Compile Data Set for Download or QSAR

Found 84 hits Enz. Inhib. hit(s) with Target = 'Ribosomal S6 Kinase 2 (RSK-2)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259863 (US9505766, 68) Show SMILES CC(C)NS(=O)(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C22H26N6O3S/c1-14(2)27-32(30,31)17(12-23)11-18-19(16-7-5-15(3)6-8-16)20-21(24)25-13-26-22(20)28(18)9-4-10-29/h5-8,11,13-14,27,29H,4,9-10H2,1-3H3,(H2,24,25,26)/b17-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259840 (US9505766, 44) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC2CC2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C23H24N6O2/c1-14-3-5-15(6-4-14)19-18(11-16(12-24)23(31)28-17-7-8-17)29(9-2-10-30)22-20(19)21(25)26-13-27-22/h3-6,11,13,17,30H,2,7-10H2,1H3,(H,28,31)(H2,25,26,27)/b16-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259876 (US9505766, 81) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]c2ccc(\C=C(/C#N)C(=O)NC(C)(C)CO)cc12 Show InChI InChI=1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,28)/b16-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259807 (US9505766, CN-NH2 (6)) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(N)=O)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C20H20N6O2/c1-12-3-5-13(6-4-12)16-15(9-14(10-21)19(23)28)26(7-2-8-27)20-17(16)18(22)24-11-25-20/h3-6,9,11,27H,2,7-8H2,1H3,(H2,23,28)(H2,22,24,25)/b14-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259861 (US9505766, 66) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC(C)(CO)CO)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H28N6O4/c1-15-4-6-16(7-5-15)19-18(10-17(11-25)23(34)29-24(2,12-32)13-33)30(8-3-9-31)22-20(19)21(26)27-14-28-22/h4-7,10,14,31-33H,3,8-9,12-13H2,1-2H3,(H,29,34)(H2,26,27,28)/b17-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259839 (US9505766, 43) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC(C)(C)CO)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H28N6O3/c1-15-5-7-16(8-6-15)19-18(11-17(12-25)23(33)29-24(2,3)13-32)30(9-4-10-31)22-20(19)21(26)27-14-28-22/h5-8,11,14,31-32H,4,9-10,13H2,1-3H3,(H,29,33)(H2,26,27,28)/b17-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM50403059 (CHEMBL2216829 | US9505766, 64) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC(C)(C)C)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H28N6O2/c1-15-6-8-16(9-7-15)19-18(12-17(13-25)23(32)29-24(2,3)4)30(10-5-11-31)22-20(19)21(26)27-14-28-22/h6-9,12,14,31H,5,10-11H2,1-4H3,(H,29,32)(H2,26,27,28)/b17-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259844 (US9505766, 48) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)N2CCC2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C23H24N6O2/c1-15-4-6-16(7-5-15)19-18(12-17(13-24)23(31)28-8-2-9-28)29(10-3-11-30)22-20(19)21(25)26-14-27-22/h4-7,12,14,30H,2-3,8-11H2,1H3,(H2,25,26,27)/b17-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259870 (US9505766, 75) Show SMILES CN(C)NC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C22H25N7O2/c1-14-5-7-15(8-6-14)18-17(11-16(12-23)22(31)27-28(2)3)29(9-4-10-30)21-19(18)20(24)25-13-26-21/h5-8,11,13,30H,4,9-10H2,1-3H3,(H,27,31)(H2,24,25,26)/b16-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259808 (US9505766, 74 | US9505766, CN-NHiPr (7)) Show SMILES CC(C)NC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C23H26N6O2/c1-14(2)28-23(31)17(12-24)11-18-19(16-7-5-15(3)6-8-16)20-21(25)26-13-27-22(20)29(18)9-4-10-30/h5-8,11,13-14,30H,4,9-10H2,1-3H3,(H,28,31)(H2,25,26,27)/b17-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259845 (US9505766, 49) Show SMILES CN(C)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C22H24N6O2/c1-14-5-7-15(8-6-14)18-17(11-16(12-23)22(30)27(2)3)28(9-4-10-29)21-19(18)20(24)25-13-26-21/h5-8,11,13,29H,4,9-10H2,1-3H3,(H2,24,25,26)/b16-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259806 (US9505766, CN-OtBu (5)) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)OC(C)(C)C)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H27N5O3/c1-15-6-8-16(9-7-15)19-18(12-17(13-25)23(31)32-24(2,3)4)29(10-5-11-30)22-20(19)21(26)27-14-28-22/h6-9,12,14,30H,5,10-11H2,1-4H3,(H2,26,27,28)/b17-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259858 (US9505766, 62) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)N2CCOCC2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H26N6O3/c1-16-3-5-17(6-4-16)20-19(13-18(14-25)24(32)29-8-11-33-12-9-29)30(7-2-10-31)23-21(20)22(26)27-15-28-23/h3-6,13,15,31H,2,7-12H2,1H3,(H2,26,27,28)/b18-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.5	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259872 (US9505766, 77) Show SMILES CONC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C21H22N6O3/c1-13-4-6-14(7-5-13)17-16(10-15(11-22)21(29)26-30-2)27(8-3-9-28)20-18(17)19(23)24-12-25-20/h4-7,10,12,28H,3,8-9H2,1-2H3,(H,26,29)(H2,23,24,25)/b15-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259805 (US9505766, CN-OMe (4)) Show SMILES COC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C21H21N5O3/c1-13-4-6-14(7-5-13)17-16(10-15(11-22)21(28)29-2)26(8-3-9-27)20-18(17)19(23)24-12-25-20/h4-7,10,12,27H,3,8-9H2,1-2H3,(H2,23,24,25)/b15-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259846 (US9505766, 50) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)N2CC(O)C2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C23H24N6O3/c1-14-3-5-15(6-4-14)19-18(9-16(10-24)23(32)28-11-17(31)12-28)29(7-2-8-30)22-20(19)21(25)26-13-27-22/h3-6,9,13,17,30-31H,2,7-8,11-12H2,1H3,(H2,25,26,27)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.2	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259836 (US9505766, 40) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]c2ccc(\C=C(/C#N)C(N)=O)cc12 Show InChI InChI=1S/C20H18N4O4/c1-26-16-8-12(9-17(27-2)19(16)28-3)18-14-7-11(4-5-15(14)23-24-18)6-13(10-21)20(22)25/h4-9H,1-3H3,(H2,22,25)(H,23,24)/b13-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259837 (US9505766, 41) Show SMILES CNC(=O)C(=C\c1ccc2[nH]nc(-c3cc(OC)c(OC)c(OC)c3)c2c1)\C#N Show InChI InChI=1S/C21H20N4O4/c1-23-21(26)14(11-22)7-12-5-6-16-15(8-12)19(25-24-16)13-9-17(27-2)20(29-4)18(10-13)28-3/h5-10H,1-4H3,(H,23,26)(H,24,25)/b14-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259862 (US9505766, 67) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)n2cncn2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C21H20N8O/c1-14-3-5-15(6-4-14)18-17(9-16(10-22)29-13-24-11-27-29)28(7-2-8-30)21-19(18)20(23)25-12-26-21/h3-6,9,11-13,30H,2,7-8H2,1H3,(H2,23,25,26)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.8	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259867 (US9505766, 72) Show SMILES CN(CCO)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C23H26N6O3/c1-15-4-6-16(7-5-15)19-18(12-17(13-24)23(32)28(2)9-11-31)29(8-3-10-30)22-20(19)21(25)26-14-27-22/h4-7,12,14,30-31H,3,8-11H2,1-2H3,(H2,25,26,27)/b17-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259875 (US9505766, 80) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)n2ccnn2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C21H20N8O/c1-14-3-5-15(6-4-14)18-17(11-16(12-22)29-9-7-26-27-29)28(8-2-10-30)21-19(18)20(23)24-13-25-21/h3-7,9,11,13,30H,2,8,10H2,1H3,(H2,23,24,25)/b16-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259842 (US9505766, 46) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)N2CCCC2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H26N6O2/c1-16-5-7-17(8-6-16)20-19(13-18(14-25)24(32)29-9-2-3-10-29)30(11-4-12-31)23-21(20)22(26)27-15-28-23/h5-8,13,15,31H,2-4,9-12H2,1H3,(H2,26,27,28)/b18-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.2	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259841 (US9505766, 45) Show SMILES CCN(CC)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C24H28N6O2/c1-4-29(5-2)24(32)18(14-25)13-19-20(17-9-7-16(3)8-10-17)21-22(26)27-15-28-23(21)30(19)11-6-12-31/h7-10,13,15,31H,4-6,11-12H2,1-3H3,(H2,26,27,28)/b18-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.3	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259868 (US9505766, 73) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC(C)(C)C(=O)OCC=C)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C27H30N6O4/c1-5-13-37-26(36)27(3,4)32-25(35)19(15-28)14-20-21(18-9-7-17(2)8-10-18)22-23(29)30-16-31-24(22)33(20)11-6-12-34/h5,7-10,14,16,34H,1,6,11-13H2,2-4H3,(H,32,35)(H2,29,30,31)/b19-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.1	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259873 (US9505766, 78) Show SMILES Cc1csc(n1)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C23H22N6OS/c1-14-4-6-16(7-5-14)19-18(10-17(11-24)23-28-15(2)12-31-23)29(8-3-9-30)22-20(19)21(25)26-13-27-22/h4-7,10,12-13,30H,3,8-9H2,1-2H3,(H2,25,26,27)/b17-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.4	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259809 (US9505766, CN-NHBn (8)) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NCc2ccccc2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C27H26N6O2/c1-18-8-10-20(11-9-18)23-22(33(12-5-13-34)26-24(23)25(29)31-17-32-26)14-21(15-28)27(35)30-16-19-6-3-2-4-7-19/h2-4,6-11,14,17,34H,5,12-13,16H2,1H3,(H,30,35)(H2,29,31,32)/b21-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259877 (US9505766, 82) Show SMILES NC(=O)C(=C\c1ccc2[nH]nc(-c3cccnc3)c2c1)\C#N Show InChI InChI=1S/C16H11N5O/c17-8-12(16(18)22)6-10-3-4-14-13(7-10)15(21-20-14)11-2-1-5-19-9-11/h1-7,9H,(H2,18,22)(H,20,21)/b12-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259860 (US9505766, 65) Show SMILES CN(C)CCN(C)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C25H31N7O2/c1-17-6-8-18(9-7-17)21-20(14-19(15-26)25(34)31(4)12-11-30(2)3)32(10-5-13-33)24-22(21)23(27)28-16-29-24/h6-9,14,16,33H,5,10-13H2,1-4H3,(H2,27,28,29)/b19-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.3	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259843 (US9505766, 47) Show SMILES CN1CCN(CC1)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C25H29N7O2/c1-17-4-6-18(7-5-17)21-20(14-19(15-26)25(34)31-11-9-30(2)10-12-31)32(8-3-13-33)24-22(21)23(27)28-16-29-24/h4-7,14,16,33H,3,8-13H2,1-2H3,(H2,27,28,29)/b19-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.3	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259859 (US9505766, 63) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)c2ccncc2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H22N6O/c1-16-3-5-18(6-4-16)21-20(13-19(14-25)17-7-9-27-10-8-17)30(11-2-12-31)24-22(21)23(26)28-15-29-24/h3-10,13,15,31H,2,11-12H2,1H3,(H2,26,28,29)/b19-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259802 (US9505766, Me enone (1)) Show SMILES CC(=O)\C=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO Show InChI InChI=1S/C20H22N4O2/c1-13-4-7-15(8-5-13)17-16(9-6-14(2)26)24(10-3-11-25)20-18(17)19(21)22-12-23-20/h4-9,12,25H,3,10-11H2,1-2H3,(H2,21,22,23)/b9-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259838 (US9505766, 42) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]c2ccc(\C=C(/C#N)C(=O)N(C)C)cc12 Show InChI InChI=1S/C22H22N4O4/c1-26(2)22(27)15(12-23)8-13-6-7-17-16(9-13)20(25-24-17)14-10-18(28-3)21(30-5)19(11-14)29-4/h6-11H,1-5H3,(H,24,25)/b15-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259816 (US9505766, 16) Show SMILES CNC(=O)C(=C\c1ccc2cn[nH]c2c1)\C#N Show InChI InChI=1S/C12H10N4O/c1-14-12(17)10(6-13)4-8-2-3-9-7-15-16-11(9)5-8/h2-5,7H,1H3,(H,14,17)(H,15,16)/b10-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259812 (US9505766, 12) Show SMILES NC(=O)C(=C\c1cccc(c1)C(=O)c1c[nH]c2ncccc12)\C#N Show InChI InChI=1S/C18H12N4O2/c19-9-13(17(20)24)8-11-3-1-4-12(7-11)16(23)15-10-22-18-14(15)5-2-6-21-18/h1-8,10H,(H2,20,24)(H,21,22)/b13-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259830 (US9505766, 34) Show SMILES CNC(=O)C(=C\c1ccc2[nH]ncc2c1)\C#N Show InChI InChI=1S/C12H10N4O/c1-14-12(17)9(6-13)4-8-2-3-11-10(5-8)7-15-16-11/h2-5,7H,1H3,(H,14,17)(H,15,16)/b9-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	129	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259828 (US9505766, 32) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)c2ccccn2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H22N6O/c1-16-6-8-17(9-7-16)21-20(13-18(14-25)19-5-2-3-10-27-19)30(11-4-12-31)24-22(21)23(26)28-15-29-24/h2-3,5-10,13,15,31H,4,11-12H2,1H3,(H2,26,28,29)/b18-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259815 (US9505766, 15) Show SMILES NC(=O)C(=C\c1ccc2cn[nH]c2c1)\C#N Show InChI InChI=1S/C11H8N4O/c12-5-9(11(13)16)3-7-1-2-8-6-14-15-10(8)4-7/h1-4,6H,(H2,13,16)(H,14,15)/b9-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	183	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740,C436V] (Homo sapiens (Human))	BDBM259804 (US9505766, Me acrylate (2)) Show SMILES COC(=O)\C=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO Show InChI InChI=1S/C20H22N4O3/c1-13-4-6-14(7-5-13)17-15(8-9-16(26)27-2)24(10-3-11-25)20-18(17)19(21)22-12-23-20/h4-9,12,25H,3,10-11H2,1-2H3,(H2,21,22,23)/b9-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259871 (US9505766, 76) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)c2cccnc2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H22N6O/c1-16-5-7-17(8-6-16)21-20(12-19(13-25)18-4-2-9-27-14-18)30(10-3-11-31)24-22(21)23(26)28-15-29-24/h2,4-9,12,14-15,31H,3,10-11H2,1H3,(H2,26,28,29)/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	224	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259804 (US9505766, Me acrylate (2)) Show SMILES COC(=O)\C=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO Show InChI InChI=1S/C20H22N4O3/c1-13-4-6-14(7-5-13)17-15(8-9-16(26)27-2)24(10-3-11-25)20-18(17)19(21)22-12-23-20/h4-9,12,25H,3,10-11H2,1-2H3,(H2,21,22,23)/b9-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259813 (US9505766, 13) Show SMILES NC(=O)C(=C\c1ccc2[nH]ncc2c1)\C#N Show InChI InChI=1S/C11H8N4O/c12-5-8(11(13)16)3-7-1-2-10-9(4-7)6-14-15-10/h1-4,6H,(H2,13,16)(H,14,15)/b8-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259874 (US9505766, 79) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)n2cccn2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C22H21N7O/c1-15-4-6-16(7-5-15)19-18(12-17(13-23)29-10-2-8-27-29)28(9-3-11-30)22-20(19)21(24)25-14-26-22/h2,4-8,10,12,14,30H,3,9,11H2,1H3,(H2,24,25,26)/b17-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	274	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259834 (US9505766, 38) Show SMILES CNC(=O)C(=C\c1cccc(c1)C(=O)c1c[nH]c2ncccc12)\C#N Show InChI InChI=1S/C19H14N4O2/c1-21-19(25)14(10-20)9-12-4-2-5-13(8-12)17(24)16-11-23-18-15(16)6-3-7-22-18/h2-9,11H,1H3,(H,21,25)(H,22,23)/b14-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	386	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259831 (US9505766, 35) Show SMILES CC(C)NC(=O)C(=C\c1ccc2[nH]ncc2c1)\C#N Show InChI InChI=1S/C14H14N4O/c1-9(2)17-14(19)11(7-15)5-10-3-4-13-12(6-10)8-16-18-13/h3-6,8-9H,1-2H3,(H,16,18)(H,17,19)/b11-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	493	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259865 (US9505766, 70) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC23CC4CC(CC(C4)C2)C3)n(CCCO)c2ncnc(N)c12 |TLB:23:22:25:19.18.17,23:18:25:22.24.21,THB:15:16:19:22.23.21,24:22:19:25.16.17,24:16:19:22.23.21| Show InChI InChI=1S/C30H34N6O2/c1-18-3-5-22(6-4-18)25-24(36(7-2-8-37)28-26(25)27(32)33-17-34-28)12-23(16-31)29(38)35-30-13-19-9-20(14-30)11-21(10-19)15-30/h3-6,12,17,19-21,37H,2,7-11,13-15H2,1H3,(H,35,38)(H2,32,33,34)/b23-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259808 (US9505766, 74 | US9505766, CN-NHiPr (7)) Show SMILES CC(C)NC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N Show InChI InChI=1S/C23H26N6O2/c1-14(2)28-23(31)17(12-24)11-18-19(16-7-5-15(3)6-8-16)20-21(25)26-13-27-22(20)29(18)9-4-10-30/h5-8,11,13-14,30H,4,9-10H2,1-3H3,(H,28,31)(H2,25,26,27)/b17-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259866 (US9505766, 71) Show SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)c2cc[n+]([O-])cc2)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C24H22N6O2/c1-16-3-5-18(6-4-16)21-20(13-19(14-25)17-7-10-29(32)11-8-17)30(9-2-12-31)24-22(21)23(26)27-15-28-24/h3-8,10-11,13,15,31H,2,9,12H2,1H3,(H2,26,27,28)/b19-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259864 (US9505766, 69) Show SMILES Cc1ccc(cc1)-c1c(C(=O)C(F)F)n(CCCO)c2ncnc(N)c12 Show InChI InChI=1S/C18H18F2N4O2/c1-10-3-5-11(6-4-10)12-13-17(21)22-9-23-18(13)24(7-2-8-25)14(12)15(26)16(19)20/h3-6,9,16,25H,2,7-8H2,1H3,(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259817 (US9505766, 17) Show SMILES CC(C)NC(=O)C(=C\c1ccc2cn[nH]c2c1)\C#N Show InChI InChI=1S/C14H14N4O/c1-9(2)17-14(19)12(7-15)5-10-3-4-11-8-16-18-13(11)6-10/h3-6,8-9H,1-2H3,(H,16,18)(H,17,19)/b12-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 [399-740] (Homo sapiens (Human))	BDBM259833 (US9505766, 37) Show SMILES CN(C)C(=O)C(=C\c1ccc2[nH]ncc2c1)\C#N Show InChI InChI=1S/C13H12N4O/c1-17(2)13(18)10(7-14)5-9-3-4-12-11(6-9)8-15-16-12/h3-6,8H,1-2H3,(H,15,16)/b10-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	747	n/a	n/a	n/a	n/a	8.0	22
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 84 total )  |  Next  |  Last  >>

Jump to: