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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Src homology 2 domain (SH2-wt)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase transforming protein Src [144-247]


(Rous sarcoma virus (Virus))
BDBM195583
PNG
(Phosphotyrosine (pTyr))
Show SMILES [NH3+][C@@H](Cc1ccc(OP([O-])([O-])=O)cc1)C([O-])=O |r|
Show InChI InChI=1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/p-2/t8-/m0/s1
PDB

UniProtKB/SwissProt

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MCE
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 61n/an/an/a7.35n/a



University of Nebraska-Lincoln



Assay Description
Three fluorescein-labeled peptide probes, FITC-sulfopeptide, FITC-phosphopeptide, and FITC-tyrosinepeptide (FITC, fluorescein isothiocyanate), were u...


ACS Chem Biol 11: 2551-7 (2016)


Article DOI: 10.1021/acschembio.6b00555
BindingDB Entry DOI: 10.7270/Q2154FT9
More data for this
Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src [144-247]


(Rous sarcoma virus (Virus))
BDBM195582
PNG
(Sulfotyrosine (sTyr))
Show SMILES [NH3+][C@@H](Cc1ccc(OS([O-])(=O)=O)cc1)C([O-])=O |r|
Show InChI InChI=1S/C9H11NO6S/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H,13,14,15)/p-1/t8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 9.62E+3n/an/an/a7.35n/a



University of Nebraska-Lincoln



Assay Description
Three fluorescein-labeled peptide probes, FITC-sulfopeptide, FITC-phosphopeptide, and FITC-tyrosinepeptide (FITC, fluorescein isothiocyanate), were u...


ACS Chem Biol 11: 2551-7 (2016)


Article DOI: 10.1021/acschembio.6b00555
BindingDB Entry DOI: 10.7270/Q2154FT9
More data for this
Ligand-Target Pair