Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Nck adaptor protein 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytoplasmic protein NCK1 (Homo sapiens (Human))	BDBM50154583 (6-Methyl-quinolin-2-ylamine | CHEMBL361660) Show SMILES Cc1ccc2nc(N)ccc2c1 Show InChI InChI=1S/C10H10N2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3,(H2,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Cytoplasmic protein NCK1 (Homo sapiens (Human))	BDBM14322 (2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...) Show SMILES Nc1ccc2ccccc2n1 Show InChI InChI=1S/C9H8N2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H2,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Cytoplasmic protein NCK1 (Homo sapiens (Human))	BDBM50154587 (6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine | CHEMBL36...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCO1 Show InChI InChI=1S/C12H12N2O2/c13-11-4-2-8-7-9(1-3-10(8)14-11)12-15-5-6-16-12/h1-4,7,12H,5-6H2,(H2,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Cytoplasmic protein NCK1 (Homo sapiens (Human))	BDBM50154582 (6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1 Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair