Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-10 (Homo sapiens (Human)) | BDBM192713 (HG-9-91-01 derivative, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192714 (US11725011, Compound YKL-05-95 | YKL-05-095 (3)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192715 (US11725011, Compound YKL-05-96 | YKL-05-096 (4)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192712 (HG-9-91-01 (1)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192716 (US11725011, Compound YKL-05-99 | YKL-05-099 (5)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192718 (HG-9-91-01 derivative, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-10 (Homo sapiens (Human)) | BDBM192717 (HG-9-91-01 derivative, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Broad Institute | Assay Description Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al... | ACS Chem Biol 11: 2105-11 (2016) Article DOI: 10.1021/acschembio.6b00217 BindingDB Entry DOI: 10.7270/Q23777H7 | |||||||||||
More data for this Ligand-Target Pair |