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Compile Data Set for Download or QSAR

Found 2 hits of ki data for polymerid = 50006297   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-binding cassette sub-family C member 4


(Homo sapiens (Human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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Article
PubMed
4.00E+3n/an/an/an/an/an/an/an/a



Radboud University Nijmegen Medical Centre

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot


Drug Metab Dispos 39: 1294-302 (2011)


Article DOI: 10.1124/dmd.110.037812
BindingDB Entry DOI: 10.7270/Q2MK6FMS
More data for this
Ligand-Target Pair
ATP-binding cassette sub-family C member 4


(Homo sapiens (Human))
BDBM50172903
PNG
(3,4-diarylpyrazoline derivative | CHEMBL364300)
Show SMILES CCN(C)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1 |w:9.9,c:14|
Show InChI InChI=1S/C20H24ClN5O2S/c1-4-25(3)29(27,28)24-20(22-2)26-14-18(15-8-6-5-7-9-15)19(23-26)16-10-12-17(21)13-11-16/h5-13,18H,4,14H2,1-3H3,(H,22,24)
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PC cid
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UniChem

Similars

Article
PubMed
7.00E+3n/an/an/an/an/an/an/an/a



Radboud University Nijmegen Medical Centre

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot


Drug Metab Dispos 39: 1294-302 (2011)


Article DOI: 10.1124/dmd.110.037812
BindingDB Entry DOI: 10.7270/Q2MK6FMS
More data for this
Ligand-Target Pair