Compile Data Set for Download or QSAR

Found 103 hits Enz. Inhib. hit(s) with Target = 'Peptide deformylase mitochondrial'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50121444 ((R)-2-Butyl-N*1*-((S)-1-dimethylcarbamoyl-2,2-dime...) Show SMILES CCCC[C@H](CC(=O)NO)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H31N3O4/c1-7-8-9-11(10-12(20)18-23)14(21)17-13(16(2,3)4)15(22)19(5)6/h11,13,23H,7-10H2,1-6H3,(H,17,21)(H,18,20)/t11-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coli				Bioorg Med Chem Lett 12: 3595-9 (2002) BindingDB Entry DOI: 10.7270/Q2FJ2G4H
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Senju Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration required against peptide deformylase (PDF)				Bioorg Med Chem Lett 13: 3273-6 (2003) BindingDB Entry DOI: 10.7270/Q2FN15MQ
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542135 (CHEMBL4637933) Show SMILES Cc1cnc(NC(=O)[C@@H]2CC3(CC3)CN2C(=O)[C@H](CC2CCCC2)CC(=O)NO)s1 |r| Show InChI InChI=1S/C21H30N4O4S/c1-13-11-22-20(30-13)23-18(27)16-10-21(6-7-21)12-25(16)19(28)15(9-17(26)24-29)8-14-4-2-3-5-14/h11,14-16,29H,2-10,12H2,1H3,(H,24,26)(H,22,23,27)/t15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542142 (CHEMBL4638057) Show SMILES Cc1csc(NC(=O)[C@@H]2CC3(CC3)CN2C(=O)[C@H](CC2CCCC2)CC(=O)NO)n1 |r| Show InChI InChI=1S/C21H30N4O4S/c1-13-11-30-20(22-13)23-18(27)16-10-21(6-7-21)12-25(16)19(28)15(9-17(26)24-29)8-14-4-2-3-5-14/h11,14-16,29H,2-10,12H2,1H3,(H,24,26)(H,22,23,27)/t15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542149 (CHEMBL4632607) Show SMILES Cc1ccc(NC(=O)[C@@H]2CC3(CC3)CN2C(=O)[C@H](CC2CCCC2)CC(=O)NO)cc1 |r| Show InChI InChI=1S/C24H33N3O4/c1-16-6-8-19(9-7-16)25-22(29)20-14-24(10-11-24)15-27(20)23(30)18(13-21(28)26-31)12-17-4-2-3-5-17/h6-9,17-18,20,31H,2-5,10-15H2,1H3,(H,25,29)(H,26,28)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542152 (CHEMBL4641062) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccccc1 |r| Show InChI InChI=1S/C24H30N4O4/c29-20(26-31)13-18(12-16-6-4-5-7-16)23(30)28-15-24(10-11-24)14-19(28)22-25-21(27-32-22)17-8-2-1-3-9-17/h1-3,8-9,16,18-19,31H,4-7,10-15H2,(H,26,29)/t18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542164 (CHEMBL4635911) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C25H28F4N4O4/c26-16-5-6-17(18(11-16)25(27,28)29)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542158 (CHEMBL4643984) Show SMILES CCCCc1ccc(cc1)-c1noc(n1)[C@@H]1CC2(CC2)CN1C(=O)[C@H](CC1CCCC1)CC(=O)NO |r| Show InChI InChI=1S/C28H38N4O4/c1-2-3-6-19-9-11-21(12-10-19)25-29-26(36-31-25)23-17-28(13-14-28)18-32(23)27(34)22(16-24(33)30-35)15-20-7-4-5-8-20/h9-12,20,22-23,35H,2-8,13-18H2,1H3,(H,30,33)/t22-,23+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542138 (CHEMBL4639327) Show SMILES CCCC[C@H](CC(=O)NO)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cn1 |r| Show InChI InChI=1S/C20H27FN4O4/c1-2-3-4-13(9-17(26)24-29)19(28)25-12-20(7-8-20)10-15(25)18(27)23-16-6-5-14(21)11-22-16/h5-6,11,13,15,29H,2-4,7-10,12H2,1H3,(H,24,26)(H,22,23,27)/t13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542163 (CHEMBL4649534) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C25H28F4N4O4/c26-18-11-16(25(27,28)29)5-6-17(18)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542154 (CHEMBL4641416) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cn1 |r| Show InChI InChI=1S/C23H28FN5O4/c24-16-5-6-17(25-12-16)20-26-21(33-28-20)18-11-23(7-8-23)13-29(18)22(31)15(10-19(30)27-32)9-14-3-1-2-4-14/h5-6,12,14-15,18,32H,1-4,7-11,13H2,(H,27,30)/t15-,18+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542159 (CHEMBL4636545) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(cc1)C1CC1 |r| Show InChI InChI=1S/C27H34N4O4/c32-23(29-34)14-21(13-17-3-1-2-4-17)26(33)31-16-27(11-12-27)15-22(31)25-28-24(30-35-25)20-9-7-19(8-10-20)18-5-6-18/h7-10,17-18,21-22,34H,1-6,11-16H2,(H,29,32)/t21-,22+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542160 (CHEMBL4643967) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(Br)cc1 |r| Show InChI InChI=1S/C24H29BrN4O4/c25-18-7-5-16(6-8-18)21-26-22(33-28-21)19-13-24(9-10-24)14-29(19)23(31)17(12-20(30)27-32)11-15-3-1-2-4-15/h5-8,15,17,19,32H,1-4,9-14H2,(H,27,30)/t17-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542147 (CHEMBL4634572) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1cnccn1 |r| Show InChI InChI=1S/C21H29N5O4/c27-18(25-30)10-15(9-14-3-1-2-4-14)20(29)26-13-21(5-6-21)11-16(26)19(28)24-17-12-22-7-8-23-17/h7-8,12,14-16,30H,1-6,9-11,13H2,(H,25,27)(H,23,24,28)/t15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542136 (CHEMBL4636221) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cn1 |r| Show InChI InChI=1S/C22H29FN4O4/c23-16-5-6-18(24-12-16)25-20(29)17-11-22(7-8-22)13-27(17)21(30)15(10-19(28)26-31)9-14-3-1-2-4-14/h5-6,12,14-15,17,31H,1-4,7-11,13H2,(H,26,28)(H,24,25,29)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131303 ((S)-2-[(R)-2-Cyclohexylmethyl-3-(formyl-hydroxy-am...) Show SMILES CN(C)C(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)CN(O)C=O)C(C)(C)C Show InChI InChI=1S/C19H35N3O4/c1-19(2,3)16(18(25)21(4)5)20-17(24)15(12-22(26)13-23)11-14-9-7-6-8-10-14/h13-16,26H,6-12H2,1-5H3,(H,20,24)/t15-,16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542150 (CHEMBL4637166) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(Br)cc1 |r| Show InChI InChI=1S/C23H30BrN3O4/c24-17-5-7-18(8-6-17)25-21(29)19-13-23(9-10-23)14-27(19)22(30)16(12-20(28)26-31)11-15-3-1-2-4-15/h5-8,15-16,19,31H,1-4,9-14H2,(H,25,29)(H,26,28)/t16-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542148 (CHEMBL4640974) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C23H31N3O4/c27-20(25-30)13-17(12-16-6-4-5-7-16)22(29)26-15-23(10-11-23)14-19(26)21(28)24-18-8-2-1-3-9-18/h1-3,8-9,16-17,19,30H,4-7,10-15H2,(H,24,28)(H,25,27)/t17-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542162 (CHEMBL4645966) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(cc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H28ClF3N4O4/c26-18-11-16(25(27,28)29)5-6-17(18)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542151 (CHEMBL4635093) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C24H29F4N3O4/c25-16-5-6-18(17(11-16)24(26,27)28)29-21(33)19-12-23(7-8-23)13-31(19)22(34)15(10-20(32)30-35)9-14-3-1-2-4-14/h5-6,11,14-15,19,35H,1-4,7-10,12-13H2,(H,29,33)(H,30,32)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50104501 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...) Show SMILES CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H31N3O4/c1-7-8-9-12(10-19(23)11-20)14(21)17-13(16(2,3)4)15(22)18(5)6/h11-13,23H,7-10H2,1-6H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coli				Bioorg Med Chem Lett 12: 3595-9 (2002) BindingDB Entry DOI: 10.7270/Q2FJ2G4H
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50104501 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...) Show SMILES CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H31N3O4/c1-7-8-9-12(10-19(23)11-20)14(21)17-13(16(2,3)4)15(22)18(5)6/h11-13,23H,7-10H2,1-6H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50104501 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...) Show SMILES CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H31N3O4/c1-7-8-9-12(10-19(23)11-20)14(21)17-13(16(2,3)4)15(22)18(5)6/h11-13,23H,7-10H2,1-6H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Antibacterial activity of the compound against E. coli Peptide deformylase. Ni				Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542165 (CHEMBL4637631) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C24H27F3N4O4/c25-15-9-16(20(27)17(26)10-15)21-28-22(35-30-21)18-11-24(5-6-24)12-31(18)23(33)14(8-19(32)29-34)7-13-3-1-2-4-13/h9-10,13-14,18,34H,1-8,11-12H2,(H,29,32)/t14-,18+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542161 (CHEMBL4635263) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C25H29F3N4O4/c26-25(27,28)18-7-5-16(6-8-18)21-29-22(36-31-21)19-13-24(9-10-24)14-32(19)23(34)17(12-20(33)30-35)11-15-3-1-2-4-15/h5-8,15,17,19,35H,1-4,9-14H2,(H,30,33)/t17-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542141 (CHEMBL4642360) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC(=C)C[C@H]1C(=O)Nc1ccc(F)cn1 |r| Show InChI InChI=1S/C21H27FN4O4/c1-13-8-17(20(28)24-18-7-6-16(22)11-23-18)26(12-13)21(29)15(10-19(27)25-30)9-14-4-2-3-5-14/h6-7,11,14-15,17,30H,1-5,8-10,12H2,(H,25,27)(H,23,24,28)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131290 ((S)-2-[(R)-2-Cyclopentylmethyl-3-(formyl-hydroxy-a...) Show SMILES CN(C)C(=O)[C@@H](NC(=O)[C@H](CC1CCCC1)CN(O)C=O)C(C)(C)C Show InChI InChI=1S/C18H33N3O4/c1-18(2,3)15(17(24)20(4)5)19-16(23)14(11-21(25)12-22)10-13-8-6-7-9-13/h12-15,25H,6-11H2,1-5H3,(H,19,23)/t14-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542143 (CHEMBL4645936) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1nccs1 |r| Show InChI InChI=1S/C20H28N4O4S/c25-16(23-28)10-14(9-13-3-1-2-4-13)18(27)24-12-20(5-6-20)11-15(24)17(26)22-19-21-7-8-29-19/h7-8,13-15,28H,1-6,9-12H2,(H,23,25)(H,21,22,26)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542157 (CHEMBL4646467) Show SMILES CCc1ccc(cc1)-c1noc(n1)[C@@H]1CC2(CC2)CN1C(=O)[C@H](CC1CCCC1)CC(=O)NO |r| Show InChI InChI=1S/C26H34N4O4/c1-2-17-7-9-19(10-8-17)23-27-24(34-29-23)21-15-26(11-12-26)16-30(21)25(32)20(14-22(31)28-33)13-18-5-3-4-6-18/h7-10,18,20-21,33H,2-6,11-16H2,1H3,(H,28,31)/t20-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542139 (CHEMBL4641901) Show SMILES Cc1cnc(NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC2CCCC2)CC(=O)NO)s1 |r| Show InChI InChI=1S/C19H28N4O4S/c1-12-11-20-19(28-12)21-17(25)15-7-4-8-23(15)18(26)14(10-16(24)22-27)9-13-5-2-3-6-13/h11,13-15,27H,2-10H2,1H3,(H,22,24)(H,20,21,25)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542156 (CHEMBL4640884) Show SMILES Cc1ccc(cc1)-c1noc(n1)[C@@H]1CC2(CC2)CN1C(=O)[C@H](CC1CCCC1)CC(=O)NO |r| Show InChI InChI=1S/C25H32N4O4/c1-16-6-8-18(9-7-16)22-26-23(33-28-22)20-14-25(10-11-25)15-29(20)24(31)19(13-21(30)27-32)12-17-4-2-3-5-17/h6-9,17,19-20,32H,2-5,10-15H2,1H3,(H,27,30)/t19-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542137 (CHEMBL4644600) Show SMILES CCCC[C@H](CC(=O)NO)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ncc(C)s1 |r| Show InChI InChI=1S/C19H28N4O4S/c1-3-4-5-13(8-15(24)22-27)17(26)23-11-19(6-7-19)9-14(23)16(25)21-18-20-10-12(2)28-18/h10,13-14,27H,3-9,11H2,1-2H3,(H,22,24)(H,20,21,25)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542146 (CHEMBL4638180) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccncn1 |r| Show InChI InChI=1S/C21H29N5O4/c27-18(25-30)10-15(9-14-3-1-2-4-14)20(29)26-12-21(6-7-21)11-16(26)19(28)24-17-5-8-22-13-23-17/h5,8,13-16,30H,1-4,6-7,9-12H2,(H,25,27)(H,22,23,24,28)/t15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131304 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-heptanoic ac...) Show SMILES CCCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C17H33N3O4/c1-7-8-9-10-13(11-20(24)12-21)15(22)18-14(17(2,3)4)16(23)19(5)6/h12-14,24H,7-11H2,1-6H3,(H,18,22)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Antibacterial activity of the compound against E. coli Peptide deformylase. Ni				Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131292 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pen...) Show SMILES CC(C)C[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H31N3O4/c1-11(2)8-12(9-19(23)10-20)14(21)17-13(16(3,4)5)15(22)18(6)7/h10-13,23H,8-9H2,1-7H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542140 (CHEMBL4636076) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CCC[C@H]1C(=O)Nc1ccc(F)cn1 |r| Show InChI InChI=1S/C20H27FN4O4/c21-15-7-8-17(22-12-15)23-19(27)16-6-3-9-25(16)20(28)14(11-18(26)24-29)10-13-4-1-2-5-13/h7-8,12-14,16,29H,1-6,9-11H2,(H,24,26)(H,22,23,27)/t14-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542144 (CHEMBL4645201) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1cccnn1 |r| Show InChI InChI=1S/C21H29N5O4/c27-18(25-30)11-15(10-14-4-1-2-5-14)20(29)26-13-21(7-8-21)12-16(26)19(28)23-17-6-3-9-22-24-17/h3,6,9,14-16,30H,1-2,4-5,7-8,10-13H2,(H,25,27)(H,23,24,28)/t15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542155 (CHEMBL4643686) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1cnccn1 |r| Show InChI InChI=1S/C22H28N6O4/c29-18(26-31)10-15(9-14-3-1-2-4-14)21(30)28-13-22(5-6-22)11-17(28)20-25-19(27-32-20)16-12-23-7-8-24-16/h7-8,12,14-15,17,31H,1-6,9-11,13H2,(H,26,29)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131302 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-5-methyl-hex...) Show SMILES CC(C)CC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C17H33N3O4/c1-12(2)8-9-13(10-20(24)11-21)15(22)18-14(17(3,4)5)16(23)19(6)7/h11-14,24H,8-10H2,1-7H3,(H,18,22)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131295 ((S)-2-[(R)-2-Ethylsulfanylmethyl-3-(formyl-hydroxy...) Show SMILES CCSC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C15H29N3O4S/c1-7-23-9-11(8-18(22)10-19)13(20)16-12(15(2,3)4)14(21)17(5)6/h10-12,22H,7-9H2,1-6H3,(H,16,20)/t11-,12+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131307 ((S)-2-[(R)-2-Cyclopentyl-3-(formyl-hydroxy-amino)-...) Show SMILES CN(C)C(=O)[C@@H](NC(=O)[C@@H](CN(O)C=O)C1CCCC1)C(C)(C)C Show InChI InChI=1S/C17H31N3O4/c1-17(2,3)14(16(23)19(4)5)18-15(22)13(10-20(24)11-21)12-8-6-7-9-12/h11-14,24H,6-10H2,1-5H3,(H,18,22)/t13-,14+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131288 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-hex-5-enoic ...) Show SMILES CN(C)C(=O)[C@@H](NC(=O)[C@H](CCC=C)CN(O)C=O)C(C)(C)C Show InChI InChI=1S/C16H29N3O4/c1-7-8-9-12(10-19(23)11-20)14(21)17-13(16(2,3)4)15(22)18(5)6/h7,11-13,23H,1,8-10H2,2-6H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131301 ((S)-2-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-propi...) Show SMILES CN(C)C(=O)[C@@H](NC(=O)[C@@H](CN(O)C=O)Cc1ccccc1)C(C)(C)C Show InChI InChI=1S/C19H29N3O4/c1-19(2,3)16(18(25)21(4)5)20-17(24)15(12-22(26)13-23)11-14-9-7-6-8-10-14/h6-10,13,15-16,26H,11-12H2,1-5H3,(H,20,24)/t15-,16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542153 (CHEMBL4649755) Show SMILES Cc1noc(n1)[C@@H]1CC2(CC2)CN1C(=O)[C@H](CC1CCCC1)CC(=O)NO |r| Show InChI InChI=1S/C19H28N4O4/c1-12-20-17(27-22-12)15-10-19(6-7-19)11-23(15)18(25)14(9-16(24)21-26)8-13-4-2-3-5-13/h13-15,26H,2-11H2,1H3,(H,21,24)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131291 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-octanoic aci...) Show SMILES CCCCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C18H35N3O4/c1-7-8-9-10-11-14(12-21(25)13-22)16(23)19-15(18(2,3)4)17(24)20(5)6/h13-15,25H,7-12H2,1-6H3,(H,19,23)/t14-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50131296 ((R)-2-[(Formyl-hydroxy-amino)-methyl]-hex-4-ynoic ...) Show SMILES CC#CC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C Show InChI InChI=1S/C16H27N3O4/c1-7-8-9-12(10-19(23)11-20)14(21)17-13(16(2,3)4)15(22)18(5)6/h11-13,23H,9-10H2,1-6H3,(H,17,21)/t12-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
British Biotech Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition against Escherichia coli peptide deformylase				Bioorg Med Chem Lett 13: 2709-13 (2003) BindingDB Entry DOI: 10.7270/Q2XW4J6S
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50542145 (CHEMBL4641571) Show SMILES Cn1cc(NC(=O)[C@@H]2CC3(CC3)CN2C(=O)[C@H](CC2CCCC2)CC(=O)NO)cn1 |r| Show InChI InChI=1S/C21H31N5O4/c1-25-12-16(11-22-25)23-19(28)17-10-21(6-7-21)13-26(17)20(29)15(9-18(27)24-30)8-14-4-2-3-5-14/h11-12,14-15,17,30H,2-10,13H2,1H3,(H,23,28)(H,24,27)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF using N-formylated peptide as substrate in presence of NAD+ by formate dehydrogenase-coupled spectrophotometric assay				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50594242 (CHEMBL5191348) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@@H]1CO |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00123 BindingDB Entry DOI: 10.7270/Q2B56PRV
					More data for this Ligand-Target Pair

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