Compile Data Set for Download or QSAR

Found 40 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor (PDGFr)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM124970 (US8765747, 2) Show SMILES CCN1CCN(Cc2ccc(NC(=O)c3cccc(c3)-c3ccc4nc(NC(=O)C5CC5)sc4n3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C29H25F3N8OS/c1-17-34-24(16-25(35-17)40-12-10-33-11-13-40)39-28-38-23-9-8-22(37-27(23)42-28)18-4-2-5-19(14-18)26(41)36-21-7-3-6-20(15-21)29(30,31)32/h2-9,14-16,33H,10-13H2,1H3,(H,36,41)(H,34,35,38,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute, Inc. US Patent					Assay Description KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...				US Patent US8765747 (2014) BindingDB Entry DOI: 10.7270/Q2VX0F6R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290837 (4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...) Show SMILES COc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C18H18N2O5/c1-21-14-6-5-11(7-15(14)22-2)25-18-12-8-16(23-3)17(24-4)9-13(12)19-10-20-18/h5-10H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290840 (4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...) Show SMILES COc1cc2nccc(Oc3cccc(OC)c3OC)c2cc1OC Show InChI InChI=1S/C19H19NO5/c1-21-15-6-5-7-16(19(15)24-4)25-14-8-9-20-13-11-18(23-3)17(22-2)10-12(13)14/h5-11H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290841 (4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline | CHE...) Show SMILES COc1cc2nccc(Oc3cccc(F)c3)c2cc1OC Show InChI InChI=1S/C17H14FNO3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290842 (6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline | CH...) Show SMILES COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C18H17NO4/c1-20-12-4-6-13(7-5-12)23-16-8-9-19-15-11-18(22-3)17(21-2)10-14(15)16/h4-11H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290839 (4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...) Show SMILES COc1cc2nccc(Oc3cccc(Br)c3)c2cc1OC Show InChI InChI=1S/C17H14BrNO3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290843 (4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline | CHEM...) Show SMILES CCc1cccc(Oc2ccnc3cc(OC)c(OC)cc23)c1 Show InChI InChI=1S/C19H19NO3/c1-4-13-6-5-7-14(10-13)23-17-8-9-20-16-12-19(22-3)18(21-2)11-15(16)17/h5-12H,4H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290844 (6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline | CHEM...) Show SMILES COc1cc2nccc(Oc3cccc(c3)[N+]([O-])=O)c2cc1OC Show InChI InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-7-6-15(13)24-12-5-3-4-11(8-12)19(20)21/h3-10H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM3032 (CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...) Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC Show InChI InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290845 (6,7-Dimethoxy-4-m-tolyloxy-quinoline | CHEMBL98839) Show SMILES COc1cc2nccc(Oc3cccc(C)c3)c2cc1OC Show InChI InChI=1S/C18H17NO3/c1-12-5-4-6-13(9-12)22-16-7-8-19-15-11-18(21-3)17(20-2)10-14(15)16/h4-11H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290846 (3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine | C...) Show SMILES COc1cc2nccc(Oc3cccc(N)c3)c2cc1OC Show InChI InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290847 (6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline | CH...) Show SMILES COc1cccc(Oc2ccnc3cc(OC)c(OC)cc23)c1 Show InChI InChI=1S/C18H17NO4/c1-20-12-5-4-6-13(9-12)23-16-7-8-19-15-11-18(22-3)17(21-2)10-14(15)16/h4-11H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290834 (4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...) Show SMILES COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C19H19NO5/c1-21-16-6-5-12(9-17(16)22-2)25-15-7-8-20-14-11-19(24-4)18(23-3)10-13(14)15/h5-11H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290848 (6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline | CH...) Show SMILES COc1ccccc1Oc1ccnc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C18H17NO4/c1-20-15-6-4-5-7-16(15)23-14-8-9-19-13-11-18(22-3)17(21-2)10-12(13)14/h4-11H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290849 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...) Show SMILES COc1ccc(Nc2ccnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C19H20N2O4/c1-22-16-6-5-12(9-17(16)23-2)21-14-7-8-20-15-11-19(25-4)18(24-3)10-13(14)15/h5-11H,1-4H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290850 (3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol | CHEMBL...) Show SMILES COc1cc2nccc(Oc3cccc(O)c3)c2cc1OC Show InChI InChI=1S/C17H15NO4/c1-20-16-9-13-14(10-17(16)21-2)18-7-6-15(13)22-12-5-3-4-11(19)8-12/h3-10,19H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290835 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C18H19N3O4/c1-22-14-6-5-11(7-15(14)23-2)21-18-12-8-16(24-3)17(25-4)9-13(12)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290851 (4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline | CHE...) Show SMILES CCOc1cccc(Oc2ccnc3cc(OC)c(OC)cc23)c1 Show InChI InChI=1S/C19H19NO4/c1-4-23-13-6-5-7-14(10-13)24-17-8-9-20-16-12-19(22-3)18(21-2)11-15(16)17/h5-12H,4H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290852 (4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...) Show SMILES COc1cc(OC)cc(Oc2ccnc3cc(OC)c(OC)cc23)c1 Show InChI InChI=1S/C19H19NO5/c1-21-12-7-13(22-2)9-14(8-12)25-17-5-6-20-16-11-19(24-4)18(23-3)10-15(16)17/h5-11H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290853 (6,7-Dimethoxy-4-phenoxy-quinoline | CHEMBL327534) Show SMILES COc1cc2nccc(Oc3ccccc3)c2cc1OC Show InChI InChI=1S/C17H15NO3/c1-19-16-10-13-14(11-17(16)20-2)18-9-8-15(13)21-12-6-4-3-5-7-12/h3-11H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290854 (4-(2,6-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...) Show SMILES COc1cc2nccc(Oc3c(OC)cccc3OC)c2cc1OC Show InChI InChI=1S/C19H19NO5/c1-21-15-6-5-7-16(22-2)19(15)25-14-8-9-20-13-11-18(24-4)17(23-3)10-12(13)14/h5-11H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290838 (4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...) Show SMILES COc1cc2ncnc(Oc3cccc(Br)c3)c2cc1OC Show InChI InChI=1S/C16H13BrN2O3/c1-20-14-7-12-13(8-15(14)21-2)18-9-19-16(12)22-11-5-3-4-10(17)6-11/h3-9H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191945 (CHEMBL3904768) Show SMILES Cn1nccc1-c1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1F)C(=O)NCc1ccc(F)c(F)c1 Show InChI InChI=1S/C26H19F3N6O2/c1-34-22(6-8-32-34)16-7-9-35-23(14-30-24(35)12-16)26(37)33-21-11-17(3-5-19(21)28)25(36)31-13-15-2-4-18(27)20(29)10-15/h2-12,14H,13H2,1H3,(H,31,36)(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191946 (CHEMBL3950278) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2cccnc2)c1 Show InChI InChI=1S/C32H30FN7O2/c1-38-13-15-39(16-14-38)28-7-3-2-5-25(28)20-36-31(41)23-8-9-26(33)27(17-23)37-32(42)29-21-35-30-18-22(10-12-40(29)30)24-6-4-11-34-19-24/h2-12,17-19,21H,13-16,20H2,1H3,(H,36,41)(H,37,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191973 (CHEMBL3940697) Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1F)C(=O)NCCN1CCCC1(C)C Show InChI InChI=1S/C27H30FN7O2/c1-27(2)8-4-10-34(27)12-9-29-25(36)19-5-6-21(28)22(13-19)32-26(37)23-16-30-24-14-18(7-11-35(23)24)20-15-31-33(3)17-20/h5-7,11,13-17H,4,8-10,12H2,1-3H3,(H,29,36)(H,32,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191975 (CHEMBL3975580) Show SMILES Cn1nccc1-c1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1F)C(=O)NCC1CCC(C)(C)O1 Show InChI InChI=1S/C26H27FN6O3/c1-26(2)9-6-18(36-26)14-29-24(34)17-4-5-19(27)20(12-17)31-25(35)22-15-28-23-13-16(8-11-33(22)23)21-7-10-30-32(21)3/h4-5,7-8,10-13,15,18H,6,9,14H2,1-3H3,(H,29,34)(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191976 (CHEMBL3967097) Show SMILES CN(CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2ccnn2C)c1)C(C)(C)C Show InChI InChI=1S/C26H30FN7O2/c1-26(2,3)32(4)13-11-28-24(35)18-6-7-19(27)20(14-18)31-25(36)22-16-29-23-15-17(9-12-34(22)23)21-8-10-30-33(21)5/h6-10,12,14-16H,11,13H2,1-5H3,(H,28,35)(H,31,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191979 (CHEMBL3906976) Show SMILES Cc1ccc(cc1NC(=O)c1cnn2ccccc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H20N4O2/c1-16-10-11-18(22(28)24-14-17-7-3-2-4-8-17)13-20(16)26-23(29)19-15-25-27-12-6-5-9-21(19)27/h2-13,15H,14H2,1H3,(H,24,28)(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191980 (CHEMBL3985689) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1cnc(C)c(NC(=O)c2cnn3cc(ccc23)-c2ccnn2C)c1 Show InChI InChI=1S/C31H33N9O2/c1-21-26(36-31(42)25-19-35-40-20-23(8-9-29(25)40)27-10-11-34-38(27)3)16-24(18-32-21)30(41)33-17-22-6-4-5-7-28(22)39-14-12-37(2)13-15-39/h4-11,16,18-20H,12-15,17H2,1-3H3,(H,33,41)(H,36,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191972 (CHEMBL3895824) Show SMILES C[C@H]1CCC[C@@H](C)N1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2ccnn2C)c1 |r| Show InChI InChI=1S/C28H32FN7O2/c1-18-5-4-6-19(2)35(18)14-12-30-27(37)21-7-8-22(29)23(15-21)33-28(38)25-17-31-26-16-20(10-13-36(25)26)24-9-11-32-34(24)3/h7-11,13,15-19H,4-6,12,14H2,1-3H3,(H,30,37)(H,33,38)/t18-,19+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191974 (CHEMBL3913766) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2cnn(C)c2)c1 Show InChI InChI=1S/C31H31FN8O2/c1-37-11-13-39(14-12-37)27-6-4-3-5-23(27)17-34-30(41)22-7-8-25(32)26(15-22)36-31(42)28-19-33-29-16-21(9-10-40(28)29)24-18-35-38(2)20-24/h3-10,15-16,18-20H,11-14,17H2,1-2H3,(H,34,41)(H,36,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191981 (CHEMBL3979322) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2ccnn2C)c1 Show InChI InChI=1S/C31H31FN8O2/c1-37-13-15-39(16-14-37)27-6-4-3-5-23(27)19-34-30(41)22-7-8-24(32)25(17-22)36-31(42)28-20-33-29-18-21(10-12-40(28)29)26-9-11-35-38(26)2/h3-12,17-18,20H,13-16,19H2,1-2H3,(H,34,41)(H,36,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50192006 (CHEMBL3955987) Show SMILES Cn1nccc1-c1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1F)C(=O)NCCN1CCCC1(C)C Show InChI InChI=1S/C27H30FN7O2/c1-27(2)9-4-12-34(27)14-11-29-25(36)19-5-6-20(28)21(15-19)32-26(37)23-17-30-24-16-18(8-13-35(23)24)22-7-10-31-33(22)3/h5-8,10,13,15-17H,4,9,11-12,14H2,1-3H3,(H,29,36)(H,32,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50192005 (CHEMBL3947262) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnn3cc(ccc23)-c2ccnn2C)c1 Show InChI InChI=1S/C31H31FN8O2/c1-37-13-15-39(16-14-37)28-6-4-3-5-22(28)18-33-30(41)21-7-9-25(32)26(17-21)36-31(42)24-19-35-40-20-23(8-10-29(24)40)27-11-12-34-38(27)2/h3-12,17,19-20H,13-16,18H2,1-2H3,(H,33,41)(H,36,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50192007 (CHEMBL3902237) Show SMILES CCN(CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2ccnn2C)c1)C(C)(C)C Show InChI InChI=1S/C27H32FN7O2/c1-6-34(27(2,3)4)14-12-29-25(36)19-7-8-20(28)21(15-19)32-26(37)23-17-30-24-16-18(10-13-35(23)24)22-9-11-31-33(22)5/h7-11,13,15-17H,6,12,14H2,1-5H3,(H,29,36)(H,32,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191977 (CHEMBL3983564) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2cc[nH]n2)c1 Show InChI InChI=1S/C30H29FN8O2/c1-37-12-14-38(15-13-37)26-5-3-2-4-22(26)18-33-29(40)21-6-7-23(31)25(16-21)35-30(41)27-19-32-28-17-20(9-11-39(27)28)24-8-10-34-36-24/h2-11,16-17,19H,12-15,18H2,1H3,(H,33,40)(H,34,36)(H,35,41)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50192008 (CHEMBL3971140) Show SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3ccccn23)c1 Show InChI InChI=1S/C27H27FN6O2/c1-32-12-14-33(15-13-32)23-7-3-2-6-20(23)17-30-26(35)19-9-10-21(28)22(16-19)31-27(36)24-18-29-25-8-4-5-11-34(24)25/h2-11,16,18H,12-15,17H2,1H3,(H,30,35)(H,31,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50191978 (CHEMBL3915941) Show SMILES Cc1ncc(cc1NC(=O)c1cnn2cc(ccc12)-c1cnn(C)c1)C(=O)NCCN1CCCC1(C)C Show InChI InChI=1S/C27H32N8O2/c1-18-23(12-20(13-29-18)25(36)28-9-11-34-10-5-8-27(34,2)3)32-26(37)22-15-31-35-17-19(6-7-24(22)35)21-14-30-33(4)16-21/h6-7,12-17H,5,8-11H2,1-4H3,(H,28,36)(H,32,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research (NIBR) Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...				J Med Chem 59: 7901-14 (2016) Article DOI: 10.1021/acs.jmedchem.6b00703 BindingDB Entry DOI: 10.7270/Q25X2BW1
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Rattus norvegicus)	BDBM50290836 ((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...) Show SMILES COc1cc2nccc(Nc3cccc(Br)c3)c2cc1OC Show InChI InChI=1S/C17H15BrN2O2/c1-21-16-9-13-14(20-12-5-3-4-11(18)8-12)6-7-19-15(13)10-17(16)22-2/h3-10H,1-2H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.				Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R
					More data for this Ligand-Target Pair