Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Inhibitor of NF-kappa-B kinase (IKK)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NF-kappa-B essential modulator (Homo sapiens (Human))	BDBM50587701 (CHEMBL5180326) Show SMILES [H][C@@]12C[C@]3([C@H](c4ccc(C)cc4)[C@@]1([H])C=C(C=O)[C@H]([C@@H]2[N+]([O-])=O)c1ccc(C)cc1)C(=O)N(C)c1ccccc31 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
NF-kappa-B essential modulator (Homo sapiens (Human))	BDBM50587700 (CHEMBL5171411) Show SMILES [H][C@@]12C[C@@]3([C@H](c4ccc(C)cc4)[C@@]1([H])C=C(C=O)[C@H]([C@@H]2[N+]([O-])=O)c1ccc(C)cc1)C(=O)N(C)c1ccccc31 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
NF-kappa-B essential modulator (Homo sapiens (Human))	BDBM50130248 (CHEMBL79004 | N-(6-Chloro-9H-beta-carbolin-8-yl)-n...) Show SMILES Clc1cc(NC(=O)c2cccnc2)c2[nH]c3cnccc3c2c1 Show InChI InChI=1S/C17H11ClN4O/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10/h1-9,21H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of GST-IkB phosphorylation by TNF-alpha stimulated HeLa cell lysate (IP-IKKgamma)				Bioorg Med Chem Lett 13: 2419-22 (2003) BindingDB Entry DOI: 10.7270/Q2PK0FJ7
					More data for this Ligand-Target Pair