Compile Data Set for Download or QSAR

Found 2458 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50293593 (4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...) Show SMILES Nc1nc(cs1)-c1ccc(O)cc1O Show InChI InChI=1S/C9H8N2O2S/c10-9-11-7(4-14-9)6-2-1-5(12)3-8(6)13/h1-4,12-13H,(H2,10,11)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534050 (CHEMBL4475422) Show SMILES Fc1ccc(cc1F)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H17F2NO3/c26-22-12-9-19(14-23(22)27)24-15-21(31-28-24)16-30-20-10-7-18(8-11-20)25(29)13-6-17-4-2-1-3-5-17/h1-15H,16H2/b13-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534037 (CHEMBL4440265) Show SMILES Clc1ccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)cc1Cl Show InChI InChI=1S/C26H21Cl2N3O/c27-24-14-9-21(16-25(24)28)17-31-18-23(29-30-31)13-8-20-6-11-22(12-7-20)26(32)15-10-19-4-2-1-3-5-19/h1-7,9-12,14-16,18H,8,13,17H2/b15-10+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534060 (CHEMBL4465047) Show SMILES Clc1ccc(cc1Cl)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H17Cl2NO3/c26-22-12-9-19(14-23(22)27)24-15-21(31-28-24)16-30-20-10-7-18(8-11-20)25(29)13-6-17-4-2-1-3-5-17/h1-15H,16H2/b13-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534034 (CHEMBL4464052) Show SMILES Fc1cc(ccc1Cl)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H17ClFNO3/c26-22-12-9-19(14-23(22)27)24-15-21(31-28-24)16-30-20-10-7-18(8-11-20)25(29)13-6-17-4-2-1-3-5-17/h1-15H,16H2/b13-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534035 (CHEMBL4470012) Show SMILES Fc1cccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)c1 Show InChI InChI=1S/C26H22FN3O/c27-24-8-4-7-22(17-24)18-30-19-25(28-29-30)15-11-21-9-13-23(14-10-21)26(31)16-12-20-5-2-1-3-6-20/h1-10,12-14,16-17,19H,11,15,18H2/b16-12+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534051 (CHEMBL4522700) Show SMILES Fc1ccc(cc1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H18FNO3/c26-21-11-7-19(8-12-21)24-16-23(30-27-24)17-29-22-13-9-20(10-14-22)25(28)15-6-18-4-2-1-3-5-18/h1-16H,17H2/b15-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534048 (CHEMBL4545495) Show SMILES Clc1ccc(cc1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H18ClNO3/c26-21-11-7-19(8-12-21)24-16-23(30-27-24)17-29-22-13-9-20(10-14-22)25(28)15-6-18-4-2-1-3-5-18/h1-16H,17H2/b15-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534052 (CHEMBL4469401) Show SMILES Clc1ccc(\C=C\C(=O)c2ccc3nc(NC(=O)c4ccccc4)sc3c2)cc1 Show InChI InChI=1S/C23H15ClN2O2S/c24-18-10-6-15(7-11-18)8-13-20(27)17-9-12-19-21(14-17)29-23(25-19)26-22(28)16-4-2-1-3-5-16/h1-14H,(H,25,26,28)/b13-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534054 (CHEMBL4463325) Show SMILES Ic1ccc(o1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C23H16INO4/c24-23-13-12-22(28-23)20-14-19(29-25-20)15-27-18-9-7-17(8-10-18)21(26)11-6-16-4-2-1-3-5-16/h1-14H,15H2/b11-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534061 (CHEMBL4460236) Show SMILES Clc1cccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)c1 Show InChI InChI=1S/C26H22ClN3O/c27-24-8-4-7-22(17-24)18-30-19-25(28-29-30)15-11-21-9-13-23(14-10-21)26(31)16-12-20-5-2-1-3-6-20/h1-10,12-14,16-17,19H,11,15,18H2/b16-12+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534047 (CHEMBL4581303) Show SMILES Clc1cc(Cl)cc(c1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H17Cl2NO3/c26-20-12-19(13-21(27)14-20)24-15-23(31-28-24)16-30-22-9-7-18(8-10-22)25(29)11-6-17-4-2-1-3-5-17/h1-15H,16H2/b11-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534036 (CHEMBL4462337) Show SMILES Fc1ccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)cc1 Show InChI InChI=1S/C26H22FN3O/c27-24-14-8-22(9-15-24)18-30-19-25(28-29-30)16-10-21-6-12-23(13-7-21)26(31)17-11-20-4-2-1-3-5-20/h1-9,11-15,17,19H,10,16,18H2/b17-11+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50041234 (6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta...) Show SMILES COc1c2occc2cc2ccc(=O)oc12 Show InChI InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534039 (CHEMBL4473442) Show SMILES Cc1ccc(\C=C\C(=O)c2ccc3nc(NC(=O)c4ccccc4)sc3c2)cc1 Show InChI InChI=1S/C24H18N2O2S/c1-16-7-9-17(10-8-16)11-14-21(27)19-12-13-20-22(15-19)29-24(25-20)26-23(28)18-5-3-2-4-6-18/h2-15H,1H3,(H,25,26,28)/b14-11+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534041 (CHEMBL4559940) Show SMILES Clc1ccc(\C=C\C(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H16ClNO2/c23-19-11-6-16(7-12-19)8-15-21(25)17-9-13-20(14-10-17)24-22(26)18-4-2-1-3-5-18/h1-15H,(H,24,26)/b15-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534056 (CHEMBL4466784) Show SMILES Fc1cccc(c1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H18FNO3/c26-21-8-4-7-20(15-21)24-16-23(30-27-24)17-29-22-12-10-19(11-13-22)25(28)14-9-18-5-2-1-3-6-18/h1-16H,17H2/b14-9+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534049 (CHEMBL4453720) Show SMILES Clc1cccc(c1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H18ClNO3/c26-21-8-4-7-20(15-21)24-16-23(30-27-24)17-29-22-12-10-19(11-13-22)25(28)14-9-18-5-2-1-3-6-18/h1-16H,17H2/b14-9+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534058 (CHEMBL4462990) Show SMILES Clc1ccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)cc1 Show InChI InChI=1S/C26H22ClN3O/c27-24-14-8-22(9-15-24)18-30-19-25(28-29-30)16-10-21-6-12-23(13-7-21)26(31)17-11-20-4-2-1-3-5-20/h1-9,11-15,17,19H,10,16,18H2/b17-11+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.39E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534045 (CHEMBL4567344) Show SMILES FC(F)(F)Oc1cccc(c1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C26H18F3NO4/c27-26(28,29)33-22-8-4-7-20(15-22)24-16-23(34-30-24)17-32-21-12-10-19(11-13-21)25(31)14-9-18-5-2-1-3-6-18/h1-16H,17H2/b14-9+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534053 (CHEMBL3409828) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18ClNO3S/c1-16-2-13-21(14-3-16)28(26,27)24-20-11-7-18(8-12-20)22(25)15-6-17-4-9-19(23)10-5-17/h2-15,24H,1H3/b15-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534044 (CHEMBL4548215) Show SMILES CN(C)c1ccc(cc1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C27H24N2O3/c1-29(2)23-13-9-21(10-14-23)26-18-25(32-28-26)19-31-24-15-11-22(12-16-24)27(30)17-8-20-6-4-3-5-7-20/h3-18H,19H2,1-2H3/b17-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.89E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534040 (CHEMBL4468479) Show SMILES Nc1nc2ccc(cc2s1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11ClN2OS/c17-12-5-1-10(2-6-12)3-8-14(20)11-4-7-13-15(9-11)21-16(18)19-13/h1-9H,(H2,18,19)/b8-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534043 (CHEMBL4446279) Show SMILES Cc1ccc(o1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C24H19NO4/c1-17-7-14-24(28-17)22-15-21(29-25-22)16-27-20-11-9-19(10-12-20)23(26)13-8-18-5-3-2-4-6-18/h2-15H,16H2,1H3/b13-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534038 (CHEMBL4592732) Show SMILES COc1cccc(Cn2cc(CCc3ccc(cc3)C(=O)\C=C\c3ccccc3)nn2)c1 Show InChI InChI=1S/C27H25N3O2/c1-32-26-9-5-8-23(18-26)19-30-20-25(28-29-30)16-12-22-10-14-24(15-11-22)27(31)17-13-21-6-3-2-4-7-21/h2-11,13-15,17-18,20H,12,16,19H2,1H3/b17-13+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.74E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534046 (CHEMBL4594133) Show SMILES COc1ccc(cc1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C26H21NO4/c1-29-22-12-8-20(9-13-22)25-17-24(31-27-25)18-30-23-14-10-21(11-15-23)26(28)16-7-19-5-3-2-4-6-19/h2-17H,18H2,1H3/b16-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.72E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534042 (CHEMBL4469461) Show SMILES O=C(\C=C\c1ccccc1)c1ccc(OCc2cc(no2)-c2cccs2)cc1 Show InChI InChI=1S/C23H17NO3S/c25-22(13-8-17-5-2-1-3-6-17)18-9-11-19(12-10-18)26-16-20-15-21(24-27-20)23-7-4-14-28-23/h1-15H,16H2/b13-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534055 (CHEMBL4522932) Show SMILES COc1ccccc1-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C26H21NO4/c1-29-26-10-6-5-9-23(26)24-17-22(31-27-24)18-30-21-14-12-20(13-15-21)25(28)16-11-19-7-3-2-4-8-19/h2-17H,18H2,1H3/b16-11+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.53E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534059 (CHEMBL4471626) Show SMILES O=C(\C=C\c1ccccc1)c1ccc(OCc2cc(no2)-c2ccccc2)cc1 Show InChI InChI=1S/C25H19NO3/c27-25(16-11-19-7-3-1-4-8-19)21-12-14-22(15-13-21)28-18-23-17-24(26-29-23)20-9-5-2-6-10-20/h1-17H,18H2/b16-11+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.81E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50322068 ((-)-N-Formylanonaine | CHEMBL1170090) Show SMILES O=CN1CCc2cc3OCOc3c3-c4ccccc4C[C@@H]1c23 |r| Show InChI InChI=1S/C18H15NO3/c20-9-19-6-5-12-8-15-18(22-10-21-15)17-13-4-2-1-3-11(13)7-14(19)16(12)17/h1-4,8-9,14H,5-7,10H2/t14-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of tyrosinase in human HEMn-MP assessed as reduction of melanin level after 2 days by spectrophotometric analysis				Bioorg Med Chem 18: 5241-7 (2010) Article DOI: 10.1016/j.bmc.2010.05.045 BindingDB Entry DOI: 10.7270/Q2JS9RFV
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534033 (CHEMBL4473153) Show SMILES O=C(\C=C\c1ccccc1)c1ccc(OCc2cc(no2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C27H21NO5/c29-25(12-6-19-4-2-1-3-5-19)20-7-10-22(11-8-20)32-18-23-17-24(28-33-23)21-9-13-26-27(16-21)31-15-14-30-26/h1-13,16-17H,14-15,18H2/b12-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50534057 (CHEMBL4542422) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(COc2ccc(cc2)C(=O)\C=C\c2ccccc2)on1 Show InChI InChI=1S/C25H18N2O5/c28-25(15-6-18-4-2-1-3-5-18)20-9-13-22(14-10-20)31-17-23-16-24(26-32-23)19-7-11-21(12-8-19)27(29)30/h1-16H,17H2/b15-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELIS...				Bioorg Med Chem 24: 5440-5448 (2016) Article DOI: 10.1016/j.bmc.2016.08.066 BindingDB Entry DOI: 10.7270/Q2X351ZW
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50269559 (2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1ccc(c(O)c1)-c1cc(=O)c2c(O)cc(O)cc2o1 Show InChI InChI=1S/C15H10O6/c16-7-1-2-9(10(18)3-7)13-6-12(20)15-11(19)4-8(17)5-14(15)21-13/h1-6,16-19H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.610	-53.5	n/a	n/a	n/a	n/a	n/a	n/a	30
Gyeongsang National University					Assay Description Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...				J Enzyme Inhib Med Chem 23: 922-30 (2008) Article DOI: 10.1080/14756360701810207 BindingDB Entry DOI: 10.7270/Q2P849G3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50134709 (CHEMBL3747057) Show SMILES COc1c2C[C@@H](COc2cc2OC(C)(C)C=Cc12)c1ccc(O)cc1O |r,c:16| Show InChI InChI=1S/C21H22O5/c1-21(2)7-6-15-19(26-21)10-18-16(20(15)24-3)8-12(11-25-18)14-5-4-13(22)9-17(14)23/h4-7,9-10,12,22-23H,8,11H2,1-3H3/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...				Bioorg Med Chem 24: 153-9 (2016) Article DOI: 10.1016/j.bmc.2015.11.040 BindingDB Entry DOI: 10.7270/Q2RN39PT
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50502237 (CHEMBL4470451) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CSc3nc4ccccc4[nH]3)ccc12 Show InChI InChI=1S/C23H20N4OS/c1-2-27-20-10-6-3-7-16(20)17-13-15(11-12-21(17)27)24-22(28)14-29-23-25-18-8-4-5-9-19(18)26-23/h3-13H,2,14H2,1H3,(H,24,28)(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	CHEMBL5274383 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50568146 (CHEMBL1481541) Show SMILES COc1ccccc1-c1nnc(SCC(=O)Nc2ccccc2)o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Noncompetitive inhibition of mushroom tyrosinase assessed as dissociation constant using L-DOPA as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.bmc.2021.116222 BindingDB Entry DOI: 10.7270/Q24171T1
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	CHEMBL5277261 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars		4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50134709 (CHEMBL3747057) Show SMILES COc1c2C[C@@H](COc2cc2OC(C)(C)C=Cc12)c1ccc(O)cc1O |r,c:16| Show InChI InChI=1S/C21H22O5/c1-21(2)7-6-15-19(26-21)10-18-16(20(15)24-3)8-12(11-25-18)14-5-4-13(22)9-17(14)23/h4-7,9-10,12,22-23H,8,11H2,1-3H3/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...				Bioorg Med Chem 24: 153-9 (2016) Article DOI: 10.1016/j.bmc.2015.11.040 BindingDB Entry DOI: 10.7270/Q2RN39PT
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330795 (2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...) Show SMILES CC(C)c1ccc(O)c(=O)cc1 Show InChI InChI=1S/C10H12O2/c1-7(2)8-3-5-9(11)10(12)6-4-8/h3-7H,1-2H3,(H,11,12)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysis				Bioorg Med Chem 18: 8112-8 (2010) Article DOI: 10.1016/j.bmc.2010.08.056 BindingDB Entry DOI: 10.7270/Q2JH3MF5
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50569812 (CHEMBL4869068) Show SMILES Oc1coc(Cn2cc(COc3cc(=O)oc4ccccc34)nn2)cc1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112480 BindingDB Entry DOI: 10.7270/Q2WW7NGF
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50343137 (CHEMBL1770313 | Cyclomorusin | Cycolmorusin, 2) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-1-[#8]-c2cc(-[#8])ccc2-c2oc3c4-[#6]=[#6]C([#6])([#6])[#8]-c4cc(-[#8])c3c(=O)c12 |c:18| Show InChI InChI=1S/C25H22O6/c1-12(2)9-19-21-22(28)20-16(27)11-18-15(7-8-25(3,4)31-18)23(20)30-24(21)14-6-5-13(26)10-17(14)29-19/h5-11,19,26-27H,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	46.4	-42.6	n/a	n/a	n/a	n/a	n/a	n/a	30
Gyeongsang National University					Assay Description Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...				J Enzyme Inhib Med Chem 23: 922-30 (2008) Article DOI: 10.1080/14756360701810207 BindingDB Entry DOI: 10.7270/Q2P849G3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50254430 (CHEMBL468906 | broussonin C) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])ccc1-[#8] Show InChI InChI=1S/C20H24O3/c1-14(2)6-8-17-12-15(7-11-19(17)22)4-3-5-16-9-10-18(21)13-20(16)23/h6-7,9-13,21-23H,3-5,8H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem	Article PubMed	48.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase by kinetic based assay				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM91591 (Mormin, 1) Show SMILES C\C(CO)=C/Cc1c(oc2c3C=CC(C)(CO)Oc3cc(O)c2c1=O)-c1ccc(O)cc1O |c:11| Show InChI InChI=1S/C25H24O8/c1-13(11-26)3-5-17-22(31)21-19(30)10-20-16(7-8-25(2,12-27)33-20)24(21)32-23(17)15-6-4-14(28)9-18(15)29/h3-4,6-10,26-30H,5,11-12H2,1-2H3/b13-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	49.2	-42.4	n/a	n/a	n/a	n/a	n/a	n/a	30
Gyeongsang National University					Assay Description Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...				J Enzyme Inhib Med Chem 23: 922-30 (2008) Article DOI: 10.1080/14756360701810207 BindingDB Entry DOI: 10.7270/Q2P849G3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI InChI=1S/C10H12O2/c1-7(2)8-4-3-5-9(11)10(12)6-8/h3-7H,1-2H3,(H,11,12)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysis				Bioorg Med Chem 18: 8112-8 (2010) Article DOI: 10.1016/j.bmc.2010.08.056 BindingDB Entry DOI: 10.7270/Q2JH3MF5
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50569806 (CHEMBL4865646) Show SMILES COc1cc(ccc1OCc1cn(Cc2cc(=O)c(O)co2)nn1)C(C)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112480 BindingDB Entry DOI: 10.7270/Q2WW7NGF
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	CHEMBL5287587 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50242015 (CHEMBL518543 | Kuwanon C, 4 | kuwanon C) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2c1oc(-c1ccc(-[#8])cc1-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2=O Show InChI InChI=1S/C25H26O6/c1-13(2)5-8-17-20(28)12-21(29)22-23(30)18(9-6-14(3)4)24(31-25(17)22)16-10-7-15(26)11-19(16)27/h5-7,10-12,26-29H,8-9H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	80.5	-41.2	n/a	n/a	n/a	n/a	n/a	n/a	30
Gyeongsang National University					Assay Description Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...				J Enzyme Inhib Med Chem 23: 922-30 (2008) Article DOI: 10.1080/14756360701810207 BindingDB Entry DOI: 10.7270/Q2P849G3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50569801 (CHEMBL4867662) Show SMILES CC(C)c1ccc(C)c(OCc2cn(Cc3cc(=O)c(O)co3)nn2)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112480 BindingDB Entry DOI: 10.7270/Q2WW7NGF
					More data for this Ligand-Target Pair

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