Found 268 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor 2' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Somatostatin receptor type 2
(RAT) | BDBM50423340
(CHEMBL250304)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(F)c(F)c3)Cc12 Show InChI InChI=1S/C26H31F2N3O2/c1-29-16-19(12-18-13-21-17(14-24(18)29)4-3-5-25(21)33-2)26(32)31-10-8-30(9-11-31)20-6-7-22(27)23(28)15-20/h3-7,15,18-19,24H,8-14,16H2,1-2H3/t18-,19-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.741 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423308
(CHEMBL251753)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C31H34N6O4S2/c1-20-6-8-24(9-7-20)43(39,40)41-28-5-3-4-21-18-27-22(17-25(21)28)16-23(19-35(27)2)31(38)37-14-12-36(13-15-37)29-11-10-26-30(32-29)34-42-33-26/h3-11,22-23,27H,12-19H2,1-2H3/t22-,23-,27-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423466
(CHEMBL539415)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28BrClN4O/c1-30-15-16(26(33)32-11-9-31(10-12-32)18-7-5-17(28)6-8-18)13-20-19-3-2-4-22-24(19)21(14-23(20)30)25(27)29-22/h2-8,16,20,23,29H,9-15H2,1H3/t16-,20-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423333
(CHEMBL251111)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCC(CC3)n3c4ccccc4[nH]c3=O)Cc12 Show InChI InChI=1S/C28H34N4O3/c1-30-17-20(14-19-15-22-18(16-25(19)30)6-5-9-26(22)35-2)27(33)31-12-10-21(11-13-31)32-24-8-4-3-7-23(24)29-28(32)34/h3-9,19-21,25H,10-17H2,1-2H3,(H,29,34)/t19-,20-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423331
(CHEMBL250724)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4ccccc4n3)Cc12 Show InChI InChI=1S/C29H34N4O2/c1-31-19-23(16-22-17-24-21(18-26(22)31)7-5-9-27(24)35-2)29(34)33-14-12-32(13-15-33)28-11-10-20-6-3-4-8-25(20)30-28/h3-11,22-23,26H,12-19H2,1-2H3/t22-,23-,26-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423473
(CHEMBL401130)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H29ClN4O/c1-29-16-18(13-22-21-3-2-4-23-25(21)17(15-28-23)14-24(22)29)26(32)31-11-9-30(10-12-31)20-7-5-19(27)6-8-20/h2-8,15,18,22,24,28H,9-14,16H2,1H3/t18-,22-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423341
(CHEMBL250914)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCC(=CC3)c3ccccn3)Cc12 |c:21| Show InChI InChI=1S/C26H31N3O2/c1-28-17-21(14-20-15-22-19(16-24(20)28)6-5-8-25(22)31-2)26(30)29-12-9-18(10-13-29)23-7-3-4-11-27-23/h3-9,11,20-21,24H,10,12-17H2,1-2H3/t20-,21-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423357
(CHEMBL251110)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCC(=CC3)c3ncccn3)Cc12 |c:21| Show InChI InChI=1S/C25H30N4O2/c1-28-16-20(13-19-14-21-18(15-22(19)28)5-3-6-23(21)31-2)25(30)29-11-7-17(8-12-29)24-26-9-4-10-27-24/h3-7,9-10,19-20,22H,8,11-16H2,1-2H3/t19-,20-,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423363
(CHEMBL250912)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCC(=CC3)c3ccc(Cl)cc3)Cc12 |c:21| Show InChI InChI=1S/C27H31ClN2O2/c1-29-17-22(14-21-15-24-20(16-25(21)29)4-3-5-26(24)32-2)27(31)30-12-10-19(11-13-30)18-6-8-23(28)9-7-18/h3-10,21-22,25H,11-17H2,1-2H3/t21-,22-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423313
(CHEMBL249111)Show SMILES COc1ccc(C(C)=O)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12 Show InChI InChI=1S/C27H32N6O3S/c1-16(34)19-4-6-24(36-3)21-13-17-12-18(15-31(2)23(17)14-20(19)21)27(35)33-10-8-32(9-11-33)25-7-5-22-26(28-25)30-37-29-22/h4-7,17-18,23H,8-15H2,1-3H3/t17-,18-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.88E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423476
(CHEMBL251836)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C25H27N7OS/c1-30-14-16(11-18-17-3-2-4-19-23(17)15(13-26-19)12-21(18)30)25(33)32-9-7-31(8-10-32)22-6-5-20-24(27-22)29-34-28-20/h2-6,13,16,18,21,26H,7-12,14H2,1H3/t16-,18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.02E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423486
(CHEMBL252029)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H29N5O3/c1-28-16-18(13-22-21-3-2-4-23-25(21)17(15-27-23)14-24(22)28)26(32)30-11-9-29(10-12-30)19-5-7-20(8-6-19)31(33)34/h2-8,15,18,22,24,27H,9-14,16H2,1H3/t18-,22-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423330
(CHEMBL250922)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nonc4c3)Cc12 Show InChI InChI=1S/C26H31N5O3/c1-29-16-19(12-18-13-21-17(14-24(18)29)4-3-5-25(21)33-2)26(32)31-10-8-30(9-11-31)20-6-7-22-23(15-20)28-34-27-22/h3-7,15,18-19,24H,8-14,16H2,1-2H3/t18-,19-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423309
(CHEMBL399843)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)C(F)(F)F)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H29F3N4O6S/c1-30-16-19(25(34)32-11-9-31(10-12-32)20-5-7-21(8-6-20)33(35)36)13-18-14-22-17(15-23(18)30)3-2-4-24(22)39-40(37,38)26(27,28)29/h2-8,18-19,23H,9-16H2,1H3/t18-,19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.55E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423335
(CHEMBL250921)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4nonc34)Cc12 Show InChI InChI=1S/C26H31N5O3/c1-29-16-19(13-18-14-20-17(15-23(18)29)5-3-8-24(20)33-2)26(32)31-11-9-30(10-12-31)22-7-4-6-21-25(22)28-34-27-21/h3-8,18-19,23H,9-16H2,1-2H3/t18-,19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423317
(CHEMBL440236)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(C)(=O)=O)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H32N4O6S/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)36-37(2,34)35)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423475
(CHEMBL252032)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C25H26ClN7OS/c1-31-13-14(11-16-15-3-2-4-18-22(15)17(12-20(16)31)23(26)27-18)25(34)33-9-7-32(8-10-33)21-6-5-19-24(28-21)30-35-29-19/h2-6,14,16,20,27H,7-13H2,1H3/t14-,16-,20-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.89E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423314
(CHEMBL251754)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)C(F)(F)F)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C25H27F3N6O4S2/c1-32-14-17(24(35)34-9-7-33(8-10-34)22-6-5-19-23(29-22)31-39-30-19)11-16-12-18-15(13-20(16)32)3-2-4-21(18)38-40(36,37)25(26,27)28/h2-6,16-17,20H,7-14H2,1H3/t16-,17-,20-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.89E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423338
(CHEMBL400099)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4c3)Cc12 Show InChI InChI=1S/C26H31N5O2S/c1-29-16-19(12-18-13-21-17(14-24(18)29)4-3-5-25(21)33-2)26(32)31-10-8-30(9-11-31)20-6-7-22-23(15-20)28-34-27-22/h3-7,15,18-19,24H,8-14,16H2,1-2H3/t18-,19-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.27E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423351
(CHEMBL250305)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3C#N)[N+]([O-])=O)Cc12 Show InChI InChI=1S/C27H31N5O4/c1-29-17-21(12-19-14-23-18(15-25(19)29)4-3-5-26(23)36-2)27(33)31-10-8-30(9-11-31)24-7-6-22(32(34)35)13-20(24)16-28/h3-7,13,19,21,25H,8-12,14-15,17H2,1-2H3/t19-,21-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423478
(CHEMBL252033)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C25H26BrN7OS/c1-31-13-14(11-16-15-3-2-4-18-22(15)17(12-20(16)31)23(26)27-18)25(34)33-9-7-32(8-10-33)21-6-5-19-24(28-21)30-35-29-19/h2-6,14,16,20,27H,7-13H2,1H3/t14-,16-,20-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423307
(CHEMBL399464)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OCc1ccccc1)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C31H34N6O2S/c1-35-19-24(31(38)37-14-12-36(13-15-37)29-11-10-26-30(32-29)34-40-33-26)16-23-17-25-22(18-27(23)35)8-5-9-28(25)39-20-21-6-3-2-4-7-21/h2-11,23-24,27H,12-20H2,1H3/t23-,24-,27-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423345
(CHEMBL428583)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3[N+]([O-])=O)C(F)(F)F)Cc12 Show InChI InChI=1S/C27H31F3N4O4/c1-31-16-19(12-18-13-21-17(14-23(18)31)4-3-5-25(21)38-2)26(35)33-10-8-32(9-11-33)22-7-6-20(27(28,29)30)15-24(22)34(36)37/h3-7,15,18-19,23H,8-14,16H2,1-2H3/t18-,19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423369
(CHEMBL250703)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)C(F)(F)F)Cc12 Show InChI InChI=1S/C27H32F3N3O2/c1-31-17-20(14-19-15-23-18(16-24(19)31)4-3-5-25(23)35-2)26(34)33-12-10-32(11-13-33)22-8-6-21(7-9-22)27(28,29)30/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423483
(CHEMBL398526)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1 Show InChI InChI=1S/C26H27ClN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423299
(CHEMBL401290)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(C)(=O)=O)C(=O)N1CCN(CC1)c1ccc2nsnc2n1 Show InChI InChI=1S/C25H30N6O4S2/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)35-37(2,33)34)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-36-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423344
(CHEMBL250522)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4ccc(cc34)C#N)Cc12 Show InChI InChI=1S/C31H34N4O2/c1-33-20-25(16-24-17-27-23(18-29(24)33)6-4-8-30(27)37-2)31(36)35-13-11-34(12-14-35)28-7-3-5-22-10-9-21(19-32)15-26(22)28/h3-10,15,24-25,29H,11-14,16-18,20H2,1-2H3/t24-,25-,29-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423337
(CHEMBL400137)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3S(C)(=O)=O)[N+]([O-])=O)Cc12 Show InChI InChI=1S/C27H34N4O6S/c1-28-17-20(13-19-14-22-18(15-24(19)28)5-4-6-25(22)37-2)27(32)30-11-9-29(10-12-30)23-8-7-21(31(33)34)16-26(23)38(3,35)36/h4-8,16,19-20,24H,9-15,17H2,1-3H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423366
(CHEMBL250723)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cc(C)nc4ccccc34)Cc12 Show InChI InChI=1S/C30H36N4O2/c1-20-15-28(24-8-4-5-9-26(24)31-20)33-11-13-34(14-12-33)30(35)23-16-22-17-25-21(7-6-10-29(25)36-3)18-27(22)32(2)19-23/h4-10,15,22-23,27H,11-14,16-19H2,1-3H3/t22-,23-,27-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423346
(CHEMBL440962)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cc4ccccc4cn3)Cc12 Show InChI InChI=1S/C29H34N4O2/c1-31-19-24(14-23-15-25-21(16-26(23)31)8-5-9-27(25)35-2)29(34)33-12-10-32(11-13-33)28-17-20-6-3-4-7-22(20)18-30-28/h3-9,17-18,23-24,26H,10-16,19H2,1-2H3/t23-,24-,26-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423370
(CHEMBL250521)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4ccccc34)Cc12 Show InChI InChI=1S/C30H35N3O2/c1-31-20-24(17-23-18-26-22(19-28(23)31)9-6-12-29(26)35-2)30(34)33-15-13-32(14-16-33)27-11-5-8-21-7-3-4-10-25(21)27/h3-12,23-24,28H,13-20H2,1-2H3/t23-,24-,28-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423459
(CHEMBL253653)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(I)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C25H28IN5O/c1-29-15-16(25(32)31-11-9-30(10-12-31)22-7-2-3-8-27-22)13-18-17-5-4-6-20-23(17)19(14-21(18)29)24(26)28-20/h2-8,16,18,21,28H,9-15H2,1H3/t16-,18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.62E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423302
(CHEMBL248715)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12 Show InChI InChI=1S/C25H30N6O2S/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)33-2)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-34-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423302
(CHEMBL248715)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12 Show InChI InChI=1S/C25H30N6O2S/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)33-2)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-34-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423301
(CHEMBL251542)Show SMILES CC(C)Oc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12 Show InChI InChI=1S/C28H36N4O4/c1-19(2)36-27-6-4-5-20-17-26-21(16-25(20)27)15-22(18-29(26)3)28(33)31-13-11-30(12-14-31)23-7-9-24(10-8-23)32(34)35/h4-10,19,21-22,26H,11-18H2,1-3H3/t21-,22-,26-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423484
(CHEMBL401131)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28Cl2N4O/c1-30-15-16(26(33)32-11-9-31(10-12-32)18-7-5-17(27)6-8-18)13-20-19-3-2-4-22-24(19)21(14-23(20)30)25(28)29-22/h2-8,16,20,23,29H,9-15H2,1H3/t16-,20-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.89E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423336
(CHEMBL251300)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCc4c(C3)[nH]c3ccccc43)Cc12 Show InChI InChI=1S/C27H31N3O2/c1-29-15-19(12-18-13-22-17(14-25(18)29)6-5-9-26(22)32-2)27(31)30-11-10-21-20-7-3-4-8-23(20)28-24(21)16-30/h3-9,18-19,25,28H,10-16H2,1-2H3/t18-,19-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 6.17E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423303
(CHEMBL248907)Show SMILES COc1ccc(Br)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12 Show InChI InChI=1S/C25H29BrN6O2S/c1-30-14-16(11-15-12-18-17(13-21(15)30)19(26)3-5-22(18)34-2)25(33)32-9-7-31(8-10-32)23-6-4-20-24(27-23)29-35-28-20/h3-6,15-16,21H,7-14H2,1-2H3/t15-,16-,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423462
(CHEMBL251835)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1 Show InChI InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.46E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423353
(CHEMBL251116)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc(OCc4ccccc4)n3)Cc12 Show InChI InChI=1S/C32H38N4O3/c1-34-21-26(18-25-19-27-24(20-28(25)34)10-6-11-29(27)38-2)32(37)36-16-14-35(15-17-36)30-12-7-13-31(33-30)39-22-23-8-4-3-5-9-23/h3-13,25-26,28H,14-22H2,1-2H3/t25-,26-,28-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.61E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423352
(CHEMBL250498)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc(c3)[N+]([O-])=O)Cc12 Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(13-19-14-23-18(15-24(19)27)5-3-8-25(23)34-2)26(31)29-11-9-28(10-12-29)21-6-4-7-22(16-21)30(32)33/h3-8,16,19-20,24H,9-15,17H2,1-2H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423339
(CHEMBL250920)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cc4nccnc4cn3)Cc12 Show InChI InChI=1S/C27H32N6O2/c1-31-17-20(12-19-13-21-18(14-24(19)31)4-3-5-25(21)35-2)27(34)33-10-8-32(9-11-33)26-15-22-23(16-30-26)29-7-6-28-22/h3-7,15-16,19-20,24H,8-14,17H2,1-2H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.08E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423318
(CHEMBL251752)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3C(C)=O)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C27H32N4O4/c1-18(32)24-5-3-4-19-16-26-20(15-25(19)24)14-21(17-28(26)2)27(33)30-12-10-29(11-13-30)22-6-8-23(9-7-22)31(34)35/h3-9,20-21,26H,10-17H2,1-2H3/t20-,21-,26-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423300
(CHEMBL401091)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3C#N)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H29N5O3/c1-28-17-21(13-20-14-24-18(15-25(20)28)3-2-4-19(24)16-27)26(32)30-11-9-29(10-12-30)22-5-7-23(8-6-22)31(33)34/h2-8,20-21,25H,9-15,17H2,1H3/t20-,21-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423479
(CHEMBL252229)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H28BrN5O3/c1-29-15-16(13-20-19-3-2-4-22-24(19)21(14-23(20)29)25(27)28-22)26(33)31-11-9-30(10-12-31)17-5-7-18(8-6-17)32(34)35/h2-8,16,20,23,28H,9-15H2,1H3/t16-,20-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423364
(CHEMBL249930)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccccc3C#N)Cc12 Show InChI InChI=1S/C27H32N4O2/c1-29-18-22(14-21-15-23-19(16-25(21)29)7-5-9-26(23)33-2)27(32)31-12-10-30(11-13-31)24-8-4-3-6-20(24)17-28/h3-9,21-22,25H,10-16,18H2,1-2H3/t21-,22-,25-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.41E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3988-91 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423487
(CHEMBL401108)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c([nH]c3cccc2c13)S(C)(=O)=O)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C26H31N5O3S/c1-29-16-17(26(32)31-12-10-30(11-13-31)23-8-3-4-9-27-23)14-19-18-6-5-7-21-24(18)20(15-22(19)29)25(28-21)35(2,33)34/h3-9,17,19,22,28H,10-16H2,1-2H3/t17-,19-,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423471
(CHEMBL254288)Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C Show InChI InChI=1S/C26H31N5O2/c1-28-16-18(13-20-19-5-3-6-21-25(19)17(15-27-21)14-22(20)28)26(33)31-11-9-30(10-12-31)23-7-4-8-24(32)29(23)2/h3-8,15,18,20,22,27H,9-14,16H2,1-2H3/t18-,20-,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I][Tyr3]octreotide from sst2 receptor in rat cortex |
Bioorg Med Chem Lett 18: 979-82 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423310
(CHEMBL251543)Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(O)cccc3C[C@@H]12)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C25H30N4O4/c1-26-16-19(13-18-14-22-17(15-23(18)26)3-2-4-24(22)30)25(31)28-11-9-27(10-12-28)20-5-7-21(8-6-20)29(32)33/h2-8,18-19,23,30H,9-16H2,1H3/t18-,19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50423297
(CHEMBL251541 | Obelin)Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12 Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]SRIF14 from sst2 receptor in rat brain cortex membrane |
Bioorg Med Chem Lett 17: 3983-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675 |
More data for this
Ligand-Target Pair | |
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