Compile Data Set for Download or QSAR

Found 14995 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578111 (CHEMBL4861425) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3cc(C)cc(C)c3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0130	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578123 (CHEMBL4872591) Show SMILES Cc1ccc2[nH]c(nc2c1)-c1cncc(-c2cc(C)cc(C)c2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0130	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578124 (CHEMBL4866325) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3cc(F)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0130	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578122 (CHEMBL4849848) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3cc(ccc3[nH]2)C(F)(F)F)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0140	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578121 (CHEMBL4860633) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3cc(Cl)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578128 (CHEMBL4873269) Show SMILES COc1cc(F)cc(c1)-c1cncc(-c2nc3cc(C)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578126 (CHEMBL4853282) Show SMILES Cc1cc(F)cc(c1)-c1cncc(-c2nc3cc(F)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0190	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578120 (CHEMBL4858892) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3cc(ccc3[nH]2)C#N)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0270	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50272772 (10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...) Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r| Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578109 (CHEMBL4863880) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(-c3cc(C)cc(C)c3)c2N2CCC(N)CC2)c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578110 (CHEMBL4845867) Show SMILES Cc1cc(C)cc(c1)C(=O)Nc1cncc(-c2cc(C)cc(C)c2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578118 (CHEMBL4870834) Show SMILES Cc1cc(C(=O)Nc2cncc(-c3cc(Cl)cc(Cl)c3)c2N2CCC(N)CC2)n(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0410	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592204 (CHEMBL5208674) Show SMILES C[C@]1(N)CCN(C1)c1c(cncc1-c1cccc(c1)C#N)-c1nc2c(F)cccc2[nH]1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0470	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578129 (CHEMBL4862195) Show SMILES COc1cc(OC)cc(c1)-c1cncc(-c2nc3cc(C)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0480	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592204 (CHEMBL5208674) Show SMILES C[C@]1(N)CCN(C1)c1c(cncc1-c1cccc(c1)C#N)-c1nc2c(F)cccc2[nH]1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0501	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM81767 (15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.0650	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Effective concentration on human somatostatin receptor 5				Bioorg Med Chem Lett 11: 741-5 (2001) BindingDB Entry DOI: 10.7270/Q2Z3205B
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592201 (CHEMBL5179782) Show SMILES CC1(N)CCN(C1)c1c(cncc1-c1cccc(c1)C#N)-c1nc2c(F)cccc2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0710	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592201 (CHEMBL5179782) Show SMILES CC1(N)CCN(C1)c1c(cncc1-c1cccc(c1)C#N)-c1nc2c(F)cccc2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0710	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592181 (CHEMBL5178891) Show SMILES CC(N)C1CN(C1)c1c(cncc1-c1cc(C)cc(F)c1)-c1nc2c(F)cc(F)cc2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0770	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578127 (CHEMBL4876263) Show SMILES COc1cc(F)cc(c1)-c1cncc(-c2nc3cc(F)ccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0780	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592181 (CHEMBL5178891) Show SMILES CC(N)C1CN(C1)c1c(cncc1-c1cc(C)cc(F)c1)-c1nc2c(F)cc(F)cc2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0794	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578119 (CHEMBL4851978) Show SMILES Cc1cc(C)cc(c1)-c1cncc(-c2nc3ccccc3[nH]2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578125 (CHEMBL4878917) Show SMILES NC1CCN(CC1)c1c(cncc1-c1cc(F)cc(Cl)c1)-c1nc2cc(F)ccc2[nH]1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0810	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592185 (CHEMBL5169724) Show SMILES CC(N)C1CN(C1)c1c(cncc1-c1cc(F)cc(c1)C(F)(F)F)-c1nc2c(F)ccc(F)c2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0880	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50592185 (CHEMBL5169724) Show SMILES CC(N)C1CN(C1)c1c(cncc1-c1cc(F)cc(c1)C(F)(F)F)-c1nc2c(F)ccc(F)c2[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0880	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128807 BindingDB Entry DOI: 10.7270/Q2Q52TK5
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM81767 (15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst2 receptor				Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527731 (US11186590, Compound 1-1) Show SMILES COc1cc(cc2nc([nH]c12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CCC(N)CC1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449006 (US10696689, Compound 3-1) Show SMILES Cc1cc(F)cc(c1)-c1cnc(N)c(-c2nc3c(F)cc(F)cc3[nH]2)c1N1CCC2NCCOC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449010 (US10696689, Compound 3-7) Show SMILES Nc1ncc(-c2cc(F)cc(Cl)c2)c(N2CCC3NCCOC3C2)c1-c1nc2c(F)cc(F)cc2[nH]1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449011 (US10696689, Compound 3-8) Show SMILES COc1cc(F)cc(c1)-c1cnc(N)c(-c2nc3c(F)cc(F)cc3[nH]2)c1N1CCC2NCCOC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449017 (US10696689, Compound 3-14) Show SMILES COc1cc(F)cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CCC2NCCOC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449018 (US10696689, Compound 3-15) Show SMILES CNc1ncc(-c2cc(C)cc(F)c2)c(N2CCC3NCCOC3C2)c1-c1nc2c(OC)cc(F)cc2[nH]1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449019 (2-{4-[(4αS,8αS)-octahydro-1H-pyrido[3,4-...) Show SMILES COc1cc(cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CC[C@@H]2NCCO[C@H]2C1)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449020 (US10696689, Compound 3-17) Show SMILES COc1cc(F)cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(F)cc(Cl)c2)c1N1CCC2NCCOC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311957 (US10166214, Example 93 | US10675268, Example 93 | ...) Show SMILES Cc1cccc2c(n[nH]c12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311970 (US10166214, Example 106 | US10675268, Example 106) Show SMILES Cn1nc(c2cccc(Cl)c12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H21ClN4O/c1-17(2,20-16(23)13-10-7-19-8-11(10)13)15-9-5-4-6-12(18)14(9)22(3)21-15/h4-6,10-11,13,19H,7-8H2,1-3H3,(H,20,23)/t10-,11+,13+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527737 (US11186590, Compound 3-1) Show SMILES Cc1cc(F)cc(c1)-c1cnc(N)c(-c2nc3cc(F)cc(F)c3[nH]2)c1N1CC[C@@H]2NCCO[C@H]2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527741 (US11186590, Compound 3-7) Show SMILES Nc1ncc(-c2cc(F)cc(Cl)c2)c(N2CC[C@@H]3NCCO[C@H]3C2)c1-c1nc2cc(F)cc(F)c2[nH]1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527742 (US11186590, Compound 3-8) Show SMILES COc1cc(F)cc(c1)-c1cnc(N)c(-c2nc3cc(F)cc(F)c3[nH]2)c1N1CC[C@@H]2NCCO[C@H]2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527748 (US11186590, Compound 3-14) Show SMILES COc1cc(F)cc2nc([nH]c12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CC[C@@H]2NCCO[C@H]2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527749 (US11186590, Compound 3-15) Show SMILES CNc1ncc(-c2cc(C)cc(F)c2)c(N2CC[C@@H]3NCCO[C@H]3C2)c1-c1nc2cc(F)cc(OC)c2[nH]1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM449019 (2-{4-[(4αS,8αS)-octahydro-1H-pyrido[3,4-...) Show SMILES COc1cc(cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CC[C@@H]2NCCO[C@H]2C1)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM527751 (US11186590, Compound 3-17) Show SMILES COc1cc(F)cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(F)cc(Cl)c2)c1N1CC[C@@H]2NCCO[C@H]2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KHT
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578117 (CHEMBL4854548) Show SMILES Cn1ncc(C(=O)Nc2cncc(-c3cc(Cl)cc(Cl)c3)c2N2CCC(N)CC2)c1C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311957 (US10166214, Example 93 | US10675268, Example 93 | ...) Show SMILES Cc1cccc2c(n[nH]c12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311970 (US10166214, Example 106 | US10675268, Example 106) Show SMILES Cn1nc(c2cccc(Cl)c12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H21ClN4O/c1-17(2,20-16(23)13-10-7-19-8-11(10)13)15-9-5-4-6-12(18)14(9)22(3)21-15/h4-6,10-11,13,19H,7-8H2,1-3H3,(H,20,23)/t10-,11+,13+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50597579 (CHEMBL5197201) Show SMILES Clc1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00044f BindingDB Entry DOI: 10.7270/Q21C21X0
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM448916 (US10696689, Compound 1-1) Show SMILES COc1cc(cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CCC(N)CC1)C#N Show InChI InChI=1S/C26H26FN7O/c1-14-7-16(11-17(27)8-14)19-13-31-25(30)22(24(19)34-5-3-18(29)4-6-34)26-32-20-9-15(12-28)10-21(35-2)23(20)33-26/h7-11,13,18H,3-6,29H2,1-2H3,(H2,30,31)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<0.100	n/a	n/a	n/a	n/a
CRINETICS PHARMACEUTICALS, INC. US Patent					Assay Description On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...				US Patent US10696689 (2020) BindingDB Entry DOI: 10.7270/Q2FN197F
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50578116 (CHEMBL4862497) Show SMILES Cc1nn(C)cc1C(=O)Nc1cncc(-c2cc(Cl)cc(Cl)c2)c1N1CCC(N)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116424 BindingDB Entry DOI: 10.7270/Q2CF9TXZ
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM506557 (US11045457, Example 157) Show SMILES Cc1ccccc1[C@@H]1CNCC[C@H]1NC(=O)C(C)(C)COc1ncccc1C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.126	n/a	n/a	n/a	n/a
TBA					Assay Description This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN7721
					More data for this Ligand-Target Pair

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