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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'trans-Sialidase (TS D247A)'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Trans-sialidase [3-643,D247A]


(Trypanosoma cruzi)		BDBM217358
PNG
(α2,3'-sialyllactose | 3-SL)
Show SMILES CC(=O)NC1C(O)CC(OC2C(O)C(CO)OC(OC3C(CO)OC(O)C(O)C3O)C2O)(OC1[C@H](O)[C@H](O)CO)C(O)=O |r|
Show InChI InChI=1S/C23H39NO19/c1-6(28)24-11-7(29)2-23(22(37)38,42-18(11)12(31)8(30)3-25)43-19-13(32)9(4-26)40-21(16(19)35)41-17-10(5-27)39-20(36)15(34)14(17)33/h7-21,25-27,29-36H,2-5H2,1H3,(H,24,28)(H,37,38)/t7?,8-,9?,10?,11?,12-,13?,14?,15?,16?,17?,18?,19?,20?,21?,23?/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.07E+5n/an/an/an/a11



Universidade Federal do Rio de Janeiro



Assay Description
Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...

J Biol Chem 289: 423-36 (2014)


Article DOI: 10.1074/jbc.M112.399303
BindingDB Entry DOI: 10.7270/Q2VT1QZ8
More data for this
Ligand-Target Pair