Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nucleophosmin (Homo sapiens (Human)) | BDBM50094238 (CHEMBL3589689) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of phosphorylated NPM1 recruitment to chromatic in 6 Gy irradiated human A549 cells assessed as extraction of pT199NPM1 pretreated 30 mins... | Bioorg Med Chem 23: 3681-6 (2015) Article DOI: 10.1016/j.bmc.2015.04.018 BindingDB Entry DOI: 10.7270/Q2H41T56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nucleophosmin (Homo sapiens (Human)) | BDBM50094237 (CHEMBL593574) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of phosphorylated NPM1 recruitment to chromatic in 6 Gy irradiated human A549 cells assessed as increase in protein solubility as extracti... | Bioorg Med Chem 23: 3681-6 (2015) Article DOI: 10.1016/j.bmc.2015.04.018 BindingDB Entry DOI: 10.7270/Q2H41T56 | |||||||||||
More data for this Ligand-Target Pair |