Found 126 hits Enz. Inhib. hit(s) with Target = 'CD209 antigen' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509061
(CHEMBL4554703)Show SMILES CC(C)(C)c1cc2Cc3cc(cc(Cc4cc(cc(Cc5cc(cc(Cc(c1)c2OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)nn2)nn1)c5OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)nn2)nn1)C(C)(C)C)c4OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)nn2)nn1)C(C)(C)C)c3OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)nn2)nn1)C(C)(C)C |r| Show InChI InChI=1S/C128H188N28O36/c1-125(2,3)85-49-77-45-79-51-86(126(4,5)6)53-81(118(79)182-42-26-38-150-58-90(130-138-150)66-154(178)102(162)30-18-14-22-34-146-62-94(134-142-146)74-186-122-114(174)110(170)106(166)98(70-158)190-122)47-83-55-88(128(10,11)12)56-84(120(83)184-44-28-40-152-60-92(132-140-152)68-156(180)104(164)32-20-16-24-36-148-64-96(136-144-148)76-188-124-116(176)112(172)108(168)100(72-160)192-124)48-82-54-87(127(7,8)9)52-80(119(82)183-43-27-39-151-59-91(131-139-151)67-155(179)103(163)31-19-15-23-35-147-63-95(135-143-147)75-187-123-115(175)111(171)107(167)99(71-159)191-123)46-78(50-85)117(77)181-41-25-37-149-57-89(129-137-149)65-153(177)101(161)29-17-13-21-33-145-61-93(133-141-145)73-185-121-113(173)109(169)105(165)97(69-157)189-121/h49-64,97-100,105-116,121-124,157-160,165-180H,13-48,65-76H2,1-12H3/t97-,98-,99-,100-,105-,106-,107-,108-,109+,110+,111+,112+,113+,114+,115+,116+,121+,122+,123+,124+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 156 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombina... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509063
(CHEMBL4515649)Show SMILES C[C@@H]1O[C@@H](OCc2cn(CCCCCC(=O)N(O)Cc3cn(CCCOc4c5Cc6cc(cc(Cc7cc(cc(Cc8cc(cc(Cc4cc(c5)C(C)(C)C)c8OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]8O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]8O)nn5)nn4)C(C)(C)C)c7OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]7O)nn5)nn4)C(C)(C)C)c6OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn4)C(C)(C)C)nn3)nn2)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C128H188N28O32/c1-77-105(161)109(165)113(169)121(185-77)181-73-97-65-145(141-133-97)37-25-17-21-33-101(157)153(173)69-93-61-149(137-129-93)41-29-45-177-117-81-49-83-55-90(126(8,9)10)57-85(118(83)178-46-30-42-150-62-94(130-138-150)70-154(174)102(158)34-22-18-26-38-146-66-98(134-142-146)74-182-122-114(170)110(166)106(162)78(2)186-122)51-87-59-92(128(14,15)16)60-88(120(87)180-48-32-44-152-64-96(132-140-152)72-156(176)104(160)36-24-20-28-40-148-68-100(136-144-148)76-184-124-116(172)112(168)108(164)80(4)188-124)52-86-58-91(127(11,12)13)56-84(50-82(117)54-89(53-81)125(5,6)7)119(86)179-47-31-43-151-63-95(131-139-151)71-155(175)103(159)35-23-19-27-39-147-67-99(135-143-147)75-183-123-115(171)111(167)107(163)79(3)187-123/h53-68,77-80,105-116,121-124,161-176H,17-52,69-76H2,1-16H3/t77-,78-,79-,80-,105+,106+,107+,108+,109+,110+,111+,112+,113-,114-,115-,116-,121+,122+,123+,124+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombina... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580861
(CHEMBL5079779)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3Cc4cc(cc(Cc5cc(cc(Cc6cc(cc(Cc2cc(c3)C(C)(C)C)c6OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn3)nn2)C(C)(C)C)c5OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn3)nn2)C(C)(C)C)c4OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509063
(CHEMBL4515649)Show SMILES C[C@@H]1O[C@@H](OCc2cn(CCCCCC(=O)N(O)Cc3cn(CCCOc4c5Cc6cc(cc(Cc7cc(cc(Cc8cc(cc(Cc4cc(c5)C(C)(C)C)c8OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]8O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]8O)nn5)nn4)C(C)(C)C)c7OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]7O)nn5)nn4)C(C)(C)C)c6OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn4)C(C)(C)C)nn3)nn2)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C128H188N28O32/c1-77-105(161)109(165)113(169)121(185-77)181-73-97-65-145(141-133-97)37-25-17-21-33-101(157)153(173)69-93-61-149(137-129-93)41-29-45-177-117-81-49-83-55-90(126(8,9)10)57-85(118(83)178-46-30-42-150-62-94(130-138-150)70-154(174)102(158)34-22-18-26-38-146-66-98(134-142-146)74-182-122-114(170)110(166)106(162)78(2)186-122)51-87-59-92(128(14,15)16)60-88(120(87)180-48-32-44-152-64-96(132-140-152)72-156(176)104(160)36-24-20-28-40-148-68-100(136-144-148)76-184-124-116(172)112(168)108(164)80(4)188-124)52-86-58-91(127(11,12)13)56-84(50-82(117)54-89(53-81)125(5,6)7)119(86)179-47-31-43-151-63-95(131-139-151)71-155(175)103(159)35-23-19-27-39-147-67-99(135-143-147)75-183-123-115(171)111(167)107(163)79(3)187-123/h53-68,77-80,105-116,121-124,161-176H,17-52,69-76H2,1-16H3/t77-,78-,79-,80-,105+,106+,107+,108+,109+,110+,111+,112+,113-,114-,115-,116-,121+,122+,123+,124+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50466360
(CHEMBL4289617)Show SMILES NS(=O)(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C27H30N6O4S/c28-38(36,37)22-7-4-19(5-8-22)2-1-3-24-26(34)31-25-18-20(6-9-23(25)30-24)27(35)33-16-14-32(15-17-33)21-10-12-29-13-11-21/h4-13,18,24,30H,1-3,14-17H2,(H,31,34)(H2,28,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50466360
(CHEMBL4289617)Show SMILES NS(=O)(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C27H30N6O4S/c28-38(36,37)22-7-4-19(5-8-22)2-1-3-24-26(34)31-25-18-20(6-9-23(25)30-24)27(35)33-16-14-32(15-17-33)21-10-12-29-13-11-21/h4-13,18,24,30H,1-3,14-17H2,(H,31,34)(H2,28,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology
Curated by ChEMBL
| Assay Description
Inhibition of DC-SIGN (unknown origin) after 1 hr by fluorescence analysis |
Bioorg Med Chem 26: 5229-5238 (2018)
Article DOI: 10.1016/j.bmc.2018.09.024
BindingDB Entry DOI: 10.7270/Q2RV0RC3 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50466360
(CHEMBL4289617)Show SMILES NS(=O)(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C27H30N6O4S/c28-38(36,37)22-7-4-19(5-8-22)2-1-3-24-26(34)31-25-18-20(6-9-23(25)30-24)27(35)33-16-14-32(15-17-33)21-10-12-29-13-11-21/h4-13,18,24,30H,1-3,14-17H2,(H,31,34)(H2,28,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50466360
(CHEMBL4289617)Show SMILES NS(=O)(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C27H30N6O4S/c28-38(36,37)22-7-4-19(5-8-22)2-1-3-24-26(34)31-25-18-20(6-9-23(25)30-24)27(35)33-16-14-32(15-17-33)21-10-12-29-13-11-21/h4-13,18,24,30H,1-3,14-17H2,(H,31,34)(H2,28,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580864
(CHEMBL5077032)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3cc(cc2sc2cc(cc(sc4cc(cc(sc5cc(cc(s3)c5OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn3)C(C)(C)C)c4OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn4cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn4)nn3)C(C)(C)C)c2OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 602 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509061
(CHEMBL4554703)Show SMILES CC(C)(C)c1cc2Cc3cc(cc(Cc4cc(cc(Cc5cc(cc(Cc(c1)c2OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)nn2)nn1)c5OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)nn2)nn1)C(C)(C)C)c4OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)nn2)nn1)C(C)(C)C)c3OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)nn2)nn1)C(C)(C)C |r| Show InChI InChI=1S/C128H188N28O36/c1-125(2,3)85-49-77-45-79-51-86(126(4,5)6)53-81(118(79)182-42-26-38-150-58-90(130-138-150)66-154(178)102(162)30-18-14-22-34-146-62-94(134-142-146)74-186-122-114(174)110(170)106(166)98(70-158)190-122)47-83-55-88(128(10,11)12)56-84(120(83)184-44-28-40-152-60-92(132-140-152)68-156(180)104(164)32-20-16-24-36-148-64-96(136-144-148)76-188-124-116(176)112(172)108(168)100(72-160)192-124)48-82-54-87(127(7,8)9)52-80(119(82)183-43-27-39-151-59-91(131-139-151)67-155(179)103(163)31-19-15-23-35-147-63-95(135-143-147)75-187-123-115(175)111(171)107(167)99(71-159)191-123)46-78(50-85)117(77)181-41-25-37-149-57-89(129-137-149)65-153(177)101(161)29-17-13-21-33-145-61-93(133-141-145)73-185-121-113(173)109(169)105(165)97(69-157)189-121/h49-64,97-100,105-116,121-124,157-160,165-180H,13-48,65-76H2,1-12H3/t97-,98-,99-,100-,105-,106-,107-,108-,109+,110+,111+,112+,113+,114+,115+,116+,121+,122+,123+,124+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 634 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580861
(CHEMBL5079779)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3Cc4cc(cc(Cc5cc(cc(Cc6cc(cc(Cc2cc(c3)C(C)(C)C)c6OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn3)nn2)C(C)(C)C)c5OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn3)nn2)C(C)(C)C)c4OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 777 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombina... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580864
(CHEMBL5077032)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3cc(cc2sc2cc(cc(sc4cc(cc(sc5cc(cc(s3)c5OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn3)C(C)(C)C)c4OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn4cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn4)nn3)C(C)(C)C)c2OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombina... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5268319
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50536324
(CHEMBL4072223)Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(cc2)N(C)C)n1 Show InChI InChI=1S/C18H21N5OS2/c1-5-15(24)22-18-19-11(2)16(26-18)14-10-25-17(21-14)20-12-6-8-13(9-7-12)23(3)4/h6-10H,5H2,1-4H3,(H,20,21)(H,19,22,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50517251
(CHEMBL1503347)Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccc2NC(CSCc3ccccc3C)C(=O)Nc2c1 Show InChI InChI=1S/C29H32N4O3S/c1-20-7-3-4-8-22(20)18-37-19-25-28(34)31-24-17-21(11-12-23(24)30-25)29(35)33-15-13-32(14-16-33)26-9-5-6-10-27(26)36-2/h3-12,17,25,30H,13-16,18-19H2,1-2H3,(H,31,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50517251
(CHEMBL1503347)Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccc2NC(CSCc3ccccc3C)C(=O)Nc2c1 Show InChI InChI=1S/C29H32N4O3S/c1-20-7-3-4-8-22(20)18-37-19-25-28(34)31-24-17-21(11-12-23(24)30-25)29(35)33-15-13-32(14-16-33)26-9-5-6-10-27(26)36-2/h3-12,17,25,30H,13-16,18-19H2,1-2H3,(H,31,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50517251
(CHEMBL1503347)Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccc2NC(CSCc3ccccc3C)C(=O)Nc2c1 Show InChI InChI=1S/C29H32N4O3S/c1-20-7-3-4-8-22(20)18-37-19-25-28(34)31-24-17-21(11-12-23(24)30-25)29(35)33-15-13-32(14-16-33)26-9-5-6-10-27(26)36-2/h3-12,17,25,30H,13-16,18-19H2,1-2H3,(H,31,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5275742
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50591756
(CHEMBL5194701)Show SMILES NC(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ncccn2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50591756
(CHEMBL5194701)Show SMILES NC(=O)c1ccc(CCCC2Nc3ccc(cc3NC2=O)C(=O)N2CCN(CC2)c2ncccn2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5270980
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5276990
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5268319
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5268319
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5288093
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5268209
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580862
(CHEMBL5080461)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3cc(cc2sc2cc(cc(sc4cc(cc(sc5cc(cc(s3)c5OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn5cc(CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)nn5)nn3)C(C)(C)C)c4OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn4cc(CO[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)nn4)nn3)C(C)(C)C)c2OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580864
(CHEMBL5077032)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3cc(cc2sc2cc(cc(sc4cc(cc(sc5cc(cc(s3)c5OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn3)C(C)(C)C)c4OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn4cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn4)nn3)C(C)(C)C)c2OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580861
(CHEMBL5079779)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3Cc4cc(cc(Cc5cc(cc(Cc6cc(cc(Cc2cc(c3)C(C)(C)C)c6OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn3)nn2)C(C)(C)C)c5OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn3)nn2)C(C)(C)C)c4OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509063
(CHEMBL4515649)Show SMILES C[C@@H]1O[C@@H](OCc2cn(CCCCCC(=O)N(O)Cc3cn(CCCOc4c5Cc6cc(cc(Cc7cc(cc(Cc8cc(cc(Cc4cc(c5)C(C)(C)C)c8OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]8O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]8O)nn5)nn4)C(C)(C)C)c7OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]7O)nn5)nn4)C(C)(C)C)c6OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn4)C(C)(C)C)nn3)nn2)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C128H188N28O32/c1-77-105(161)109(165)113(169)121(185-77)181-73-97-65-145(141-133-97)37-25-17-21-33-101(157)153(173)69-93-61-149(137-129-93)41-29-45-177-117-81-49-83-55-90(126(8,9)10)57-85(118(83)178-46-30-42-150-62-94(130-138-150)70-154(174)102(158)34-22-18-26-38-146-66-98(134-142-146)74-182-122-114(170)110(166)106(162)78(2)186-122)51-87-59-92(128(14,15)16)60-88(120(87)180-48-32-44-152-64-96(132-140-152)72-156(176)104(160)36-24-20-28-40-148-68-100(136-144-148)76-184-124-116(172)112(168)108(164)80(4)188-124)52-86-58-91(127(11,12)13)56-84(50-82(117)54-89(53-81)125(5,6)7)119(86)179-47-31-43-151-63-95(131-139-151)71-155(175)103(159)35-23-19-27-39-147-67-99(135-143-147)75-183-123-115(171)111(167)107(163)79(3)187-123/h53-68,77-80,105-116,121-124,161-176H,17-52,69-76H2,1-16H3/t77-,78-,79-,80-,105+,106+,107+,108+,109+,110+,111+,112+,113-,114-,115-,116-,121+,122+,123+,124+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5287689
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50509061
(CHEMBL4554703)Show SMILES CC(C)(C)c1cc2Cc3cc(cc(Cc4cc(cc(Cc5cc(cc(Cc(c1)c2OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)nn2)nn1)c5OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)nn2)nn1)C(C)(C)C)c4OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)nn2)nn1)C(C)(C)C)c3OCCCn1cc(CN(O)C(=O)CCCCCn2cc(CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)nn2)nn1)C(C)(C)C |r| Show InChI InChI=1S/C128H188N28O36/c1-125(2,3)85-49-77-45-79-51-86(126(4,5)6)53-81(118(79)182-42-26-38-150-58-90(130-138-150)66-154(178)102(162)30-18-14-22-34-146-62-94(134-142-146)74-186-122-114(174)110(170)106(166)98(70-158)190-122)47-83-55-88(128(10,11)12)56-84(120(83)184-44-28-40-152-60-92(132-140-152)68-156(180)104(164)32-20-16-24-36-148-64-96(136-144-148)76-188-124-116(176)112(172)108(168)100(72-160)192-124)48-82-54-87(127(7,8)9)52-80(119(82)183-43-27-39-151-59-91(131-139-151)67-155(179)103(163)31-19-15-23-35-147-63-95(135-143-147)75-187-123-115(175)111(171)107(167)99(71-159)191-123)46-78(50-85)117(77)181-41-25-37-149-57-89(129-137-149)65-153(177)101(161)29-17-13-21-33-145-61-93(133-141-145)73-185-121-113(173)109(169)105(165)97(69-157)189-121/h49-64,97-100,105-116,121-124,157-160,165-180H,13-48,65-76H2,1-12H3/t97-,98-,99-,100-,105-,106-,107-,108-,109+,110+,111+,112+,113+,114+,115+,116+,121+,122+,123+,124+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448390
(CHEMBL3121711)Show SMILES OC[C@H]1O[C@H](OC(COc2cccc3ccccc23)COc2cccc3ccccc23)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C29H30O8/c30-15-25-26(31)27(32)28(33)29(37-25)36-20(16-34-23-13-5-9-18-7-1-3-11-21(18)23)17-35-24-14-6-10-19-8-2-4-12-22(19)24/h1-14,20,25-33H,15-17H2/t25-,26-,27+,28+,29+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50580863
(CHEMBL5070715)Show SMILES COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3Cc4cc(cc(Cc5cc(cc(Cc6cc(cc(Cc2cc(c3)C(C)(C)C)c6OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)nn3)nn2)C(C)(C)C)c5OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)nn3)nn2)C(C)(C)C)c4OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)nn1 |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00818
BindingDB Entry DOI: 10.7270/Q2474FR1 |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448389
(CHEMBL3121712)Show SMILES COc1ccc2ccc(OCC(COc3ccc4ccc(OC)cc4c3)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc2c1 |r| Show InChI InChI=1S/C31H34O10/c1-36-22-7-3-18-5-9-24(13-20(18)11-22)38-16-26(40-31-30(35)29(34)28(33)27(15-32)41-31)17-39-25-10-6-19-4-8-23(37-2)12-21(19)14-25/h3-14,26-35H,15-17H2,1-2H3/t27-,28-,29+,30+,31+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50467901
(CHEMBL4283127)Show SMILES [H][C@]1(O[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2OC[C@H]2O[C@H](OC[C@H]3O[C@H](NC(=O)C[C@H](N)C(O)=O)[C@@H](O)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H](O)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C58H98N2O48/c59-11(50(90)91)1-21(68)60-49-41(88)43(103-57-48(37(84)28(75)17(7-66)100-57)108-58-47(36(83)27(74)18(8-67)101-58)107-54-40(87)33(80)24(71)14(4-63)97-54)29(76)19(94-49)9-92-51-42(89)44(104-56-46(35(82)26(73)16(6-65)99-56)106-53-39(86)32(79)23(70)13(3-62)96-53)30(77)20(102-51)10-93-55-45(34(81)25(72)15(5-64)98-55)105-52-38(85)31(78)22(69)12(2-61)95-52/h11-20,22-49,51-58,61-67,69-89H,1-10,59H2,(H,60,68)(H,90,91)/t11-,12+,13+,14+,15+,16+,17+,18+,19+,20+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,51-,52+,53+,54+,55-,56+,57+,58+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description
Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN carbohydrate binding domain (unknown origin) expressed in Escheric... |
Bioorg Med Chem 26: 5368-5377 (2018)
Article DOI: 10.1016/j.bmc.2018.08.036
BindingDB Entry DOI: 10.7270/Q26D5WQP |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5283713
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50467901
(CHEMBL4283127)Show SMILES [H][C@]1(O[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2OC[C@H]2O[C@H](OC[C@H]3O[C@H](NC(=O)C[C@H](N)C(O)=O)[C@@H](O)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H](O)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C58H98N2O48/c59-11(50(90)91)1-21(68)60-49-41(88)43(103-57-48(37(84)28(75)17(7-66)100-57)108-58-47(36(83)27(74)18(8-67)101-58)107-54-40(87)33(80)24(71)14(4-63)97-54)29(76)19(94-49)9-92-51-42(89)44(104-56-46(35(82)26(73)16(6-65)99-56)106-53-39(86)32(79)23(70)13(3-62)96-53)30(77)20(102-51)10-93-55-45(34(81)25(72)15(5-64)98-55)105-52-38(85)31(78)22(69)12(2-61)95-52/h11-20,22-49,51-58,61-67,69-89H,1-10,59H2,(H,60,68)(H,90,91)/t11-,12+,13+,14+,15+,16+,17+,18+,19+,20+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,51-,52+,53+,54+,55-,56+,57+,58+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description
Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia col... |
Bioorg Med Chem 26: 5368-5377 (2018)
Article DOI: 10.1016/j.bmc.2018.08.036
BindingDB Entry DOI: 10.7270/Q26D5WQP |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5279021
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 2.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | BDBM50448401
(CHEMBL3121700)Show SMILES OC[C@H]1O[C@H](O[C@H]2C[C@@H]([C@H](C[C@@H]2OCCN=[N+]=[N-])C(=O)NCc2ccc(CO)cc2)C(=O)NCc2ccc(CO)cc2)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C32H43N5O11/c33-37-36-9-10-46-24-11-22(30(44)34-13-18-1-5-20(15-38)6-2-18)23(31(45)35-14-19-3-7-21(16-39)8-4-19)12-25(24)47-32-29(43)28(42)27(41)26(17-40)48-32/h1-8,22-29,32,38-43H,9-17H2,(H,34,44)(H,35,45)/t22-,23-,24-,25-,26+,27+,28-,29-,32-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| | n/a | n/a | 3.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448401
(CHEMBL3121700)Show SMILES OC[C@H]1O[C@H](O[C@H]2C[C@@H]([C@H](C[C@@H]2OCCN=[N+]=[N-])C(=O)NCc2ccc(CO)cc2)C(=O)NCc2ccc(CO)cc2)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C32H43N5O11/c33-37-36-9-10-46-24-11-22(30(44)34-13-18-1-5-20(15-38)6-2-18)23(31(45)35-14-19-3-7-21(16-39)8-4-19)12-25(24)47-32-29(43)28(42)27(41)26(17-40)48-32/h1-8,22-29,32,38-43H,9-17H2,(H,34,44)(H,35,45)/t22-,23-,24-,25-,26+,27+,28-,29-,32-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Antagonist activity at DC-SIGN receptor (unknown origin) assessed as inhibition of mannosylated BSA binding by SPR assay |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5274423
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5267284
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448382
(CHEMBL3121719)Show SMILES OC[C@H]1O[C@H](OCC(COc2ccc3ccccc3c2)Oc2ccc3ccccc3c2)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C29H30O8/c30-15-25-26(31)27(32)28(33)29(37-25)35-17-24(36-23-12-10-19-6-2-4-8-21(19)14-23)16-34-22-11-9-18-5-1-3-7-20(18)13-22/h1-14,24-33H,15-17H2/t24?,25-,26-,27+,28+,29+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448401
(CHEMBL3121700)Show SMILES OC[C@H]1O[C@H](O[C@H]2C[C@@H]([C@H](C[C@@H]2OCCN=[N+]=[N-])C(=O)NCc2ccc(CO)cc2)C(=O)NCc2ccc(CO)cc2)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C32H43N5O11/c33-37-36-9-10-46-24-11-22(30(44)34-13-18-1-5-20(15-38)6-2-18)23(31(45)35-14-19-3-7-21(16-39)8-4-19)12-25(24)47-32-29(43)28(42)27(41)26(17-40)48-32/h1-8,22-29,32,38-43H,9-17H2,(H,34,44)(H,35,45)/t22-,23-,24-,25-,26+,27+,28-,29-,32-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50467902
(CHEMBL4294737)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)\C=N\O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C38H61N11O17/c1-5-16(2)26(47-33(60)22(13-51)44-25(54)11-42-66-38-30(57)29(56)28(55)24(14-52)65-38)35(62)48-27(18(4)53)36(63)45-20(9-19-10-40-15-41-19)32(59)43-17(3)37(64)49-8-6-7-23(49)34(61)46-21(12-50)31(39)58/h10-11,15-18,20-24,26-30,38,50-53,55-57H,5-9,12-14H2,1-4H3,(H2,39,58)(H,40,41)(H,43,59)(H,44,54)(H,45,63)(H,46,61)(H,47,60)(H,48,62)/b42-11+/t16-,17-,18+,20-,21-,22-,23-,24+,26-,27-,28+,29-,30-,38+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description
Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN carbohydrate binding domain (unknown origin) expressed in Escheric... |
Bioorg Med Chem 26: 5368-5377 (2018)
Article DOI: 10.1016/j.bmc.2018.08.036
BindingDB Entry DOI: 10.7270/Q26D5WQP |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member M
(Homo sapiens) | CHEMBL5276974
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 4.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448384
(CHEMBL3121717)Show SMILES OC[C@H]1O[C@H](OCC(COc2cccc3ccccc23)Oc2cccc3ccccc23)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C29H30O8/c30-15-25-26(31)27(32)28(33)29(37-25)35-17-20(36-24-14-6-10-19-8-2-4-12-22(19)24)16-34-23-13-5-9-18-7-1-3-11-21(18)23/h1-14,20,25-33H,15-17H2/t20?,25-,26-,27+,28+,29+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448383
(CHEMBL3121718)Show SMILES COc1ccc2ccc(OCC(CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)Oc3ccc4ccc(OC)cc4c3)cc2c1 |r| Show InChI InChI=1S/C31H34O10/c1-36-22-7-3-18-5-9-24(13-20(18)11-22)38-16-26(17-39-31-30(35)29(34)28(33)27(15-32)41-31)40-25-10-6-19-4-8-23(37-2)12-21(19)14-25/h3-14,26-35H,15-17H2,1-2H3/t26?,27-,28-,29+,30+,31+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
More data for this
Ligand-Target Pair | |
CD209 antigen
(Homo sapiens (Human)) | BDBM50448391
(CHEMBL3121710)Show SMILES OC[C@H]1O[C@H](OC(COc2ccc(cc2)[N+]([O-])=O)COc2ccc(cc2)[N+]([O-])=O)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C21H24N2O12/c24-9-17-18(25)19(26)20(27)21(35-17)34-16(10-32-14-5-1-12(2-6-14)22(28)29)11-33-15-7-3-13(4-8-15)23(30)31/h1-8,16-21,24-27H,9-11H2/t17-,18-,19+,20+,21+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description
Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive... |
Eur J Med Chem 75: 308-26 (2014)
Article DOI: 10.1016/j.ejmech.2014.01.047
BindingDB Entry DOI: 10.7270/Q29K4CQR |
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Ligand-Target Pair | |
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