Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Streptococcus pneumoniae (ATCC49619)) | BDBM18071 (5-chloro-3-({4-[(2,4-diaminopyrimidin-5-yl)methyl]...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | 9 | -46.7 | 90 | n/a | n/a | n/a | n/a | 7.0 | 30 | |
ARPIDA AG | Assay Description Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba... | Interscience Conference on Antimicrobial Agents in Chemotherapy 1-1 (2006) BindingDB Entry DOI: 10.7270/Q2959FTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Streptococcus pneumoniae (ATCC49619)) | BDBM18069 (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | 5.60E+3 | -30.5 | 4.20E+4 | n/a | n/a | n/a | n/a | 7.0 | 30 | |
ARPIDA AG | Assay Description Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba... | Interscience Conference on Antimicrobial Agents in Chemotherapy 1-1 (2006) BindingDB Entry DOI: 10.7270/Q2959FTP | |||||||||||
More data for this Ligand-Target Pair |