Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Forkhead box M DNA-binding domain (Foxm DBD)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218818 (CID 2753793) Show SMILES N=c1sc(nn1-c1ccccc1)C(=O)c1cccs1 Show InChI InChI=1S/C13H9N3OS2/c14-13-16(9-5-2-1-3-6-9)15-12(19-13)11(17)10-7-4-8-18-10/h1-8,14H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218821 (CID 2748293) Show SMILES CC(C)OC(=O)C1=C(C)NC(=S)NC1c1ccc(cc1)[N+]([O-])=O |c:6| Show InChI InChI=1S/C15H17N3O4S/c1-8(2)22-14(19)12-9(3)16-15(23)17-13(12)10-4-6-11(7-5-10)18(20)21/h4-8,13H,1-3H3,(H2,16,17,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218817 (CID 2748371) Show SMILES COc1ccccc1C(CCC(O)=O)C(=O)c1ccccc1OC Show InChI InChI=1S/C19H20O5/c1-23-16-9-5-3-7-13(16)14(11-12-18(20)21)19(22)15-8-4-6-10-17(15)24-2/h3-10,14H,11-12H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218820 (CID 53708511) Show SMILES CC(C)c1cc(\C=C\C(O)=O)c2cccc(C)c2c1O Show InChI InChI=1S/C17H18O3/c1-10(2)14-9-12(7-8-15(18)19)13-6-4-5-11(3)16(13)17(14)20/h4-10,20H,1-3H3,(H,18,19)/b8-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218816 (CID 2751638) Show SMILES Fc1ccc(cc1Cl)-n1c(=O)[nH]nc(-c2ccccc2)c1=S Show InChI InChI=1S/C15H9ClFN3OS/c16-11-8-10(6-7-12(11)17)20-14(22)13(18-19-15(20)21)9-4-2-1-3-5-9/h1-8H,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair
Forkhead box protein M1 [235-327] (Homo sapiens (Human))	BDBM218819 (CID 50943806) Show SMILES CCC[C@H]1C(=O)N[C@@]2([C@H](OC2=O)[C@@H]2CCCC=C2)[C@@]1(C)O |r,c:17| Show InChI InChI=1S/C16H23NO4/c1-3-7-11-13(18)17-16(15(11,2)20)12(21-14(16)19)10-8-5-4-6-9-10/h5,8,10-12,20H,3-4,6-7,9H2,1-2H3,(H,17,18)/t10-,11-,12+,15-,16+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a
Linyi People's Hospital					Assay Description The fluorescence emission spectra of tryptophan residues were used to monitor the changes in local chemical environment of protein upon ligand bindin...				Bioorg Chem 70: 12-16 (2017) Article DOI: 10.1016/j.bioorg.2016.11.003 BindingDB Entry DOI: 10.7270/Q21C1VQV
					More data for this Ligand-Target Pair