Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50280172 (1,3,4-Trihydroxy-5-phosphonomethyl-cyclohexanecarb...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibitory activity against calf thymus ribonucleotide reductase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM93206 (2,4,5-trihydroxy-6-(phosphonatomethyl)oxane-2-carb...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University | Assay Description Enzyme inhibition using dehydroquinate synthase. | Biochemistry 28: 7572-82 (1989) Article DOI: 10.1021/bi00445a011 BindingDB Entry DOI: 10.7270/Q24J0CRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthase | J Med Chem 24: 496-9 (1981) BindingDB Entry DOI: 10.7270/Q2K64JTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100860 (3,4-Dihydroxy-5-phosphonomethyl-benzoic acid | CHE...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028883 ((1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100862 (3,4-Dihydroxy-5-(2-phosphono-ethyl)-benzoic acid |...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100862 (3,4-Dihydroxy-5-(2-phosphono-ethyl)-benzoic acid |...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100860 (3,4-Dihydroxy-5-phosphonomethyl-benzoic acid | CHE...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM93205 (4,5-dihydroxy-6-(phosphonatomethyl)oxane-2-carboxy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University | Assay Description Enzyme inhibition using dehydroquinate synthase. | Biochemistry 28: 7572-82 (1989) Article DOI: 10.1021/bi00445a011 BindingDB Entry DOI: 10.7270/Q24J0CRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100861 (3,4-Dihydroxybenzoate, VIII | 3,4-dihydroxybenzoic...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100861 (3,4-Dihydroxybenzoate, VIII | 3,4-dihydroxybenzoic...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100859 (CHEMBL440285 | [2-(2,3-Dihydroxy-phenyl)-ethyl]-ph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50100859 (CHEMBL440285 | [2-(2,3-Dihydroxy-phenyl)-ethyl]-ph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM26188 (α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 6.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM26188 (α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 8.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University Curated by ChEMBL | Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli | Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028883 ((1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028883 ((1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000540 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50280172 (1,3,4-Trihydroxy-5-phosphonomethyl-cyclohexanecarb...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000750 | 1.40E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50280172 (1,3,4-Trihydroxy-5-phosphonomethyl-cyclohexanecarb...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000750 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-dehydroquinate synthase (Escherichia coli (strain K12)) | BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000320 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase | Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21 | |||||||||||
More data for this Ligand-Target Pair |