Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'Nicotinamidase (BbNic)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM50026863 (CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...) Show SMILES O=Cc1cccnc1 Show InChI InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92852 (Nicotinamidase Inhibitor, 19) Show SMILES Cc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO/c1-6-2-7(5-9)4-8-3-6/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92850 (Nicotinamidase Inhibitor, 17) Show SMILES Brc1cncc(C=O)c1 Show InChI InChI=1S/C6H4BrNO/c7-6-1-5(4-9)2-8-3-6/h1-4H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92854 (Nicotinamidase Inhibitor, 21) Show SMILES Fc1ccc(C=O)cn1 Show InChI InChI=1S/C6H4FNO/c7-6-2-1-5(4-9)3-8-6/h1-4H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92855 (Nicotinamidase Inhibitor, 22) Show SMILES COc1ccncc1C=O Show InChI InChI=1S/C7H7NO2/c1-10-7-2-3-8-4-6(7)5-9/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.53E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92857 (Nicotinamidase Inhibitor, 24) Show SMILES CC(=O)c1cccnc1 Show InChI InChI=1S/C7H7NO/c1-6(9)7-3-2-4-8-5-7/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	3.42E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92853 (Nicotinamidase Inhibitor, 20) Show SMILES Clc1ncccc1C=O Show InChI InChI=1S/C6H4ClNO/c7-6-5(4-9)2-1-3-8-6/h1-4H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	3.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Pyrazinamidase/nicotinamidase, PncA protein (Borrelia burgdorferi)	BDBM92856 (Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5) Show SMILES N#Cc1cccnc1 Show InChI InChI=1S/C6H4N2/c7-4-6-2-1-3-8-5-6/h1-3,5H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair