Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM23620 (2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cells | Mol Pharmacol 63: 1094-103 (2003) BindingDB Entry DOI: 10.7270/Q2KH0PMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM50017103 (9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenyli...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cells | Mol Pharmacol 63: 1094-103 (2003) BindingDB Entry DOI: 10.7270/Q2KH0PMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cells | Mol Pharmacol 63: 1094-103 (2003) BindingDB Entry DOI: 10.7270/Q2KH0PMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM50017691 (CHEMBL126075 | dilazep) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cells | Mol Pharmacol 63: 1094-103 (2003) BindingDB Entry DOI: 10.7270/Q2KH0PMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cells | Mol Pharmacol 63: 1094-103 (2003) BindingDB Entry DOI: 10.7270/Q2KH0PMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM50237626 (Anturan | Anturane | CHEBI:9342 | Sulfinpyrazone |...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Netherlands Cancer Institute Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PMEA efflux (PMEA: 1 uM) in MRP5-expressing MDCKII cells | Proc Natl Acad Sci U S A 97: 7476-81 (2000) Article DOI: 10.1073/pnas.120159197 BindingDB Entry DOI: 10.7270/Q20C4ZN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM54115 (5-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 65.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Troms£ Curated by ChEMBL | Assay Description Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint... | J Med Chem 55: 3049-57 (2012) Article DOI: 10.1021/jm2014666 BindingDB Entry DOI: 10.7270/Q2SX6F89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM50386476 (CHEMBL2047880) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 75.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Troms£ Curated by ChEMBL | Assay Description Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint... | J Med Chem 55: 3049-57 (2012) Article DOI: 10.1021/jm2014666 BindingDB Entry DOI: 10.7270/Q2SX6F89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 5 (Homo sapiens (Human)) | BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Troms£ Curated by ChEMBL | Assay Description Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint... | J Med Chem 55: 3049-57 (2012) Article DOI: 10.1021/jm2014666 BindingDB Entry DOI: 10.7270/Q2SX6F89 | |||||||||||
More data for this Ligand-Target Pair |