Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | 7.5 | 5 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | 7.5 | 10 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | 7.5 | 15 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | 7.5 | 20 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | 7.5 | 25 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50017674 ((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+7 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50034220 (2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-tri...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM92471 (Sinefungin) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.15E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+6 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50041457 (4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10E+6 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair |