Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-mannosidase (Canavalia ensiformis) | BDBM50579647 (CHEMBL5090920) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Jack bean alpha-mannosidase by Lineweaver-Burk plot | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00036 BindingDB Entry DOI: 10.7270/Q28G8QK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50124579 (CHEMBL3621532) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Savitribai Phule Pune University (formerly University of Pune) Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrate | J Med Chem 58: 7820-32 (2015) Article DOI: 10.1021/acs.jmedchem.5b00951 BindingDB Entry DOI: 10.7270/Q2G73GKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50124578 (CHEMBL3621533) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Savitribai Phule Pune University (formerly University of Pune) Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrate | J Med Chem 58: 7820-32 (2015) Article DOI: 10.1021/acs.jmedchem.5b00951 BindingDB Entry DOI: 10.7270/Q2G73GKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50590565 (CHEMBL5199547) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114621 BindingDB Entry DOI: 10.7270/Q2QN6BSD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50590564 (CHEMBL5179216) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114621 BindingDB Entry DOI: 10.7270/Q2QN6BSD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50579646 (CHEMBL5078012) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Jack bean alpha-mannosidase by Lineweaver-Burk plot | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00036 BindingDB Entry DOI: 10.7270/Q28G8QK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525016 (CHEMBL4457217) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525020 (CHEMBL4518572) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525018 (CHEMBL4465842) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525017 (CHEMBL4462117) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525014 (CHEMBL4475419) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525015 (CHEMBL4435118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50124580 (CHEMBL3621530) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Savitribai Phule Pune University (formerly University of Pune) Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrate | J Med Chem 58: 7820-32 (2015) Article DOI: 10.1021/acs.jmedchem.5b00951 BindingDB Entry DOI: 10.7270/Q2G73GKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525019 (CHEMBL4471561) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50525021 (CHEMBL4483772) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis | J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50236278 (CHEMBL4077472) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | J Med Chem 60: 1829-1842 (2017) Article DOI: 10.1021/acs.jmedchem.6b01550 BindingDB Entry DOI: 10.7270/Q2K939S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50236280 (CHEMBL4100971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sevilla Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometry | J Med Chem 60: 1829-1842 (2017) Article DOI: 10.1021/acs.jmedchem.6b01550 BindingDB Entry DOI: 10.7270/Q2K939S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114621 BindingDB Entry DOI: 10.7270/Q2QN6BSD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using p-nitrophenyl-mannopyranoside as substrate measured every 2 mins | Eur J Med Chem 123: 155-160 (2016) Article DOI: 10.1016/j.ejmech.2016.07.021 BindingDB Entry DOI: 10.7270/Q2C24ZD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50204663 (CHEMBL3894489) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Mixed-type inhibition of jack bean alpha-mannosidase assessed as enzyme-substrate-inhibitor complex using o-orp-nitrophenyl-glycopyranoside as substr... | Eur J Med Chem 123: 155-160 (2016) Article DOI: 10.1016/j.ejmech.2016.07.021 BindingDB Entry DOI: 10.7270/Q2C24ZD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50204663 (CHEMBL3894489) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Mixed-type inhibition of jack bean alpha-mannosidase assessed as enzyme-inhibitor complex using o-orp-nitrophenyl-glycopyranoside as substrate by Lin... | Eur J Med Chem 123: 155-160 (2016) Article DOI: 10.1016/j.ejmech.2016.07.021 BindingDB Entry DOI: 10.7270/Q2C24ZD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase (Canavalia ensiformis) | BDBM50204661 (CHEMBL3892394) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of jack bean alpha-mannosidase using o-orp-nitrophenyl-glycopyranoside as substrate by Lineweaver-Burk plot method | Eur J Med Chem 123: 155-160 (2016) Article DOI: 10.1016/j.ejmech.2016.07.021 BindingDB Entry DOI: 10.7270/Q2C24ZD6 | |||||||||||
More data for this Ligand-Target Pair |