-5 | Eur J Med Chem 116: 290-317 (2016) Article DOI: 10.1016/j.ejmech.2016.03.025 BindingDB Entry DOI: 10.7270/Q2NZ89HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355088 (CHEMBL1834754) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446215 (CHEMBL3109169) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446214 (CHEMBL3109170) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355087 (CHEMBL1833982) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50125028 (CHEMBL3623791) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queensland University of Technology Curated by ChEMBL | Assay Description Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method | J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50391078 (CHEMBL2087346) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis | Bioorg Med Chem Lett 22: 6072-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.047 BindingDB Entry DOI: 10.7270/Q2SF2X8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50446227 (CHEMBL3109056) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do ABC Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ... | ACS Med Chem Lett 5: 128-32 (2014) Article DOI: 10.1021/ml4003698 BindingDB Entry DOI: 10.7270/Q2W37XSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50391075 (CHEMBL2087343) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis | Bioorg Med Chem Lett 22: 6072-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.047 BindingDB Entry DOI: 10.7270/Q2SF2X8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50391079 (CHEMBL2087347) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis | Bioorg Med Chem Lett 22: 6072-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.047 BindingDB Entry DOI: 10.7270/Q2SF2X8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50444597 (CHEMBL3099882) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Eur J Med Chem 70: 661-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.040 BindingDB Entry DOI: 10.7270/Q21837Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50444602 (CHEMBL3099874) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Eur J Med Chem 70: 661-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.040 BindingDB Entry DOI: 10.7270/Q21837Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50444603 (CHEMBL3099871) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Eur J Med Chem 70: 661-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.040 BindingDB Entry DOI: 10.7270/Q21837Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50444604 (CHEMBL3099870) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Eur J Med Chem 70: 661-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.040 BindingDB Entry DOI: 10.7270/Q21837Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50444598 (CHEMBL3099878) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 1.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis | Eur J Med Chem 70: 661-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.040 BindingDB Entry DOI: 10.7270/Q21837Z8 | |||||||||||
More data for this Ligand-Target Pair |
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