BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Inositol Triphosphate'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (RAT)	BDBM84745 (CAS_136434-34-9 \| DULOXETINE \| LY-248686 \| LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP K_i Database									Neuropsychopharmacology 25: 871-80 (2001) Article DOI: 10.1016/S0893-133X(01)00298-6 BindingDB Entry DOI: 10.7270/Q25M648W
Lilly Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (RAT)	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP K_i Database									Neuropsychopharmacology 27: 699-711 (2002) Article DOI: 10.1016/S0893-133X(02)00346-9 BindingDB Entry DOI: 10.7270/Q2GQ6W98
Lilly Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (RAT)	BDBM82071 (CAS_93413-69-5 \| CAS_99300-78-4 \| NSC_62923 \| VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP K_i Database									Neuropsychopharmacology 25: 871-80 (2001) Article DOI: 10.1016/S0893-133X(01)00298-6 BindingDB Entry DOI: 10.7270/Q25M648W
Lilly Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Inositol-tetrakisphosphate 1-kinase (Homo sapiens (Human))	BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) Show SMILES CN1CCC[C@H]1c1cc(C)no1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 310-8 (1994) BindingDB Entry DOI: 10.7270/Q2HH6HKJ
Abbott Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (RAT)	BDBM50010685 ((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by PDSP K_i Database									J Pharmacol Exp Ther 262: 383-93 (1992) BindingDB Entry DOI: 10.7270/Q218350W
University of North Carolina Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Inositol-tetrakisphosphate 1-kinase (Homo sapiens (Human))	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine \| 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP K_i Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
Abbott Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair