BindingDB PrimarySearch

Found 1 hit Enz. Inhib. hit(s) with Target = 'Caseinolytic protein C1 (ClpC1 NTD E89Q)'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,E89Q] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	65	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair