BindingDB PrimarySearch

Found 33 hits Enz. Inhib. hit(s) with Target = 'Carbonyl reductase [NADPH] 1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50247677 ((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM8726 (5-chloro-2-(2,4-dichlorophenoxy)phenol \| CHEMBL849...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one \| 5,7-dihy...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50073099 ((9E,11E)-(4R,6R,8R)-16-chloro-17,19-dihydroxy-4-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50096619 (1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM9461 (5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...) Show SMILES COc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543400 (CHEMBL4640248) Show SMILES Oc1cccc2cc(C(=O)Nc3ccccc3Cl)c(=N)oc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543404 (CHEMBL4640154) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543405 (CHEMBL4639417) Show SMILES Oc1cccc2cc(C(=O)Nc3cccc(Cl)c3)c(=N)oc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50247677 ((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543397 (CHEMBL4646593) Show SMILES CCc1cccc(NC(=O)c2cc3cccc(O)c3oc2=N)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543399 (CHEMBL4648793) Show SMILES Cc1ccc(NC(=O)c2cc3cccc(O)c3oc2=N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543402 (CHEMBL4634960) Show SMILES Oc1cccc2cc(C(=O)Nc3cccc(F)c3)c(=N)oc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM8726 (5-chloro-2-(2,4-dichlorophenoxy)phenol \| CHEMBL849...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543401 (CHEMBL4644092) Show SMILES Oc1cccc2cc(C(=O)Nc3ccc(F)cc3)c(=N)oc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one \| 5,7-dihy...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308752 (3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES CC(C)(C)N1NC(c2c1ncnc2N)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiol				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308752 (3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...) Show SMILES CC(C)(C)N1NC(c2c1ncnc2N)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	788	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiol				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50241828 (CHEMBL4089817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Binding affinity against high affinity component of Adenosine A1 receptor from rat brain membranes using [3H]-DPCPX				J Med Chem 60: 8441-8455 (2017) Article DOI: 10.1021/acs.jmedchem.7b00830 BindingDB Entry DOI: 10.7270/Q2NZ89S7
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308753 (3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50073099 ((9E,11E)-(4R,6R,8R)-16-chloro-17,19-dihydroxy-4-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50096619 (1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308751 (3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308750 (3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50241817 (CHEMBL4081954) Show SMILES Oc1ccc(CCCNC(=O)c2cc3ccc(O)cc3oc2=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human CBR1 using isatin as substrate				J Med Chem 60: 8441-8455 (2017) Article DOI: 10.1021/acs.jmedchem.7b00830 BindingDB Entry DOI: 10.7270/Q2NZ89S7
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308754 (3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308750 (3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM9461 (5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...) Show SMILES COc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308751 (3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308753 (3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308754 (3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
Howard University Curated by ChEMBL					More data for this Ligand-Target Pair