Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018839 (CHEMBL3286829) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) by off-chip mobility shift assay | J Med Chem 57: 4720-44 (2014) Article DOI: 10.1021/jm500261q BindingDB Entry DOI: 10.7270/Q2K35W68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018815 (CHEMBL3286820) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) by off-chip mobility shift assay | J Med Chem 57: 4720-44 (2014) Article DOI: 10.1021/jm500261q BindingDB Entry DOI: 10.7270/Q2K35W68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50584720 (CHEMBL5088153) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to TrkB (unknown origin) assessed as inhibition constant by radiometric assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01597 BindingDB Entry DOI: 10.7270/Q2377DMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018830 (CHEMBL3286830 | US10543199, Compound PF-06463922 |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Taibah University Curated by ChEMBL | Assay Description Inhibition of TrkB (unknown origin) | Eur J Med Chem 134: 348-356 (2017) Article DOI: 10.1016/j.ejmech.2017.04.032 BindingDB Entry DOI: 10.7270/Q2154KR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018830 (CHEMBL3286830 | US10543199, Compound PF-06463922 |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) by off-chip mobility shift assay | J Med Chem 57: 4720-44 (2014) Article DOI: 10.1021/jm500261q BindingDB Entry DOI: 10.7270/Q2K35W68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018842 (CHEMBL3286832) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) by off-chip mobility shift assay | J Med Chem 57: 4720-44 (2014) Article DOI: 10.1021/jm500261q BindingDB Entry DOI: 10.7270/Q2K35W68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50018841 (CHEMBL3286831) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 77 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) by off-chip mobility shift assay | J Med Chem 57: 4720-44 (2014) Article DOI: 10.1021/jm500261q BindingDB Entry DOI: 10.7270/Q2K35W68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50402020 (CHEMBL2205426) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of recombinant TRKB after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP | Bioorg Med Chem Lett 22: 7615-22 (2012) Article DOI: 10.1016/j.bmcl.2012.10.009 BindingDB Entry DOI: 10.7270/Q2XK8GQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50224883 (7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of TRKB | Bioorg Med Chem Lett 17: 6593-601 (2007) Article DOI: 10.1016/j.bmcl.2007.09.063 BindingDB Entry DOI: 10.7270/Q2X067WT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM374727 ((7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14- tetrah...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00712 BindingDB Entry DOI: 10.7270/Q27W6H3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0640 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assay | Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0930 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assay | Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164901 (US10166239, Ex. 3-15 | US11406644, Example 3-15 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164901 (US10166239, Ex. 3-15 | US11406644, Example 3-15 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164901 (US10166239, Ex. 3-15 | US11406644, Example 3-15 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164901 (US10166239, Ex. 3-15 | US11406644, Example 3-15 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164945 (US10166239, Ex. 3-40-5 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164943 (US10166239, Ex. 3-40-3 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164941 (US10166239, Ex. 3-40-1 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164931 (US10166239, Ex. 3-35-5 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164930 (US10166239, Ex. 3-35-4 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164928 (US10166239, Ex. 3-35-2 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164902 (US10166239, Ex. 3-16 | US11406644, Example 3-16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164930 (US10166239, Ex. 3-35-4 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164945 (US10166239, Ex. 3-40-5 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164943 (US10166239, Ex. 3-40-3 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164941 (US10166239, Ex. 3-40-1 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164931 (US10166239, Ex. 3-35-5 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164930 (US10166239, Ex. 3-35-4 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164928 (US10166239, Ex. 3-35-2 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GENZYME CORPORATION US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50512464 (CHEMBL4555442) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human GST-tagged TRKB (456 to 822) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min... | Bioorg Med Chem Lett 29: 2320-2326 (2019) Article DOI: 10.1016/j.bmcl.2019.06.018 BindingDB Entry DOI: 10.7270/Q2X351R6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164945 (US10166239, Ex. 3-40-5 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164943 (US10166239, Ex. 3-40-3 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164941 (US10166239, Ex. 3-40-1 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164931 (US10166239, Ex. 3-35-5 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164930 (US10166239, Ex. 3-35-4 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164928 (US10166239, Ex. 3-35-2 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164945 (US10166239, Ex. 3-40-5 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164943 (US10166239, Ex. 3-40-3 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164941 (US10166239, Ex. 3-40-1 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164931 (US10166239, Ex. 3-35-5 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164902 (US10166239, Ex. 3-16 | US11406644, Example 3-16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164928 (US10166239, Ex. 3-35-2 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164902 (US10166239, Ex. 3-16 | US11406644, Example 3-16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164902 (US10166239, Ex. 3-16 | US11406644, Example 3-16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164927 (US10166239, Ex. 3-35-1 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164927 (US10166239, Ex. 3-35-1 | US11406644, Example 3-35-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation US Patent | Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ... | US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM164944 (US10166239, Ex. 3-40-4 | US11406644, Example 3-40-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Genzyme Corporation US Patent | Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter... | US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB | |||||||||||
More data for this Ligand-Target Pair |
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