BindingDB PrimarySearch

Found 14 hits of ki data for polymerid = 8398
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50607111 (CHEMBL5218807) Show SMILES Cc1c(Br)cc(NC(=O)NS(O)(=O)=O)cc1Br Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01143 BindingDB Entry DOI: 10.7270/Q2BK1HGF
TBA					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50256796 (6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50256796 (6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM199180 (US9217012, 10) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	>-34.2	n/a	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50558461 (CHEMBL4760367) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4
TBA					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50558482 (CHEMBL4742123) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of LMW-PTP isoform B (unknown origin) using para-nitrophenyl phosphate as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50257418 (7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50257294 (7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50257418 (7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50558482 (CHEMBL4742123) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50250606 (CHEMBL4077342) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...				J Med Chem 60: 9299-9319 (2017) Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50257294 (7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and R.E. Curated by ChEMBL					Assay Description Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assay				Bioorg Med Chem 17: 2658-72 (2009) Article DOI: 10.1016/j.bmc.2009.02.060 BindingDB Entry DOI: 10.7270/Q2K0745F
University of Modena and R.E. Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50118216 ((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...) Show SMILES Cc1ncc(COP(O)(O)=O)c(C=O)c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Saint John's University Curated by ChEMBL					Assay Description Competitive inhibition of LMW-PTP isoform A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127342 BindingDB Entry DOI: 10.7270/Q2FJ2MBV
Saint John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human HCPTPA				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair