Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Methionyl-tRNA synthetase '   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553183 (CHEMBL4791458) Show SMILES CCn1c(Cc2ccc(Cl)cc2Cl)cn(Cc2nc3nc(Cl)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553184 (CHEMBL4781504) Show SMILES CCn1c(Cc2ccc(Cl)cc2Cl)cn(Cc2nc3nc(F)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553185 (CHEMBL4742903) Show SMILES FC(F)Cn1c(Cc2ccc(Cl)cc2Cl)cn(Cc2nc3nc(Cl)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553186 (CHEMBL4777699) Show SMILES FC(F)Cn1c(Cc2ccc(Cl)cc2Cl)cn(Cc2nc3nc(F)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	175	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553187 (CHEMBL4761163) Show SMILES CCCn1c(Cc2ccc(Cl)cc2Cl)cn(Cc2nc3nc(F)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM23447 (2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitroph...) Show SMILES OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553189 (CHEMBL4762630) Show SMILES CCn1c(Cc2ccc(OC)cc2Cl)cn(Cc2nc3nc(F)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553190 (CHEMBL4740481) Show SMILES COc1cc(c(Cl)cc1Cl)-c1cccc2nc(Cc3nc4nc(Cl)ccc4[nH]3)cn12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	507	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553191 (CHEMBL4745092) Show SMILES COc1cc(Cl)c(cc1OC)-c1cccc2nc(Cc3nc4nc(Cl)ccc4[nH]3)cn12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	478	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553192 (CHEMBL4750041) Show SMILES COc1cc(c(Cl)cc1Cl)-c1cccc2nc(Cc3nc4nc(F)ccc4[nH]3)cn12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553193 (CHEMBL4795266) Show SMILES COc1cc(Cl)c(cc1OC)-c1cccc2nc(Cc3nc4nc(F)ccc4[nH]3)cn12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, mitochondrial (Homo sapiens)	BDBM50553188 (CHEMBL4757779) Show SMILES CCn1c(Cc2ccc(OC)cc2Cl)cn(Cc2nc3nc(Cl)ccc3[nH]2)c1=O Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA				Citation and Details Article DOI: 10.1039/d0md00057d BindingDB Entry DOI: 10.7270/Q2SQ942Z
					More data for this Ligand-Target Pair