Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Prolyl 4-hydroxylase alpha-1 subunit'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM26106 (CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...) Show SMILES OC(=O)CNC(=O)C(O)=O Show InChI InChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) Show SMILES OC(=O)c1ccc(nc1)C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM26106 (CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...) Show SMILES OC(=O)CNC(=O)C(O)=O Show InChI InChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) Show SMILES OC(=O)c1ccc(nc1)C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM50000866 (2-(Oxalyl-amino)-propionic acid (0.25H2O) | CHEMBL...) Show SMILES C[C@H](NC(=O)C(O)=O)C(O)=O Show InChI InChI=1S/C5H7NO5/c1-2(4(8)9)6-3(7)5(10)11/h2H,1H3,(H,6,7)(H,8,9)(H,10,11)/t2-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM50000865 (2-(Oxalyl-amino)-propionic acid | CHEMBL314979) Show SMILES CC(NC(=O)C(O)=O)C(O)=O Show InChI InChI=1S/C5H7NO5/c1-2(4(8)9)6-3(7)5(10)11/h2H,1H3,(H,6,7)(H,8,9)(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM50000864 (CHEMBL314175 | N-(2-Methanesulfonylamino-2-oxo-eth...) Show SMILES CS(=O)(=O)NC(=O)CNC(=O)C(O)=O Show InChI InChI=1S/C5H8N2O6S/c1-14(12,13)7-3(8)2-6-4(9)5(10)11/h2H2,1H3,(H,6,9)(H,7,8)(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus)	BDBM50000863 (2-(Oxalyl-amino)-propionic acid | CHEMBL88472) Show SMILES C[C@@H](NC(=O)C(O)=O)C(O)=O Show InChI InChI=1S/C5H7NO5/c1-2(4(8)9)6-3(7)5(10)11/h2H,1H3,(H,6,7)(H,8,9)(H,10,11)/t2-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	6.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase at 50 ug/mL				J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9
					More data for this Ligand-Target Pair