Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50266764 (CHEMBL475957 | Compound ID 5824 | N-(3,4-dichlorop...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318660 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98089 (1-[4-[(3,4-dichlorophenyl)sulfonylamino]phenyl]-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98138 (1-[4-[(4-methoxyphenyl)sulfonylamino]phenyl]-3-(4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98099 (1-[4-[(4-ethylphenyl)sulfonylamino]phenyl]-3-(3-ni...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98161 (1-[4-[[4-(aminomethyl)phenyl]sulfonylamino]phenyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318661 (CHEMBL1084867 | N-(2-Chloro-phenyl)-3-(4-{[3-(2-ch...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318661 (CHEMBL1084867 | N-(2-Chloro-phenyl)-3-(4-{[3-(2-ch...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98122 (1-(4-nitrophenyl)-3-[4-[[2-(trifluoromethyl)phenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 8.00E+3 | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98092 (1-(4-nitrophenyl)-3-[4-(o-tolylsulfonylamino)pheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98113 (1-[4-[(2-chlorophenyl)sulfonylamino]phenyl]-3-(4-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.73E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98117 (1-[4-[(3-chlorophenyl)sulfonylamino]phenyl]-3-(3-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98116 (1-[4-[(3-chlorophenyl)sulfonylamino]phenyl]-3-(4-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98095 (1-[4-(m-tolylsulfonylamino)phenyl]-3-(4-nitropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.99E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98114 (1-[4-[(2-chlorophenyl)sulfonylamino]phenyl]-3-(3-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98104 (1-[4-[(2-fluorophenyl)sulfonylamino]phenyl]-3-(4-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.22E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 9.00E+3 | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98135 (1-[4-[(3-methoxyphenyl)sulfonylamino]phenyl]-3-(4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318659 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98125 (1-(4-nitrophenyl)-3-[4-[[3-(trifluoromethyl)phenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.67E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318657 ((E)-2-(3,5-dibromo-4-methylphenylamino)-N'-(1-(2,4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318658 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98107 (1-[4-[(3-fluorophenyl)sulfonylamino]phenyl]-3-(4-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.58E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 1.80E+4 | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98109 (1-[4-[(3-fluorophenyl)sulfonylamino]phenyl]-3-(2-n...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.61E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98162 (1-[4-[[4-(aminomethyl)phenyl]sulfonylamino]phenyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.12E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81361 (NadD inhibitor 3_23 | US8785499, 3_23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.50E+4 | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98158 (1-[4-[[3-(aminomethyl)phenyl]sulfonylamino]phenyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.46E+4 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81362 (NadD inhibitor 15_11 | US8785499, 15_11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318656 ((E)-N-(4-bromophenyl)-4-(2-(4-fluorobenzylidene)hy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98151 (3-[[4-[(3-nitrophenyl)carbamoylamino]phenyl]sulfam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98152 (3-[[4-[(2-nitrophenyl)carbamoylamino]phenyl]sulfam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98153 (4-[[4-[(4-nitrophenyl)carbamoylamino]phenyl]sulfam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98154 (4-[[4-[(3-nitrophenyl)carbamoylamino]phenyl]sulfam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98155 (4-[[4-[(2-nitrophenyl)carbamoylamino]phenyl]sulfam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM98156 (1-[4-[[2-(aminomethyl)phenyl]sulfonylamino]phenyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 0 |
University of Alabama at Birmingham | Assay Description Inhibitory concentration of the compound measured against B. anthracis Nicotinic acid mononucleotide adenylyltransferase (NaMNAT)using HPLC Enzyme As... | J Comb Chem 11: 617-25 (2009) Article DOI: 10.1021/cc9000357 BindingDB Entry DOI: 10.7270/Q2K35S9C | |||||||||||
More data for this Ligand-Target Pair |
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