Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adrenocorticotropic hormone receptor (Homo sapiens (Human)) | BDBM50169442 ((1R,4S,6R)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition concentration (binding affinity) against human melanocortin receptor 2 by displacement of [125I]NDP-alpha-MSH from the human receptors exp... | Bioorg Med Chem Lett 15: 3501-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.109 BindingDB Entry DOI: 10.7270/Q2Q81CKF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50029747 ((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50134488 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50134486 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50119368 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair |