Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ETS-related transcription factor Elf-3/Vitamin D3 receptor-interacting protein (ESX/MED23)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mediator of RNA polymerase II transcription subunit 23 (Homo sapiens (Human))	BDBM50396057 (CHEMBL2170196) Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc2c(OCC(O)CN(CCCCCN)C(=O)N3CCC(CC3)C3CCN(CC3)C(=O)C34CC5CC(CC(C5)C3)C4)cccc12 |TLB:41:43:46:50.48.49,THB:48:47:44:50.49.51,48:49:46.47.52:44,51:49:46:52.43.44,51:43:46:50.48.49| Show InChI InChI=1S/C45H63N5O6S/c1-32-8-10-39(11-9-32)57(54,55)50-23-16-40-41(50)6-5-7-42(40)56-31-38(51)30-49(18-4-2-3-17-46)44(53)48-21-14-37(15-22-48)36-12-19-47(20-13-36)43(52)45-27-33-24-34(28-45)26-35(25-33)29-45/h5-11,16,23,33-38,51H,2-4,12-15,17-22,24-31,46H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to Sur2				Eur J Med Chem 46: 1949-63 (2011) Article DOI: 10.1016/j.ejmech.2011.01.047 BindingDB Entry DOI: 10.7270/Q22808QQ
					More data for this Ligand-Target Pair