Compile Data Set for Download or QSAR

Found 3016 hits Enz. Inhib. hit(s) with Target = 'Fatty acid amide hydrolase (FAAH)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339872 ((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...) Show SMILES FC(F)(F)Cn1c2cccnc2n([C@H]2CCCN(C2)c2nccc(n2)-c2ccc(Cl)s2)c1=O |r| Show InChI InChI=1S/C21H18ClF3N6OS/c22-17-6-5-16(33-17)14-7-9-27-19(28-14)29-10-2-3-13(11-29)31-18-15(4-1-8-26-18)30(20(31)32)12-21(23,24)25/h1,4-9,13H,2-3,10-12H2/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation counting				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339871 ((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...) Show SMILES CCn1c2cccnc2n([C@H]2CCCN(C2)c2nccc(n2)-c2ccc(Cl)s2)c1=O |r| Show InChI InChI=1S/C21H21ClN6OS/c1-2-27-16-6-3-10-23-19(16)28(21(27)29)14-5-4-12-26(13-14)20-24-11-9-15(25-20)17-7-8-18(22)30-17/h3,6-11,14H,2,4-5,12-13H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation counting				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339886 ((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...) Show SMILES CCn1c2cccnc2n([C@H]2CCCN(C2)c2cc(nc(N)n2)-c2ccc(F)cc2)c1=O |r| Show InChI InChI=1S/C23H24FN7O/c1-2-30-19-6-3-11-26-21(19)31(23(30)32)17-5-4-12-29(14-17)20-13-18(27-22(25)28-20)15-7-9-16(24)10-8-15/h3,6-11,13,17H,2,4-5,12,14H2,1H3,(H2,25,27,28)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation counting				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339891 ((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...) Show SMILES CCn1c2cccnc2n([C@H]2CCCN(C2)c2nccc(n2)-c2cccs2)c1=O |r| Show InChI InChI=1S/C21H22N6OS/c1-2-26-17-7-3-10-22-19(17)27(21(26)28)15-6-4-12-25(14-15)20-23-11-9-16(24-20)18-8-5-13-29-18/h3,5,7-11,13,15H,2,4,6,12,14H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation counting				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166868 (CHEMBL3797635) Show SMILES O=C(Oc1cccc(c1)C#N)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:25| Show InChI InChI=1S/C25H21NO7/c27-20(16-7-10-21-22(13-16)32-12-11-31-21)14-33-25(30)15-5-8-17(9-6-15)26-23(28)18-3-1-2-4-19(18)24(26)29/h1-2,5-10,13,28-29H,3-4,11-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166873 (CHEMBL3800456) Show SMILES Cc1ccccc1OC(=O)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:24| Show InChI InChI=1S/C21H19NO5/c1-13-3-4-16(11-14(13)2)18(23)12-27-21(26)15-5-7-17(8-6-15)22-19(24)9-10-20(22)25/h3-11,24-25H,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166871 (CHEMBL3797841) Show SMILES Clc1ccccc1OC(=O)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:24| Show InChI InChI=1S/C26H23NO5/c28-23(19-9-8-16-4-3-5-18(16)14-19)15-32-26(31)17-10-12-20(13-11-17)27-24(29)21-6-1-2-7-22(21)25(27)30/h1-2,8-14,29-30H,3-7,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166866 (CHEMBL3798156) Show SMILES O=C(Oc1ccccc1)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:23| Show InChI InChI=1S/C22H21NO5/c1-14-6-7-17(12-15(14)2)19(24)13-28-22(27)16-8-10-18(11-9-16)23-20(25)4-3-5-21(23)26/h6-12H,3-5,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166869 (CHEMBL3799744) Show SMILES Clc1ccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)cc1 |t:21| Show InChI InChI=1S/C25H23NO7/c1-31-21-12-9-16(13-22(21)32-2)20(27)14-33-25(30)15-7-10-17(11-8-15)26-23(28)18-5-3-4-6-19(18)24(26)29/h3-4,7-13,28-29H,5-6,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166866 (CHEMBL3798156) Show SMILES O=C(Oc1ccccc1)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:23| Show InChI InChI=1S/C22H21NO5/c1-14-6-7-17(12-15(14)2)19(24)13-28-22(27)16-8-10-18(11-9-16)23-20(25)4-3-5-21(23)26/h6-12H,3-5,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166890 (CHEMBL3797809) Show SMILES O=C(Oc1ccc(cc1)C#N)N1CCN(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:25| Show InChI InChI=1S/C24H21N5O3S/c25-15-17-6-8-19(9-7-17)31-24(30)29-12-10-28(11-13-29)23-26-21(16-33-23)20-14-22(32-27-20)18-4-2-1-3-5-18/h1-9,16,22H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.00800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166867 (CHEMBL3798476) Show SMILES O=C(Oc1ccc(cc1)C#N)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:25| Show InChI InChI=1S/C26H25NO5/c1-15-4-11-21-22(12-15)25(30)27(24(21)29)20-9-7-18(8-10-20)26(31)32-14-23(28)19-6-5-16(2)17(3)13-19/h4-10,13,29-30H,11-12,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166867 (CHEMBL3798476) Show SMILES O=C(Oc1ccc(cc1)C#N)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:25| Show InChI InChI=1S/C26H25NO5/c1-15-4-11-21-22(12-15)25(30)27(24(21)29)20-9-7-18(8-10-20)26(31)32-14-23(28)19-6-5-16(2)17(3)13-19/h4-10,13,29-30H,11-12,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166910 (CHEMBL3798355) Show SMILES FC(F)(F)c1ccc(OC(=O)N2CCN(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)cc1 |t:24| Show InChI InChI=1S/C24H21F3N4O3S/c25-24(26,27)17-6-8-18(9-7-17)33-23(32)31-12-10-30(11-13-31)22-28-20(15-35-22)19-14-21(34-29-19)16-4-2-1-3-5-16/h1-9,15,21H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166911 (CHEMBL3799516) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)cc1 |t:23| Show InChI InChI=1S/C23H21N5O5S/c29-23(32-18-8-6-17(7-9-18)28(30)31)27-12-10-26(11-13-27)22-24-20(15-34-22)19-14-21(33-25-19)16-4-2-1-3-5-16/h1-9,15,21H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166891 (CHEMBL3799008) Show SMILES O=C(Oc1cccc(c1)C#N)N1CCN(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:25| Show InChI InChI=1S/C24H21N5O3S/c25-15-17-5-4-8-19(13-17)31-24(30)29-11-9-28(10-12-29)23-26-21(16-33-23)20-14-22(32-27-20)18-6-2-1-3-7-18/h1-8,13,16,22H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166878 (CHEMBL3800599) Show SMILES Cc1ccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)cc1 |t:21| Show InChI InChI=1S/C27H26N2O6/c30-24(18-5-9-20(10-6-18)28-13-15-34-16-14-28)17-35-27(33)19-7-11-21(12-8-19)29-25(31)22-3-1-2-4-23(22)26(29)32/h1-2,5-12,31-32H,3-4,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166870 (CHEMBL3797226) Show SMILES FC(F)(F)c1ccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)cc1 |t:24| Show InChI InChI=1S/C29H29NO5/c31-26(21-12-10-20(11-13-21)19-6-2-1-3-7-19)18-35-29(34)22-14-16-23(17-15-22)30-27(32)24-8-4-5-9-25(24)28(30)33/h4-5,10-17,19,32-33H,1-3,6-9,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166875 (CHEMBL3797377) Show SMILES Clc1cccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)c1 |t:22| Show InChI InChI=1S/C27H21NO5/c29-24(20-10-9-17-5-1-2-6-19(17)15-20)16-33-27(32)18-11-13-21(14-12-18)28-25(30)22-7-3-4-8-23(22)26(28)31/h1-6,9-15,30-31H,7-8,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166877 (CHEMBL3798594) Show SMILES Cc1cccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)c1 |t:22| Show InChI InChI=1S/C23H23NO5/c1-14-10-21(26)24(22(27)11-14)19-8-6-17(7-9-19)23(28)29-13-20(25)18-5-4-15(2)16(3)12-18/h4-9,12,14H,10-11,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166877 (CHEMBL3798594) Show SMILES Cc1cccc(OC(=O)N2CCC(CC2)c2nc(cs2)C2=NOC(C2)c2ccccc2)c1 |t:22| Show InChI InChI=1S/C23H23NO5/c1-14-10-21(26)24(22(27)11-14)19-8-6-17(7-9-19)23(28)29-13-20(25)18-5-4-15(2)16(3)12-18/h4-9,12,14H,10-11,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161518 (1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...) Show SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161518 (1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...) Show SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Catholique de Louvain Curated by ChEMBL					Assay Description Binding affinity for human fatty acid amide hydrolase				J Med Chem 48: 5059-87 (2005) Article DOI: 10.1021/jm058183t BindingDB Entry DOI: 10.7270/Q2J96753
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50166889 (CHEMBL3799633) Show SMILES O=C(Oc1ccccc1)N1CCN(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1 |t:23| Show InChI InChI=1S/C23H22N4O3S/c28-23(29-18-9-5-2-6-10-18)27-13-11-26(12-14-27)22-24-20(16-31-22)19-15-21(30-25-19)17-7-3-1-4-8-17/h1-10,16,21H,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E.I. Du Pont de Nemours and Company Curated by ChEMBL					Assay Description Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...				Bioorg Med Chem Lett 26: 2965-2973 (2016) Article DOI: 10.1016/j.bmcl.2016.02.061 BindingDB Entry DOI: 10.7270/Q2M32XNP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50228837 (2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161518 (1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...) Show SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161518 (1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...) Show SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50228837 (2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH expressed COS7 cells				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50228837 (2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23316 (7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C19H20N2O2/c22-16(19-21-18-17(23-19)13-8-14-20-18)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23316 (7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C19H20N2O2/c22-16(19-21-18-17(23-19)13-8-14-20-18)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161512 (7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...) Show SMILES O=C(CCCCCCc1ccccc1)c1nnc(o1)-c1ccccn1 Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-23-22-19(25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH (unknown origin) at pH 9				Bioorg Med Chem Lett 18: 5847-50 (2008) Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50275119 (1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...) Show SMILES O=C(CCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C17H16N2O2/c20-14(10-5-4-9-13-7-2-1-3-8-13)17-19-16-15(21-17)11-6-12-18-16/h1-3,6-8,11-12H,4-5,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50275119 (1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...) Show SMILES O=C(CCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C17H16N2O2/c20-14(10-5-4-9-13-7-2-1-3-8-13)17-19-16-15(21-17)11-6-12-18-16/h1-3,6-8,11-12H,4-5,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161520 (1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...) Show SMILES O=C(CCCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C20H22N2O2/c23-17(20-22-19-18(24-20)14-9-15-21-19)13-8-3-1-2-5-10-16-11-6-4-7-12-16/h4,6-7,9,11-12,14-15H,1-3,5,8,10,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161520 (1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...) Show SMILES O=C(CCCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C20H22N2O2/c23-17(20-22-19-18(24-20)14-9-15-21-19)13-8-3-1-2-5-10-16-11-6-4-7-12-16/h4,6-7,9,11-12,14-15H,1-3,5,8,10,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204512 (2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-19-17(21-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204512 (2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-19-17(21-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 54: 2529-91 (2011) Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23069 (3-[4-(benzyloxy)phenyl]-1-[5-(pyridin-2-yl)-1,3-ox...) Show SMILES O=C(CCc1ccc(OCc2ccccc2)cc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C24H20N2O3/c27-22(24-26-16-23(29-24)21-8-4-5-15-25-21)14-11-18-9-12-20(13-10-18)28-17-19-6-2-1-3-7-19/h1-10,12-13,15-16H,11,14,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.450	-53.3	n/a	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute					Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342116 ((S)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnco1 |r| Show InChI InChI=1S/C19H16N2O3/c22-18(19-21-20-12-23-19)15-7-6-14-11-17(9-8-13(14)10-15)24-16-4-2-1-3-5-16/h1-5,8-9,11-12,15H,6-7,10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50372374 (CHEMBL258820) Show SMILES O=C(CCc1ccc(COc2ccccc2)cc1)c1ncc(o1)C#N Show InChI InChI=1S/C20H16N2O3/c21-12-18-13-22-20(25-18)19(23)11-10-15-6-8-16(9-7-15)14-24-17-4-2-1-3-5-17/h1-9,13H,10-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH expressed COS7 cells				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161525 (1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...) Show SMILES O=C(CCCCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C21H24N2O2/c24-18(21-23-20-19(25-21)15-10-16-22-20)14-9-4-2-1-3-6-11-17-12-7-5-8-13-17/h5,7-8,10,12-13,15-16H,1-4,6,9,11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50161525 (1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...) Show SMILES O=C(CCCCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C21H24N2O2/c24-18(21-23-20-19(25-21)15-10-16-22-20)14-9-4-2-1-3-6-11-17-12-7-5-8-13-17/h5,7-8,10,12-13,15-16H,1-4,6,9,11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50350547 (CHEMBL257307) Show SMILES CCCCCCCCCCCC(=O)c1nc2ncccc2o1 Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-8-9-10-12-15(21)18-20-17-16(22-18)13-11-14-19-17/h11,13-14H,2-10,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204478 (1-(5-(4-methylpyridin-2-yl)oxazol-2-yl)-7-phenylhe...) Show SMILES Cc1ccnc(c1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H24N2O2/c1-17-13-14-23-19(15-17)21-16-24-22(26-21)20(25)12-8-3-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-11,13-16H,2-3,5,8-9,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23079 (3-[4-(benzyloxy)phenyl]-1-{pyrido[2,3-d][1,3]oxazo...) Show SMILES O=C(CCc1ccc(OCc2ccccc2)cc1)c1nc2ncccc2o1 Show InChI InChI=1S/C22H18N2O3/c25-19(22-24-21-20(27-22)7-4-14-23-21)13-10-16-8-11-18(12-9-16)26-15-17-5-2-1-3-6-17/h1-9,11-12,14H,10,13,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	-52.6	n/a	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute					Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50372399 (CHEMBL405604) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCc1ccc(COc2ccccc2)cc1 Show InChI InChI=1S/C20H16F3NO3/c21-20(22,23)18-12-24-19(27-18)17(25)11-10-14-6-8-15(9-7-14)13-26-16-4-2-1-3-5-16/h1-9,12H,10-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH expressed COS7 cells				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50350545 (CHEMBL257305) Show SMILES CCCCCCCC(=O)c1nc2ncccc2o1 Show InChI InChI=1S/C14H18N2O2/c1-2-3-4-5-6-8-11(17)14-16-13-12(18-14)9-7-10-15-13/h7,9-10H,2-6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23078 (3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C23H18N2O2/c26-21(23-25-16-22(27-23)20-8-4-5-15-24-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-10,12-13,15-16H,11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50350546 (CHEMBL1812708) Show SMILES CCCCCCCCCC(=O)c1nc2ncccc2o1 Show InChI InChI=1S/C16H22N2O2/c1-2-3-4-5-6-7-8-10-13(19)16-18-15-14(20-16)11-9-12-17-15/h9,11-12H,2-8,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair

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