Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'GABA receptor rho-2 subunit'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50087271 ((E)-4-Amino-but-2-enoic acid (TACA) | 4-Amino-but-...) Show SMILES NC\C=C\C(O)=O Show InChI InChI=1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Partial agonist activity against homomeric rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM85712 (1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMB...) Show SMILES OC(=O)Cc1cnc[nH]1 Show InChI InChI=1S/C5H6N2O2/c8-5(9)1-4-2-6-3-7-4/h2-3H,1H2,(H,6,7)(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Partial agonist activity against human rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50087269 ((cis)-2-Aminomethyl-cyclopropanecarboxylic acid | ...) Show SMILES NCC1CC1C(O)=O Show InChI InChI=1S/C5H9NO2/c6-2-3-1-4(3)5(7)8/h3-4H,1-2,6H2,(H,7,8)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Partial agonist activity with low efficacy against rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50087269 ((cis)-2-Aminomethyl-cyclopropanecarboxylic acid | ...) Show SMILES NCC1CC1C(O)=O Show InChI InChI=1S/C5H9NO2/c6-2-3-1-4(3)5(7)8/h3-4H,1-2,6H2,(H,7,8)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Full agonist activity against human rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50087277 ((Z)-4-Amino-but-2-enoic acid | (Z)-4-aminobut-2-en...) Show SMILES NC\C=C/C(O)=O Show InChI InChI=1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Partial agonist activity againast human rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50087274 (4-Amino-2-methyl-but-2-enoic acid (2-MeTACA) | 4-a...) Show SMILES C\C(=C/CN)C(O)=O Show InChI InChI=1S/C5H9NO2/c1-4(2-3-6)5(7)8/h2H,3,6H2,1H3,(H,7,8)/b4-2+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Activation of human rho2 GABA-C receptor at 34% of maximal GABA-induced response				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50336851 (3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...) Show SMILES NCC1CCP(O)(O)=C1 Show InChI InChI=1S/C5H12NO2P/c6-3-5-1-2-9(7,8)4-5/h4-5,7-8H,1-3,6H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...) Show SMILES NCc1cc(=O)[nH]o1 Show InChI InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Partial agonist activity against human rho-2 subunit GABA-C receptor expressed in Xenopus oocytes				J Med Chem 43: 1427-47 (2000) BindingDB Entry DOI: 10.7270/Q2PZ59HT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50336850 (3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-1-[#6]-[#6]P([#8])([#8])=[#6]1 Show InChI InChI=1S/C5H12N3O2P/c6-5(7)8-4-1-2-11(9,10)3-4/h3-4,9-10H,1-2H2,(H4,6,7,8)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2 (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair