Compile Data Set for Download or QSAR

Found 151 hits Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50025834 (CHEMBL3330880) Show SMILES COc1cc(NC(C)=O)c(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 Show InChI InChI=1S/C25H31ClN4O6S/c1-16(31)28-22-15-23(36-2)20(14-21(22)26)24(32)27-13-12-17-8-10-19(11-9-17)37(34,35)30-25(33)29-18-6-4-3-5-7-18/h8-11,14-15,18H,3-7,12-13H2,1-2H3,(H,27,32)(H,28,31)(H2,29,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Binding affinity to SUR1 (unknown origin)				Eur J Med Chem 86: 491-501 (2014) Article DOI: 10.1016/j.ejmech.2014.09.007 BindingDB Entry DOI: 10.7270/Q2319XGR
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50025847 (CHEMBL3330879) Show SMILES COc1cc(NC(=O)CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 |r| Show InChI InChI=1S/C31H41ClN4O12S/c1-46-23-14-22(35-25(38)16-47-30-28(41)27(40)26(39)24(15-37)48-30)21(32)13-20(23)29(42)33-12-11-17-7-9-19(10-8-17)49(44,45)36-31(43)34-18-5-3-2-4-6-18/h7-10,13-14,18,24,26-28,30,37,39-41H,2-6,11-12,15-16H2,1H3,(H,33,42)(H,35,38)(H2,34,36,43)/t24-,26-,27+,28-,30+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Binding affinity to SUR1 (unknown origin)				Eur J Med Chem 86: 491-501 (2014) Article DOI: 10.1016/j.ejmech.2014.09.007 BindingDB Entry DOI: 10.7270/Q2319XGR
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50153520 ((S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)p...) Show SMILES CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O |r| Show InChI InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)				Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF
					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50153521 (2-Methoxy-4-{[(S)-3-methyl-1-(2-piperidin-1-yl-phe...) Show SMILES COc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O Show InChI InChI=1S/C26H34N2O4/c1-18(2)15-22(20-9-5-6-10-23(20)28-13-7-4-8-14-28)27-25(29)17-19-11-12-21(26(30)31)24(16-19)32-3/h5-6,9-12,16,18,22H,4,7-8,13-15,17H2,1-3H3,(H,27,29)(H,30,31)/t22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)				Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50153522 (2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...) Show SMILES CC(C)C[C@H](NC(=O)Cc1ccc(C(O)=O)c(OCCF)c1)c1ccccc1N1CCCCC1 Show InChI InChI=1S/C27H35FN2O4/c1-19(2)16-23(21-8-4-5-9-24(21)30-13-6-3-7-14-30)29-26(31)18-20-10-11-22(27(32)33)25(17-20)34-15-12-28/h4-5,8-11,17,19,23H,3,6-7,12-16,18H2,1-2H3,(H,29,31)(H,32,33)/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)				Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 |r| Show InChI InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Homo sapiens (Human))	BDBM50153522 (2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...) Show SMILES CC(C)C[C@H](NC(=O)Cc1ccc(C(O)=O)c(OCCF)c1)c1ccccc1N1CCCCC1 Show InChI InChI=1S/C27H35FN2O4/c1-19(2)16-23(21-8-4-5-9-24(21)30-13-6-3-7-14-30)29-26(31)18-20-10-11-22(27(32)33)25(17-20)34-15-12-28/h4-5,8-11,17,19,23H,3,6-7,12-16,18H2,1-2H3,(H,29,31)(H,32,33)/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	281	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)				Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127761 (CHEMBL49390 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(OC(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F9NO3/c22-19(23,24)18(33,20(25,26)27)15-10-7-11-3-1-2-4-14(11)16(15)31-17(32)12-5-8-13(9-6-12)34-21(28,29)30/h1-10,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127762 (CHEMBL47170 | Cyclobutanecarboxylic acid [2-(2,2,2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c19-17(20,21)16(27,18(22,23)24)13-9-8-10-4-1-2-7-12(10)14(13)25-15(26)11-5-3-6-11/h1-2,4,7-9,11,27H,3,5-6H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127763 (4-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES Cc1ccc(cc1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO2/c1-12-6-8-14(9-7-12)18(29)28-17-15-5-3-2-4-13(15)10-11-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127764 (3-Methyl-but-2-enoic acid [2-(2,2,2-trifluoro-1-hy...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1c(ccc2ccccc12)C([#8])(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c1-10(2)9-14(26)25-15-12-6-4-3-5-11(12)7-8-13(15)16(27,17(19,20)21)18(22,23)24/h3-9,27H,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127765 (CHEMBL45645 | [2-(2,2,2-Trifluoro-1-hydroxy-1-trif...) Show SMILES CC(C)OC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO3/c1-9(2)27-14(25)24-13-11-6-4-3-5-10(11)7-8-12(13)15(26,16(18,19)20)17(21,22)23/h3-9,26H,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127766 (4-Fluoro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F7NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127768 (CHEMBL299167 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-t...) Show SMILES CC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H11F6NO2/c1-8(23)22-12-10-5-3-2-4-9(10)6-7-11(12)13(24,14(16,17)18)15(19,20)21/h2-7,24H,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127767 (CHEMBL301591 | Quinoxaline-2-carboxylic acid [2-(2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cnc2ccccc2n1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H13F6N3O2/c23-21(24,25)20(33,22(26,27)28)14-10-9-12-5-1-2-6-13(12)18(14)31-19(32)17-11-29-15-7-3-4-8-16(15)30-17/h1-11,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127769 (4-Iodo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoro...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(I)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F6INO2/c21-19(22,23)18(30,20(24,25)26)15-10-7-11-3-1-2-4-14(11)16(15)28-17(29)12-5-8-13(27)9-6-12/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	154	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127770 (1-(6-Chloro-hexyl)-3-[2-(2,2,2-trifluoro-1-hydroxy...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)NCCCCCCCl)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H21ClF6N2O2/c21-11-5-1-2-6-12-28-17(30)29-16-14-8-4-3-7-13(14)9-10-15(16)18(31,19(22,23)24)20(25,26)27/h3-4,7-10,31H,1-2,5-6,11-12H2,(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127772 (2-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccccc1Cl)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12ClF6NO2/c21-15-8-4-3-7-13(15)17(29)28-16-12-6-2-1-5-11(12)9-10-14(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127771 (4-Methyl-pentanoic acid [2-(2,2,2-trifluoro-1-hydr...) Show SMILES CC(C)CCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H19F6NO2/c1-11(2)7-10-15(27)26-16-13-6-4-3-5-12(13)8-9-14(16)17(28,18(20,21)22)19(23,24)25/h3-6,8-9,11,28H,7,10H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127773 (3,4-Dichloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tri...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Cl)c(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11Cl2F6NO2/c21-14-8-6-11(9-15(14)22)17(30)29-16-12-4-2-1-3-10(12)5-7-13(16)18(31,19(23,24)25)20(26,27)28/h1-9,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	194	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127774 (3-Nitro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(c1)[N+]([O-])=O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F6N2O4/c21-19(22,23)18(30,20(24,25)26)15-9-8-11-4-1-2-7-14(11)16(15)27-17(29)12-5-3-6-13(10-12)28(31)32/h1-10,30H,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127776 (1-(4-Chloro-phenyl)-3-[2-(2,2,2-trifluoro-1-hydrox...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)Nc1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H13ClF6N2O2/c21-12-6-8-13(9-7-12)28-17(30)29-16-14-4-2-1-3-11(14)5-10-15(16)18(31,19(22,23)24)20(25,26)27/h1-10,31H,(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	276	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127775 (CHEMBL298970 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-t...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(c1)C(F)(F)F)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F9NO2/c22-19(23,24)13-6-3-5-12(10-13)17(32)31-16-14-7-2-1-4-11(14)8-9-15(16)18(33,20(25,26)27)21(28,29)30/h1-10,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127778 (3,5-Dichloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tri...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cc(Cl)cc(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11Cl2F6NO2/c21-12-7-11(8-13(22)9-12)17(30)29-16-14-4-2-1-3-10(14)5-6-15(16)18(31,19(23,24)25)20(26,27)28/h1-9,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	306	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127777 (But-2-enoic acid [2-(2,2,2-trifluoro-1-hydroxy-1-t...) Show SMILES C\C=C\C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H13F6NO2/c1-2-5-13(25)24-14-11-7-4-3-6-10(11)8-9-12(14)15(26,16(18,19)20)17(21,22)23/h2-9,26H,1H3,(H,24,25)/b5-2+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127779 (2-Methyl-pentanoic acid [2-(2,2,2-trifluoro-1-hydr...) Show SMILES CCCC(C)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H19F6NO2/c1-3-6-11(2)16(27)26-15-13-8-5-4-7-12(13)9-10-14(15)17(28,18(20,21)22)19(23,24)25/h4-5,7-11,28H,3,6H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127780 (Benzo[b]thiophene-2-carboxylic acid [2-(2,2,2-trif...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cc2ccccc2s1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H13F6NO2S/c23-21(24,25)20(31,22(26,27)28)15-10-9-12-5-1-3-7-14(12)18(15)29-19(30)17-11-13-6-2-4-8-16(13)32-17/h1-11,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127781 (CHEMBL49701 | N-[5-Hydroxy-2-(2,2,2-trifluoro-1-hy...) Show SMILES CC(=O)Nc1c(ccc2c(O)cccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H11F6NO3/c1-7(23)22-12-9-3-2-4-11(24)8(9)5-6-10(12)13(25,14(16,17)18)15(19,20)21/h2-6,24-25H,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	137	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127783 (CHEMBL49076 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccnc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H12F6N2O2/c20-18(21,22)17(29,19(23,24)25)14-8-7-11-4-1-2-6-13(11)15(14)27-16(28)12-5-3-9-26-10-12/h1-10,29H,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127782 (2-Ethyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES CCC(CC)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H19F6NO2/c1-3-11(4-2)16(27)26-15-13-8-6-5-7-12(13)9-10-14(15)17(28,18(20,21)22)19(23,24)25/h5-11,28H,3-4H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127785 (4-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12BrF6NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127786 (CHEMBL49797 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES CCCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO2/c1-2-5-13(25)24-14-11-7-4-3-6-10(11)8-9-12(14)15(26,16(18,19)20)17(21,22)23/h3-4,6-9,26H,2,5H2,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127795 (4-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES COc1ccc(cc1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO3/c1-31-14-9-6-13(7-10-14)18(29)28-17-15-5-3-2-4-12(15)8-11-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127787 (2-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES COCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H13F6NO3/c1-26-8-12(24)23-13-10-5-3-2-4-9(10)6-7-11(13)14(25,15(17,18)19)16(20,21)22/h2-7,25H,8H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	213	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127796 (2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES CCC(C)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H17F6NO2/c1-3-10(2)15(26)25-14-12-7-5-4-6-11(12)8-9-13(14)16(27,17(19,20)21)18(22,23)24/h4-10,27H,3H2,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127790 (3-Phenyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)CCc1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H17F6NO2/c23-21(24,25)20(31,22(26,27)28)17-12-11-15-8-4-5-9-16(15)19(17)29-18(30)13-10-14-6-2-1-3-7-14/h1-9,11-12,31H,10,13H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127791 (4-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12ClF6NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127788 (3-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES Cc1cccc(c1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO2/c1-12-5-4-7-14(11-12)18(29)28-17-15-8-3-2-6-13(15)9-10-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127784 (CHEMBL48801 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(cc1)C(F)(F)F)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F9NO2/c22-19(23,24)13-8-5-12(6-9-13)17(32)31-16-14-4-2-1-3-11(14)7-10-15(16)18(33,20(25,26)27)21(28,29)30/h1-10,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127789 (CHEMBL49191 | Cyclopentanecarboxylic acid [2-(2,2,...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CCCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H17F6NO2/c20-18(21,22)17(28,19(23,24)25)14-10-9-11-5-3-4-8-13(11)15(14)26-16(27)12-6-1-2-7-12/h3-5,8-10,12,28H,1-2,6-7H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	495	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127792 (3-Fluoro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(F)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F7NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127794 (CHEMBL48848 | Furan-2-carboxylic acid [2-(2,2,2-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccco1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H11F6NO3/c19-17(20,21)16(27,18(22,23)24)12-8-7-10-4-1-2-5-11(10)14(12)25-15(26)13-6-3-9-28-13/h1-9,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127793 (CHEMBL48797 | Oxazole-5-carboxylic acid [2-(2,2,2-...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cnco1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F6N2O3/c18-16(19,20)15(27,17(21,22)23)11-6-5-9-3-1-2-4-10(9)13(11)25-14(26)12-7-24-8-28-12/h1-8,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127801 (CHEMBL50760 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES CCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H13F6NO2/c1-2-12(24)23-13-10-6-4-3-5-9(10)7-8-11(13)14(25,15(17,18)19)16(20,21)22/h3-8,25H,2H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127797 (3-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(Br)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12BrF6NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127798 (CHEMBL50374 | Thiophene-2-carboxylic acid [2-(2,2,...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccs1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H11F6NO2S/c19-17(20,21)16(27,18(22,23)24)12-8-7-10-4-1-2-5-11(10)14(12)25-15(26)13-6-3-9-28-13/h1-9,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127799 (CHEMBL51071 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H13F6NO2/c21-19(22,23)18(29,20(24,25)26)15-11-10-12-6-4-5-9-14(12)16(15)27-17(28)13-7-2-1-3-8-13/h1-11,29H,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127802 (3-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12ClF6NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127803 (CHEMBL50501 | N-[4-Bromo-2-(2,2,2-trifluoro-1-hydr...) Show SMILES CC(=O)Nc1c(cc(Br)c2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H10BrF6NO2/c1-7(24)23-12-9-5-3-2-4-8(9)11(16)6-10(12)13(25,14(17,18)19)15(20,21)22/h2-6,25H,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	5.31E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127800 (CHEMBL296840 | Cyclopropanecarboxylic acid [2-(2,2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H13F6NO2/c18-16(19,20)15(26,17(21,22)23)12-8-7-9-3-1-2-4-11(9)13(12)24-14(25)10-5-6-10/h1-4,7-8,10,26H,5-6H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	751	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair

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