Compile Data Set for Download or QSAR

Found 1251 hits Enz. Inhib. hit(s) with Target = 'Mitotic checkpoint serine/threonine-protein kinase BUB1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50076185 (CHEMBL3416026 | US9290481, 1.1) Show SMILES N[C@H]1CCCC[C@H]1Nc1nnc(C(N)=O)c(Nc2cccc3cc[nH]c23)n1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Competitive binding affinity to human BUB1				J Med Chem 58: 1950-63 (2015) Article DOI: 10.1021/jm5018863 BindingDB Entry DOI: 10.7270/Q2G44S0C
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011188 (CHEMBL3260329) Show SMILES CS(=O)(=O)CCOc1cnc(nc1Nc1ccncc1C(N)=O)-c1nn(Cc2ccccc2F)c2CCCc12 Show InChI InChI=1S/C26H26FN7O4S/c1-39(36,37)12-11-38-22-14-30-26(32-25(22)31-20-9-10-29-13-18(20)24(28)35)23-17-6-4-8-21(17)34(33-23)15-16-5-2-3-7-19(16)27/h2-3,5,7,9-10,13-14H,4,6,8,11-12,15H2,1H3,(H2,28,35)(H,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011189 (CHEMBL3260328) Show SMILES NC(=O)c1cnccc1N(CCO)c1nc(ncc1OCCO)-c1nn(Cc2ccccc2F)c2CCCc12 Show InChI InChI=1S/C27H28FN7O4/c28-20-6-2-1-4-17(20)16-35-22-7-3-5-18(22)24(33-35)26-31-15-23(39-13-12-37)27(32-26)34(10-11-36)21-8-9-30-14-19(21)25(29)38/h1-2,4,6,8-9,14-15,36-37H,3,5,7,10-13,16H2,(H2,29,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011200 (CHEMBL3260327) Show SMILES CCOC(=O)c1cnccc1Nc1nc(ncc1Oc1ccccc1C(=O)OCC)-c1nn(Cc2ccccc2F)c2CCCc12 Show InChI InChI=1S/C34H31FN6O5/c1-3-44-33(42)23-11-6-8-15-28(23)46-29-19-37-32(39-31(29)38-26-16-17-36-18-24(26)34(43)45-4-2)30-22-12-9-14-27(22)41(40-30)20-21-10-5-7-13-25(21)35/h5-8,10-11,13,15-19H,3-4,9,12,14,20H2,1-2H3,(H,36,37,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011201 (CHEMBL3260326) Show SMILES CCOc1cc(F)c(Cn2nc(c3CCCc23)-c2ncc(OCC3(CO)COC3)c(Nc3ccncc3)n2)c(F)c1 Show InChI InChI=1S/C29H30F2N6O4/c1-2-40-19-10-22(30)21(23(31)11-19)13-37-24-5-3-4-20(24)26(36-37)28-33-12-25(41-17-29(14-38)15-39-16-29)27(35-28)34-18-6-8-32-9-7-18/h6-12,38H,2-5,13-17H2,1H3,(H,32,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011202 (CHEMBL3260325) Show SMILES CCOc1cc(F)c(Cn2nc(c3CCCc23)-c2ncc(OCCN(C)C)c(Nc3ccncc3)n2)c(F)c1 Show InChI InChI=1S/C28H31F2N7O2/c1-4-38-19-14-22(29)21(23(30)15-19)17-37-24-7-5-6-20(24)26(35-37)28-32-16-25(39-13-12-36(2)3)27(34-28)33-18-8-10-31-11-9-18/h8-11,14-16H,4-7,12-13,17H2,1-3H3,(H,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50011209 (CHEMBL3260324) Show SMILES CCOc1cc(F)c(Cn2nc(c3CCCc23)-c2ncc(OC)c(Nc3ccncc3)n2)c(F)c1 Show InChI InChI=1S/C25H24F2N6O2/c1-3-35-16-11-19(26)18(20(27)12-16)14-33-21-6-4-5-17(21)23(32-33)25-29-13-22(34-2)24(31-25)30-15-7-9-28-10-8-15/h7-13H,3-6,14H2,1-2H3,(H,28,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay				ACS Med Chem Lett 5: 280-1 (2014) Article DOI: 10.1021/ml5000492 BindingDB Entry DOI: 10.7270/Q2XG9SN8
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50021626 (CHEMBL3298400) Show SMILES CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1ccsc1 Show InChI InChI=1S/C18H23N3O2S/c1-18(2,3)11-20-16(22)7-14-8-19-17(23)15-6-13(9-21(14)15)12-4-5-24-10-12/h4-6,9-10,14H,7-8,11H2,1-3H3,(H,19,23)(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50021618 (CHEMBL3297762 | US9145418, 2) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38ClN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50048357 (CHEMBL3309990) Show SMILES Nc1nc2c3c(F)cccc3nc(Cc3ccc4OCOc4c3)n2n1 Show InChI InChI=1S/C17H12FN5O2/c18-10-2-1-3-11-15(10)16-21-17(19)22-23(16)14(20-11)7-9-4-5-12-13(6-9)25-8-24-12/h1-6H,7-8H2,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 22: 4135-50 (2014) Article DOI: 10.1016/j.bmc.2014.05.056 BindingDB Entry DOI: 10.7270/Q2S46TMD
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50048362 (CHEMBL3309995) Show SMILES Nc1nc2c3ccc(N)cc3nc(Cc3ccc4OCOc4c3)n2n1 Show InChI InChI=1S/C17H14N6O2/c18-10-2-3-11-12(7-10)20-15(23-16(11)21-17(19)22-23)6-9-1-4-13-14(5-9)25-8-24-13/h1-5,7H,6,8,18H2,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 22: 4135-50 (2014) Article DOI: 10.1016/j.bmc.2014.05.056 BindingDB Entry DOI: 10.7270/Q2S46TMD
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50048364 (CHEMBL3309997) Show SMILES OCCCNc1ccc2c3ncnn3c(nc2c1)-c1ccc2OCOc2c1 Show InChI InChI=1S/C19H17N5O3/c25-7-1-6-20-13-3-4-14-15(9-13)23-18(24-19(14)21-10-22-24)12-2-5-16-17(8-12)27-11-26-16/h2-5,8-10,20,25H,1,6-7,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 22: 4135-50 (2014) Article DOI: 10.1016/j.bmc.2014.05.056 BindingDB Entry DOI: 10.7270/Q2S46TMD
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50048365 (CHEMBL3309998) Show SMILES Nc1nc2c3ccc(NCCO)cc3nc(Cc3ccc4OCOc4c3)n2n1 Show InChI InChI=1S/C19H18N6O3/c20-19-23-18-13-3-2-12(21-5-6-26)9-14(13)22-17(25(18)24-19)8-11-1-4-15-16(7-11)28-10-27-15/h1-4,7,9,21,26H,5-6,8,10H2,(H2,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 22: 4135-50 (2014) Article DOI: 10.1016/j.bmc.2014.05.056 BindingDB Entry DOI: 10.7270/Q2S46TMD
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50048374 (CHEMBL3310151) Show SMILES CN1CCN(CC1)c1cc(F)c2c3nc(N)nn3c(Cc3ccc4OCOc4c3)nc2c1 Show InChI InChI=1S/C22H22FN7O2/c1-28-4-6-29(7-5-28)14-10-15(23)20-16(11-14)25-19(30-21(20)26-22(24)27-30)9-13-2-3-17-18(8-13)32-12-31-17/h2-3,8,10-11H,4-7,9,12H2,1H3,(H2,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of BUB1 (unknown origin)				Bioorg Med Chem 22: 4135-50 (2014) Article DOI: 10.1016/j.bmc.2014.05.056 BindingDB Entry DOI: 10.7270/Q2S46TMD
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM138348 (US8877944, 99) Show SMILES NC(=O)c1cc(F)cc2CN(C3CCN(CC3)C3CCC(F)(F)CC3)C(=O)c12 Show InChI InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human BUB1				J Med Chem 58: 6875-98 (2015) Article DOI: 10.1021/acs.jmedchem.5b00680 BindingDB Entry DOI: 10.7270/Q2JD4ZKF
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM50343559 (1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...) Show SMILES CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2ncc3CCc4c(nn(CCO)c4-c3n2)C(N)=O)c1 Show InChI InChI=1S/C24H27F3N8O3/c1-33-6-8-34(9-7-33)15-3-5-18(38-24(25,26)27)17(12-15)30-23-29-13-14-2-4-16-20(22(28)37)32-35(10-11-36)21(16)19(14)31-23/h3,5,12-13,36H,2,4,6-11H2,1H3,(H2,28,37)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences srl Curated by ChEMBL					Assay Description Inhibition of BUB1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting				Bioorg Med Chem Lett 21: 2969-74 (2011) Article DOI: 10.1016/j.bmcl.2011.03.054 BindingDB Entry DOI: 10.7270/Q27M088W
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162101 (US9682995, 20) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1cnc2cc(F)ccc2n1 Show InChI InChI=1S/C21H18FN5OS/c1-3-13-6-4-5-7-15(13)25-20(28)19-12(2)27-29-21(19)26-18-11-23-17-10-14(22)8-9-16(17)24-18/h4-11H,3H2,1-2H3,(H,24,26)(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162102 (US9682995, 21) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1nc2ccccc2nc1C Show InChI InChI=1S/C22H21N5OS/c1-4-15-9-5-6-10-16(15)25-21(28)19-13(2)27-29-22(19)26-20-14(3)23-17-11-7-8-12-18(17)24-20/h5-12H,4H2,1-3H3,(H,24,26)(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162103 (US9682995, 22) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3cccc(C)c3n2)cn1 Show InChI InChI=1S/C20H18N6O2S/c1-11-5-4-6-14-18(11)24-15(10-21-14)25-20-17(12(2)26-29-20)19(27)23-13-7-8-16(28-3)22-9-13/h4-10H,1-3H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162105 (US9682995, 23) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3cc(Cl)ccc3n2)cn1 Show InChI InChI=1S/C19H15ClN6O2S/c1-10-17(18(27)23-12-4-6-16(28-2)22-8-12)19(29-26-10)25-15-9-21-14-7-11(20)3-5-13(14)24-15/h3-9H,1-2H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162106 (US9682995, 24) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2nccnc2C#N)cn1 Show InChI InChI=1S/C16H13N7O2S/c1-9-13(15(24)21-10-3-4-12(25-2)20-8-10)16(26-23-9)22-14-11(7-17)18-5-6-19-14/h3-6,8H,1-2H3,(H,19,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162108 (US9682995, 25) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cc(ccn2)C#N)cn1 Show InChI InChI=1S/C17H14N6O2S/c1-10-15(16(24)21-12-3-4-14(25-2)20-9-12)17(26-23-10)22-13-7-11(8-18)5-6-19-13/h3-7,9H,1-2H3,(H,19,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162109 (US9682995, 26) Show SMILES CCOC(=O)c1sc(Nc2snc(C)c2C(=O)Nc2ccccc2CC)nc1C Show InChI InChI=1S/C20H22N4O3S2/c1-5-13-9-7-8-10-14(13)22-17(25)15-11(3)24-29-18(15)23-20-21-12(4)16(28-20)19(26)27-6-2/h7-10H,5-6H2,1-4H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162110 (US9682995, 27) Show SMILES Cc1nsc(Nc2cc(ccn2)C#N)c1C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C17H11F2N5OS/c1-9-15(16(25)22-11-2-3-12(18)13(19)7-11)17(26-24-9)23-14-6-10(8-20)4-5-21-14/h2-7H,1H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162111 (US9682995, 28) Show SMILES Cc1nsc(Nc2ccc(cn2)C#N)c1C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C17H11F2N5OS/c1-9-15(16(25)22-11-3-4-12(18)13(19)6-11)17(26-24-9)23-14-5-2-10(7-20)8-21-14/h2-6,8H,1H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162114 (US9682995, 29) Show SMILES CCOC(=O)c1cnc(Nc2snc(C)c2C(=O)Nc2ccc(OC)nc2)s1 Show InChI InChI=1S/C17H17N5O4S2/c1-4-26-16(24)11-8-19-17(27-11)21-15-13(9(2)22-28-15)14(23)20-10-5-6-12(25-3)18-7-10/h5-8H,4H2,1-3H3,(H,19,21)(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162115 (US9682995, 30) Show SMILES CCOC(=O)c1sc(Nc2snc(C)c2C(=O)Nc2ccc(OC)nc2)nc1C Show InChI InChI=1S/C18H19N5O4S2/c1-5-27-17(25)14-10(3)20-18(28-14)22-16-13(9(2)23-29-16)15(24)21-11-6-7-12(26-4)19-8-11/h6-8H,5H2,1-4H3,(H,20,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162116 (US9682995, 31) Show SMILES COC(=O)c1ccc(Nc2snc(C)c2C(=O)Nc2ccc(OC)nc2)nc1 Show InChI InChI=1S/C18H17N5O4S/c1-10-15(16(24)21-12-5-7-14(26-2)20-9-12)17(28-23-10)22-13-6-4-11(8-19-13)18(25)27-3/h4-9H,1-3H3,(H,19,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162117 (US9682995, 32) Show SMILES COC(=O)c1cnc(Nc2snc(C)c2C(=O)Nc2ccc(OC)nc2)cn1 Show InChI InChI=1S/C17H16N6O4S/c1-9-14(15(24)21-10-4-5-13(26-2)20-6-10)16(28-23-9)22-12-8-18-11(7-19-12)17(25)27-3/h4-8H,1-3H3,(H,19,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162118 (US9682995, 33) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1cnc2cccc(C)c2n1 Show InChI InChI=1S/C22H21N5OS/c1-4-15-9-5-6-10-16(15)24-21(28)19-14(3)27-29-22(19)26-18-12-23-17-11-7-8-13(2)20(17)25-18/h5-12H,4H2,1-3H3,(H,24,28)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162119 (US9682995, 34) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1nccnc1C#N Show InChI InChI=1S/C18H16N6OS/c1-3-12-6-4-5-7-13(12)22-17(25)15-11(2)24-26-18(15)23-16-14(10-19)20-8-9-21-16/h4-9H,3H2,1-2H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162121 (US9682995, 35) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1nc(C)nc2ccccc12 Show InChI InChI=1S/C22H21N5OS/c1-4-15-9-5-7-11-17(15)25-21(28)19-13(2)27-29-22(19)26-20-16-10-6-8-12-18(16)23-14(3)24-20/h5-12H,4H2,1-3H3,(H,25,28)(H,23,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162125 (US9682995, 37) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cccc(n2)C#N)cn1 Show InChI InChI=1S/C17H14N6O2S/c1-10-15(16(24)21-12-6-7-14(25-2)19-9-12)17(26-23-10)22-13-5-3-4-11(8-18)20-13/h3-7,9H,1-2H3,(H,20,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162126 (US9682995, 38) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1nc(C)nc2sccc12 Show InChI InChI=1S/C20H19N5OS2/c1-4-13-7-5-6-8-15(13)23-18(26)16-11(2)25-28-20(16)24-17-14-9-10-27-19(14)22-12(3)21-17/h5-10H,4H2,1-3H3,(H,23,26)(H,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162131 (US9682995, 39) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2ccc(cn2)C#N)cn1 Show InChI InChI=1S/C17H14N6O2S/c1-10-15(16(24)21-12-4-6-14(25-2)20-9-12)17(26-23-10)22-13-5-3-11(7-18)8-19-13/h3-6,8-9H,1-2H3,(H,19,22)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162132 (US9682995, 40) Show SMILES Cc1nsc(Nc2cnc3ccccc3n2)c1C(=O)Nc1ccc(Cl)c(F)c1 Show InChI InChI=1S/C19H13ClFN5OS/c1-10-17(18(27)23-11-6-7-12(20)13(21)8-11)19(28-26-10)25-16-9-22-14-4-2-3-5-15(14)24-16/h2-9H,1H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162133 (US9682995, 41) Show SMILES CCc1ccccc1NC(=O)c1c(C)nsc1Nc1cnc2ccc(Cl)cc2n1 Show InChI InChI=1S/C21H18ClN5OS/c1-3-13-6-4-5-7-15(13)25-20(28)19-12(2)27-29-21(19)26-18-11-23-16-9-8-14(22)10-17(16)24-18/h4-11H,3H2,1-2H3,(H,24,26)(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162134 (US9682995, 42) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3ccc(Cl)cc3n2)cn1 Show InChI InChI=1S/C19H15ClN6O2S/c1-10-17(18(27)23-12-4-6-16(28-2)22-8-12)19(29-26-10)25-15-9-21-13-5-3-11(20)7-14(13)24-15/h3-9H,1-2H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162135 (US9682995, 43) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3c(F)c(F)ccc3n2)cn1 Show InChI InChI=1S/C19H14F2N6O2S/c1-9-15(18(28)24-10-3-6-14(29-2)22-7-10)19(30-27-9)26-13-8-23-17-12(25-13)5-4-11(20)16(17)21/h3-8H,1-2H3,(H,24,28)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162136 (US9682995, 44) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3ccc(F)cc3n2)cn1 Show InChI InChI=1S/C19H15FN6O2S/c1-10-17(18(27)23-12-4-6-16(28-2)22-8-12)19(29-26-10)25-15-9-21-13-5-3-11(20)7-14(13)24-15/h3-9H,1-2H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162137 (US9682995, 45) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2cnc3cc(ccc3n2)C(F)(F)F)cn1 Show InChI InChI=1S/C20H15F3N6O2S/c1-10-17(18(30)26-12-4-6-16(31-2)25-8-12)19(32-29-10)28-15-9-24-14-7-11(20(21,22)23)3-5-13(14)27-15/h3-9H,1-2H3,(H,26,30)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162138 (US9682995, 46) Show SMILES Cc1nsc(Nc2cnc3cc(F)ccc3n2)c1C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C19H12F3N5OS/c1-9-17(18(28)24-11-3-4-12(21)13(22)7-11)19(29-27-9)26-16-8-23-15-6-10(20)2-5-14(15)25-16/h2-8H,1H3,(H,24,28)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162143 (US9682995, 47) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2nc3c(cccc3s2)C(F)(F)F)cc1F Show InChI InChI=1S/C20H14F4N4O2S2/c1-9-15(17(29)25-10-6-7-13(30-2)12(21)8-10)18(32-28-9)27-19-26-16-11(20(22,23)24)4-3-5-14(16)31-19/h3-8H,1-2H3,(H,25,29)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162144 (US9682995, 48) Show SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2nc3c(cccc3s2)C(F)(F)F)cn1 Show InChI InChI=1S/C19H14F3N5O2S2/c1-9-14(16(28)24-10-6-7-13(29-2)23-8-10)17(31-27-9)26-18-25-15-11(19(20,21)22)4-3-5-12(15)30-18/h3-8H,1-2H3,(H,24,28)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162145 (US9682995, 49) Show SMILES CN(C)C(=O)c1cnc(Nc2snc(C)c2C(=O)Nc2ccc(F)c(F)c2)s1 Show InChI InChI=1S/C17H15F2N5O2S2/c1-8-13(14(25)21-9-4-5-10(18)11(19)6-9)15(28-23-8)22-17-20-7-12(27-17)16(26)24(2)3/h4-7H,1-3H3,(H,20,22)(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162146 (US9682995, 50) Show SMILES Cc1nsc(Nc2cnc3ccccc3n2)c1C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C19H13F2N5OS/c1-10-17(18(27)23-11-6-7-12(20)13(21)8-11)19(28-26-10)25-16-9-22-14-4-2-3-5-15(14)24-16/h2-9H,1H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162148 (US9682995, 51) Show SMILES Cc1nsc(Nc2nc3c(cccc3s2)C(F)(F)F)c1C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C19H11F5N4OS2/c1-8-14(16(29)25-9-5-6-11(20)12(21)7-9)17(31-28-8)27-18-26-15-10(19(22,23)24)3-2-4-13(15)30-18/h2-7H,1H3,(H,25,29)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162149 (US9682995, 52) Show SMILES Cc1nsc(Nc2ccc(cn2)C#N)c1C(=O)Nc1ccc(Cl)c(F)c1 Show InChI InChI=1S/C17H11ClFN5OS/c1-9-15(16(25)22-11-3-4-12(18)13(19)6-11)17(26-24-9)23-14-5-2-10(7-20)8-21-14/h2-6,8H,1H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162150 (US9682995, 53) Show SMILES Cc1nsc(Nc2nc3c(cccc3s2)C(F)(F)F)c1C(=O)Nc1ccc(Cl)c(F)c1 Show InChI InChI=1S/C19H11ClF4N4OS2/c1-8-14(16(29)25-9-5-6-11(20)12(21)7-9)17(31-28-8)27-18-26-15-10(19(22,23)24)3-2-4-13(15)30-18/h2-7H,1H3,(H,25,29)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085] (Homo sapiens (Human))	BDBM162152 (US9682995, 54) Show SMILES Cc1nsc(Nc2cc(ccn2)C#N)c1C(=O)Nc1ccc(Cl)c(F)c1 Show InChI InChI=1S/C17H11ClFN5OS/c1-9-15(16(25)22-11-2-3-12(18)13(19)7-11)17(26-24-9)23-14-6-10(8-20)4-5-21-14/h2-7H,1H3,(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...				US Patent US9682995 (2017) BindingDB Entry DOI: 10.7270/Q2WH2N5Q
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1251 total )  |  Next  |  Last  >>

Jump to: