Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine racemase (Mus musculus) | BDBM50038343 (CHEMBL3360546) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Inhibition of mouse serine racemase by Lineweaver-Burk plot | Eur J Med Chem 89: 189-97 (2014) Article DOI: 10.1016/j.ejmech.2014.10.043 BindingDB Entry DOI: 10.7270/Q22N53WK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM14673 (Fragment 3 | Malonic Acid | propanedioic acid) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Inhibition of mouse serine racemase by Lineweaver-Burk plot | Eur J Med Chem 89: 189-97 (2014) Article DOI: 10.1016/j.ejmech.2014.10.043 BindingDB Entry DOI: 10.7270/Q22N53WK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM50378533 (CHEMBL568192) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse recombinant serine racemase transfected in bacterial expression system | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM14673 (Fragment 3 | Malonic Acid | propanedioic acid) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse recombinant serine racemase transfected in bacterial expression system | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM50378532 (CHEMBL569435) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by Linewaver-bur... | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM50378534 (CHEMBL216796) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 1.64E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse recombinant serine racemase transfected in bacterial expression system | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM50129194 ((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse brain serine racemase | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Schizosaccharomyces pombe (strain 972 / ATCC 24843...) | BDBM50444848 (CHEMBL3099359) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.67E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalhousie University Curated by ChEMBL | Assay Description Mixed type inhibition of N-terminal 6xHis-tagged recombinant Schizosaccharomyces pombe 972 serine racemase expressed in Escherichia coli BL21(DE3) us... | Bioorg Med Chem Lett 24: 390-3 (2013) Article DOI: 10.1016/j.bmcl.2013.10.061 BindingDB Entry DOI: 10.7270/Q2PV6MVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Schizosaccharomyces pombe (strain 972 / ATCC 24843...) | BDBM50444848 (CHEMBL3099359) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.61E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalhousie University Curated by ChEMBL | Assay Description Mixed type inhibition of N-terminal 6xHis-tagged recombinant Schizosaccharomyces pombe 972 serine racemase expressed in Escherichia coli BL21(DE3) us... | Bioorg Med Chem Lett 24: 390-3 (2013) Article DOI: 10.1016/j.bmcl.2013.10.061 BindingDB Entry DOI: 10.7270/Q2PV6MVC | |||||||||||
More data for this Ligand-Target Pair |