Found 10 hits Enz. Inhib. hit(s) with Target = 'Beta-ketoacyl-ACP-synthase III' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245829
(2-(methylsulfonyl)naphthalene-1,4-diol | CHEMBL491...)Show InChI InChI=1S/C11H10O4S/c1-16(14,15)10-6-9(12)7-4-2-3-5-8(7)11(10)13/h2-6,12-13H,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245878
(CHEMBL512926 | N-(4-(1,4-dihydroxynaphthalen-2-yls...)Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)c1cc(O)c2ccccc2c1O Show InChI InChI=1S/C18H15NO5S/c1-11(20)19-12-6-8-13(9-7-12)25(23,24)17-10-16(21)14-4-2-3-5-15(14)18(17)22/h2-10,21-22H,1H3,(H,19,20) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245830
(3-(1,4-dihydroxynaphthalen-2-ylsulfonyl)propanoic ...)Show InChI InChI=1S/C13H12O6S/c14-10-7-11(20(18,19)6-5-12(15)16)13(17)9-4-2-1-3-8(9)10/h1-4,7,14,17H,5-6H2,(H,15,16) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 46.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245880
(2-(4-propylphenylsulfonyl)naphthalene-1,4-diol | C...)Show InChI InChI=1S/C19H18O4S/c1-2-5-13-8-10-14(11-9-13)24(22,23)18-12-17(20)15-6-3-4-7-16(15)19(18)21/h3-4,6-12,20-21H,2,5H2,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 72.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245828
(2-Tosylnaphthalene-1,4-diol | CHEMBL509952)Show InChI InChI=1S/C17H14O4S/c1-11-6-8-12(9-7-11)22(20,21)16-10-15(18)13-4-2-3-5-14(13)17(16)19/h2-10,18-19H,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 73.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245879
(2-(4-chlorophenylsulfonyl)naphthalene-1,4-diol | C...)Show InChI InChI=1S/C16H11ClO4S/c17-10-5-7-11(8-6-10)22(20,21)15-9-14(18)12-3-1-2-4-13(12)16(15)19/h1-9,18-19H | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245877
(2-(phenylsulfonyl)naphthalene-1,4-diol | CHEMBL462...)Show InChI InChI=1S/C16H12O4S/c17-14-10-15(16(18)13-9-5-4-8-12(13)14)21(19,20)11-6-2-1-3-7-11/h1-10,17-18H | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 279 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245924
(2-tosylanthracene-1,4-diol | CHEMBL451059)Show SMILES Cc1ccc(cc1)S(=O)(=O)c1cc(O)c2cc3ccccc3cc2c1O Show InChI InChI=1S/C21H16O4S/c1-13-6-8-16(9-7-13)26(24,25)20-12-19(22)17-10-14-4-2-3-5-15(14)11-18(17)21(20)23/h2-12,22-23H,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 341 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245923
(2-(naphthalen-2-ylsulfonyl)naphthalene-1,4-diol | ...)Show SMILES Oc1cc(c(O)c2ccccc12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C20H14O4S/c21-18-12-19(20(22)17-8-4-3-7-16(17)18)25(23,24)15-10-9-13-5-1-2-6-14(13)11-15/h1-12,21-22H | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 393 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
Beta-ketoacyl-[acyl-carrier-protein] synthase III
(Plasmodium falciparum) | BDBM50245928
(2-tosylnaphthalene-1,4-dione | CHEMBL454282)Show SMILES Cc1ccc(cc1)S(=O)(=O)C1=CC(=O)c2ccccc2C1=O |t:11| Show InChI InChI=1S/C17H12O4S/c1-11-6-8-12(9-7-11)22(20,21)16-10-15(18)13-4-2-3-5-14(13)17(16)19/h2-10H,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum FabH |
Bioorg Med Chem Lett 18: 6402-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.097
BindingDB Entry DOI: 10.7270/Q2542PGV |
More data for this
Ligand-Target Pair | |
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