BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Prohormone convertase 1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50303774 (CHEMBL566340 \| phenylacetyl-Arg-Val-Arg-4-amidinob...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
Philipps University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50303775 ((S)-2-acetamido-N-((S)-1-((S)-1-(4-carbamimidoylbe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
Philipps University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50533413 (CHEMBL3126388) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre Hospitalier Universitaire Vaudois (CHUV) Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal truncated human SPC3 expressed in drosophila Schneider 2 cells after 1 hr by spectrofluorometry				J Med Chem 59: 7719-37 (2016) Article DOI: 10.1021/acs.jmedchem.5b01516 BindingDB Entry DOI: 10.7270/Q2M048X4
					More data for this Ligand-Target Pair
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50303776 (CHEMBL568525 \| N-((6S,9S,12S)-1,17-diamino-6-(4-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
Philipps University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50303777 ((S)-5-guanidino-N-((S)-1-((S)-5-guanidino-1-(3-gua...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
Philipps University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuroendocrine convertase 1 (Homo sapiens (Human))	BDBM50303778 ((S)-N-((1-carbamimidoylpiperidin-4-yl)methyl)-5-gu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
Philipps University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair