Compile Data Set for Download or QSAR

Found 65 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase VHX (VHX)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM84581 (Thioxothiazolidinone derivative, 1) Show SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(Cl)c2)cc(c1O)N(=O)=O Show InChI InChI=1S/C17H11ClN2O5S2/c1-25-13-6-9(5-12(15(13)21)20(23)24)7-14-16(22)19(17(26)27-14)11-4-2-3-10(18)8-11/h2-8,21H,1H3/b14-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	6.0	25
McGill University					Assay Description PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...				Chembiochem 8: 179-86 (2007) Article DOI: 10.1002/cbic.200600287 BindingDB Entry DOI: 10.7270/Q2T72FZ5
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM199180 (US9217012, 10) Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)COC1CC(C)CCC1C(C)C)C(N)=O Show InChI InChI=1S/C46H62F2N5O9P/c1-5-31-15-19-34(20-16-31)43(56)50-24-10-9-13-37(42(49)55)52-45(58)39(27-33-17-21-35(22-18-33)46(47,48)63(59,60)61)53-44(57)38(26-32-11-7-6-8-12-32)51-41(54)28-62-40-25-30(4)14-23-36(40)29(2)3/h6-8,11-12,15-22,29-30,36-40H,5,9-10,13-14,23-28H2,1-4H3,(H2,49,55)(H,50,56)(H,51,54)(H,52,58)(H,53,57)(H2,59,60,61)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	>-34.2	n/a	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM231167 (US9340574, 7) Show SMILES COc1cc(CC(=O)NCC(NC(=O)C(CCCNC(=O)c2cccc(I)c2)NC(=O)C(Cc2ccc(cc2)C(F)(F)P(O)(O)=O)NC(=O)c2ccc(C)c(Br)c2)C(N)=O)ccc1O Show InChI InChI=1S/C42H45BrF2IN6O11P/c1-23-8-12-27(21-30(23)43)39(57)51-32(17-24-9-13-28(14-10-24)42(44,45)64(60,61)62)41(59)50-31(7-4-16-48-38(56)26-5-3-6-29(46)20-26)40(58)52-33(37(47)55)22-49-36(54)19-25-11-15-34(53)35(18-25)63-2/h3,5-6,8-15,18,20-21,31-33,53H,4,7,16-17,19,22H2,1-2H3,(H2,47,55)(H,48,56)(H,49,54)(H,50,59)(H,51,57)(H,52,58)(H2,60,61,62)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.0	n/a
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...				US Patent US9340574 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H4J
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168876 (3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1cccc(c1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO3S2/c19-15-14(9-11-5-2-1-3-6-11)23-17(22)18(15)13-8-4-7-12(10-13)16(20)21/h1-10H,(H,20,21)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168874 (3-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...) Show SMILES OC(=O)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(F)cc2)C1=O Show InChI InChI=1S/C17H10FNO3S2/c18-12-6-4-10(5-7-12)8-14-15(20)19(17(23)24-14)13-3-1-2-11(9-13)16(21)22/h1-9H,(H,21,22)/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168875 (3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-t...) Show SMILES Cc1ccc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C18H13NO3S2/c1-11-5-7-12(8-6-11)9-15-16(20)19(18(23)24-15)14-4-2-3-13(10-14)17(21)22/h2-10H,1H3,(H,21,22)/b15-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168878 ((3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...) Show SMILES OC(=O)Cc1cccc(c1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C18H13NO3S2/c20-16(21)11-13-7-4-8-14(9-13)19-17(22)15(24-18(19)23)10-12-5-2-1-3-6-12/h1-10H,11H2,(H,20,21)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168879 (3-Phenyl-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES O=C1N(C(=S)S\C1=C/c1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H11NOS2/c18-15-14(11-12-7-3-1-4-8-12)20-16(19)17(15)13-9-5-2-6-10-13/h1-11H/b14-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168880 (4-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...) Show SMILES OC(=O)c1ccc(cc1)N1C(=S)O\C(=C/c2ccc(F)cc2)C1=O Show InChI InChI=1S/C17H10FNO4S/c18-12-5-1-10(2-6-12)9-14-15(20)19(17(24)23-14)13-7-3-11(4-8-13)16(21)22/h1-9H,(H,21,22)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168881 (4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO3S2/c19-15-14(10-11-4-2-1-3-5-11)23-17(22)18(15)13-8-6-12(7-9-13)16(20)21/h1-10H,(H,20,21)/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168884 (4-{4-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-3-meth...) Show SMILES CN1C(=S)N(C(=O)\C1=C\c1ccc(F)cc1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C18H13FN2O3S/c1-20-15(10-11-2-6-13(19)7-3-11)16(22)21(18(20)25)14-8-4-12(5-9-14)17(23)24/h2-10H,1H3,(H,23,24)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168877 (2-Hydroxy-5-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...) Show SMILES OC(=O)c1cc(ccc1O)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO4S2/c19-13-7-6-11(9-12(13)16(21)22)18-15(20)14(24-17(18)23)8-10-4-2-1-3-5-10/h1-9,19H,(H,21,22)/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168885 (3-{5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-4-oxo-2...) Show SMILES OC(=O)c1cccc(c1)-n1c([O-])c([CH+]c2ccc(cc2)[N+]([O-])=O)sc1=S Show InChI InChI=1S/C17H10N2O5S2/c20-15-14(8-10-4-6-12(7-5-10)19(23)24)26-17(25)18(15)13-3-1-2-11(9-13)16(21)22/h1-9H,(H-,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168887 (4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1ccc(CN2C(=S)S\C(=C/c3ccccc3)C2=O)cc1 Show InChI InChI=1S/C18H13NO3S2/c20-16-15(10-12-4-2-1-3-5-12)24-18(23)19(16)11-13-6-8-14(9-7-13)17(21)22/h1-10H,11H2,(H,21,22)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168876 (3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1cccc(c1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO3S2/c19-15-14(9-11-5-2-1-3-6-11)23-17(22)18(15)13-8-4-7-12(10-13)16(20)21/h1-10H,(H,20,21)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168873 (3-[4-Oxo-5-prop-(Z)-ylidene-2-thioxo-thiazolidin-3...) Show SMILES CC\C=C1/SC(=S)N(C1=O)c1cccc(c1)C(O)=O Show InChI InChI=1S/C13H11NO3S2/c1-2-4-10-11(15)14(13(18)19-10)9-6-3-5-8(7-9)12(16)17/h3-7H,2H2,1H3,(H,16,17)/b10-4-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168890 (2-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1ccccc1N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO3S2/c19-15-14(10-11-6-2-1-3-7-11)23-17(22)18(15)13-9-5-4-8-12(13)16(20)21/h1-10H,(H,20,21)/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168888 (5-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OC(=O)c1cc(cc(c1)C(O)=O)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C18H11NO5S2/c20-15-14(6-10-4-2-1-3-5-10)26-18(25)19(15)13-8-11(16(21)22)7-12(9-13)17(23)24/h1-9H,(H,21,22)(H,23,24)/b14-6-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168889 (3-Methyl-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-...) Show SMILES Cc1cc(ccc1N1C(=S)S\C(=C/c2ccccc2)C1=O)C(O)=O Show InChI InChI=1S/C18H13NO3S2/c1-11-9-13(17(21)22)7-8-14(11)19-16(20)15(24-18(19)23)10-12-5-3-2-4-6-12/h2-10H,1H3,(H,21,22)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168892 (4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES COC(=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C18H13NO3S2/c1-22-17(21)13-7-9-14(10-8-13)19-16(20)15(24-18(19)23)11-12-5-3-2-4-6-12/h2-11H,1H3/b15-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168886 (4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...) Show SMILES OS(=O)(=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C16H11NO4S3/c18-15-14(10-11-4-2-1-3-5-11)23-16(22)17(15)12-6-8-13(9-7-12)24(19,20)21/h1-10H,(H,19,20,21)/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168891 (4-{4-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-5-oxo-...) Show SMILES OC(=O)c1ccc(cc1)N1C(=S)NC(=Cc2ccc(F)cc2)C1=O |w:14.15| Show InChI InChI=1S/C17H11FN2O3S/c18-12-5-1-10(2-6-12)9-14-15(21)20(17(24)19-14)13-7-3-11(4-8-13)16(22)23/h1-9H,(H,19,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168893 (3-{5-[1-Cyclohexyl-meth-(Z)-ylidene]-4-oxo-2-thiox...) Show SMILES OC(=O)c1cccc(c1)N1C(=S)S\C(=C/C2CCCCC2)C1=O Show InChI InChI=1S/C17H17NO3S2/c19-15-14(9-11-5-2-1-3-6-11)23-17(22)18(15)13-8-4-7-12(10-13)16(20)21/h4,7-11H,1-3,5-6H2,(H,20,21)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168882 (2-Hydroxy-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...) Show SMILES OC(=O)c1ccc(cc1O)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C17H11NO4S2/c19-13-9-11(6-7-12(13)16(21)22)18-15(20)14(24-17(18)23)8-10-4-2-1-3-5-10/h1-9,19H,(H,21,22)/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168894 ((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...) Show SMILES OP(O)(=O)Cc1ccc(cc1)N1C(=S)SC(=Cc2ccccc2)C1=O |w:16.17| Show InChI InChI=1S/C17H14NO4PS2/c19-16-15(10-12-4-2-1-3-5-12)25-17(24)18(16)14-8-6-13(7-9-14)11-23(20,21)22/h1-10H,11H2,(H2,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168897 (3-{5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo...) Show SMILES COc1ccc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C18H13NO4S2/c1-23-14-7-5-11(6-8-14)9-15-16(20)19(18(24)25-15)13-4-2-3-12(10-13)17(21)22/h2-10H,1H3,(H,21,22)/b15-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168883 ((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...) Show SMILES OC(=O)Cc1ccc(cc1)N1C(=S)S\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C18H13NO3S2/c20-16(21)11-13-6-8-14(9-7-13)19-17(22)15(24-18(19)23)10-12-4-2-1-3-5-12/h1-10H,11H2,(H,20,21)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168895 (3-[(5Z)-5-(4-carboxybenzylidene)-4-oxo-2-thioxo-1,...) Show SMILES OC(=O)c1ccc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C18H11NO5S2/c20-15-14(8-10-4-6-11(7-5-10)16(21)22)26-18(25)19(15)13-3-1-2-12(9-13)17(23)24/h1-9H,(H,21,22)(H,23,24)/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168898 (3-{5-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-4-oxo...) Show SMILES OC(=O)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(O)cc2)C1=O Show InChI InChI=1S/C17H11NO4S2/c19-13-6-4-10(5-7-13)8-14-15(20)18(17(23)24-14)12-3-1-2-11(9-12)16(21)22/h1-9,19H,(H,21,22)/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168896 (4-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...) Show SMILES OC(=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(F)cc2)C1=O Show InChI InChI=1S/C17H10FNO3S2/c18-12-5-1-10(2-6-12)9-14-15(20)19(17(23)24-14)13-7-3-11(4-8-13)16(21)22/h1-9H,(H,21,22)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50168899 (4-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2,4-di...) Show SMILES OC(=O)c1ccc(cc1)N1C(=O)S\C(=C/c2ccc(F)cc2)C1=O Show InChI InChI=1S/C17H10FNO4S/c18-12-5-1-10(2-6-12)9-14-15(20)19(17(23)24-14)13-7-3-11(4-8-13)16(21)22/h1-9H,(H,21,22)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ceptyr Inc. Curated by ChEMBL					Assay Description Inhibition of JNK-stimulating phosphatase-1 (JSP-1)				Bioorg Med Chem Lett 15: 3374-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.034 BindingDB Entry DOI: 10.7270/Q2NG4Q4B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM82577 ((4-fluoro-1,3-benzothiazol-2-yl)-[5-(4-methoxyphen...) Show SMILES COc1ccc(cc1)-c1nnc(Nc2nc3c(F)cccc3s2)o1 Show InChI InChI=1S/C16H11FN4O2S/c1-22-10-7-5-9(6-8-10)14-20-21-15(23-14)19-16-18-13-11(17)3-2-4-12(13)24-16/h2-8H,1H3,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant VHX (unknown origin) using OMFP as substrate after 1 hr by fluorescence assay				Bioorg Med Chem 23: 2786-97 (2015) Article DOI: 10.1016/j.bmc.2015.03.075 BindingDB Entry DOI: 10.7270/Q2BG2QQD
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205419 (CHEMBL230472 | N3-butyl-N1-(2,3-di(furan-2-yl)quin...) Show SMILES CCCCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:9.8| Show InChI InChI=1S/C29H33N5O4/c1-3-5-14-33(4-2)28(35)20-9-6-15-34(19-20)29(36)30-21-12-13-22-23(18-21)32-27(25-11-8-17-38-25)26(31-22)24-10-7-16-37-24/h7-8,10-13,16-18,20H,3-6,9,14-15,19H2,1-2H3,(H,30,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205420 (CHEMBL230363 | N-(2,3-dimethoxyquinoxalin-6-yl)-3-...) Show SMILES COc1nc2ccc(NC(=O)N3CCCC(C3)C(=O)N3CCCCC3)cc2nc1OC |w:15.17| Show InChI InChI=1S/C22H29N5O4/c1-30-19-20(31-2)25-18-13-16(8-9-17(18)24-19)23-22(29)27-12-6-7-15(14-27)21(28)26-10-4-3-5-11-26/h8-9,13,15H,3-7,10-12,14H2,1-2H3,(H,23,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205422 (CHEMBL230941 | N3-cyclohexyl-N1-(2,3-di(furan-2-yl...) Show SMILES O=C(NC1CCCCC1)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:9.9| Show InChI InChI=1S/C29H31N5O4/c35-28(30-20-8-2-1-3-9-20)19-7-4-14-34(18-19)29(36)31-21-12-13-22-23(17-21)33-27(25-11-6-16-38-25)26(32-22)24-10-5-15-37-24/h5-6,10-13,15-17,19-20H,1-4,7-9,14,18H2,(H,30,35)(H,31,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205421 (CHEMBL395086 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...) Show SMILES CCNC(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:5.4| Show InChI InChI=1S/C25H25N5O4/c1-2-26-24(31)16-6-3-11-30(15-16)25(32)27-17-9-10-18-19(14-17)29-23(21-8-5-13-34-21)22(28-18)20-7-4-12-33-20/h4-5,7-10,12-14,16H,2-3,6,11,15H2,1H3,(H,26,31)(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205423 (CHEMBL230093 | N3-cyclopentyl-N1-(2,3-dip-tolylqui...) Show SMILES Cc1ccc(cc1)-c1nc2ccc(NC(=O)N3CCCC(C3)C(=O)NC3CCCC3)cc2nc1-c1ccc(C)cc1 |w:20.23| Show InChI InChI=1S/C34H37N5O2/c1-22-9-13-24(14-10-22)31-32(25-15-11-23(2)12-16-25)38-30-20-28(17-18-29(30)37-31)36-34(41)39-19-5-6-26(21-39)33(40)35-27-7-3-4-8-27/h9-18,20,26-27H,3-8,19,21H2,1-2H3,(H,35,40)(H,36,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205424 (CHEMBL230258 | N1-(2,3-bis(4-fluorophenyl)quinoxal...) Show SMILES Fc1ccc(cc1)-c1nc2ccc(NC(=O)N3CCCC(C3)C(=O)NC3CCCCC3)cc2nc1-c1ccc(F)cc1 |w:20.23| Show InChI InChI=1S/C33H33F2N5O2/c34-24-12-8-21(9-13-24)30-31(22-10-14-25(35)15-11-22)39-29-19-27(16-17-28(29)38-30)37-33(42)40-18-4-5-23(20-40)32(41)36-26-6-2-1-3-7-26/h8-17,19,23,26H,1-7,18,20H2,(H,36,41)(H,37,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205426 (CHEMBL230843 | N3-cyclopentyl-N1-(2,3-di(furan-2-y...) Show SMILES O=C(NC1CCCC1)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:8.8| Show InChI InChI=1S/C28H29N5O4/c34-27(29-19-7-1-2-8-19)18-6-3-13-33(17-18)28(35)30-20-11-12-21-22(16-20)32-26(24-10-5-15-37-24)25(31-21)23-9-4-14-36-23/h4-5,9-12,14-16,18-19H,1-3,6-8,13,17H2,(H,29,34)(H,30,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205425 (CHEMBL230842 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:7.6| Show InChI InChI=1S/C27H29N5O4/c1-3-31(4-2)26(33)18-8-5-13-32(17-18)27(34)28-19-11-12-20-21(16-19)30-25(23-10-7-15-36-23)24(29-20)22-9-6-14-35-22/h6-7,9-12,14-16,18H,3-5,8,13,17H2,1-2H3,(H,28,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205427 (CHEMBL230681 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...) Show SMILES CC(C)CNC(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:7.6| Show InChI InChI=1S/C27H29N5O4/c1-17(2)15-28-26(33)18-6-3-11-32(16-18)27(34)29-19-9-10-20-21(14-19)31-25(23-8-5-13-36-23)24(30-20)22-7-4-12-35-22/h4-5,7-10,12-14,17-18H,3,6,11,15-16H2,1-2H3,(H,28,33)(H,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205428 (CHEMBL230471 | N3-butyl-N1-(2,3-di(furan-2-yl)quin...) Show SMILES CCCCN(C)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:8.7| Show InChI InChI=1S/C28H31N5O4/c1-3-4-13-32(2)27(34)19-8-5-14-33(18-19)28(35)29-20-11-12-21-22(17-20)31-26(24-10-7-16-37-24)25(30-21)23-9-6-15-36-23/h6-7,9-12,15-17,19H,3-5,8,13-14,18H2,1-2H3,(H,29,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205430 (CHEMBL397726 | N1-(2,3-bis(4-bromophenyl)quinoxali...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccc(Br)cc3)c(nc2c1)-c1ccc(Br)cc1 |w:7.6| Show InChI InChI=1S/C31H31Br2N5O2/c1-3-37(4-2)30(39)22-6-5-17-38(19-22)31(40)34-25-15-16-26-27(18-25)36-29(21-9-13-24(33)14-10-21)28(35-26)20-7-11-23(32)12-8-20/h7-16,18,22H,3-6,17,19H2,1-2H3,(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205429 (CHEMBL425838 | N3-tert-butyl-N1-(2,3-di(furan-2-yl...) Show SMILES CC(C)(C)NC(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:7.6| Show InChI InChI=1S/C27H29N5O4/c1-27(2,3)31-25(33)17-7-4-12-32(16-17)26(34)28-18-10-11-19-20(15-18)30-24(22-9-6-14-36-22)23(29-19)21-8-5-13-35-21/h5-6,8-11,13-15,17H,4,7,12,16H2,1-3H3,(H,28,34)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205431 (CHEMBL230206 | N1-(2,3-diphenylquinoxalin-6-yl)-N3...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccccc1 |w:7.6| Show InChI InChI=1S/C31H33N5O2/c1-3-35(4-2)30(37)24-16-11-19-36(21-24)31(38)32-25-17-18-26-27(20-25)34-29(23-14-9-6-10-15-23)28(33-26)22-12-7-5-8-13-22/h5-10,12-15,17-18,20,24H,3-4,11,16,19,21H2,1-2H3,(H,32,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205432 (CHEMBL446453 | N-(2,3-di(furan-2-yl)quinoxalin-6-y...) Show SMILES O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCCC(C1)C(=O)N1CCCCC1 |w:27.33| Show InChI InChI=1S/C28H29N5O4/c34-27(32-12-2-1-3-13-32)19-7-4-14-33(18-19)28(35)29-20-10-11-21-22(17-20)31-26(24-9-6-16-37-24)25(30-21)23-8-5-15-36-23/h5-6,8-11,15-17,19H,1-4,7,12-14,18H2,(H,29,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205434 (CHEMBL230207 | N1-(2,3-dip-tolylquinoxalin-6-yl)-N...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccc(C)cc3)c(nc2c1)-c1ccc(C)cc1 |w:7.6| Show InChI InChI=1S/C33H37N5O2/c1-5-37(6-2)32(39)26-8-7-19-38(21-26)33(40)34-27-17-18-28-29(20-27)36-31(25-15-11-23(4)12-16-25)30(35-28)24-13-9-22(3)10-14-24/h9-18,20,26H,5-8,19,21H2,1-4H3,(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205433 (CHEMBL230577 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...) Show SMILES CC(C)NC(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |w:6.5| Show InChI InChI=1S/C26H27N5O4/c1-16(2)27-25(32)17-6-3-11-31(15-17)26(33)28-18-9-10-19-20(14-18)30-24(22-8-5-13-35-22)23(29-19)21-7-4-12-34-21/h4-5,7-10,12-14,16-17H,3,6,11,15H2,1-2H3,(H,27,32)(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205437 (CHEMBL439875 | N1-(2,3-bis(4-fluorophenyl)quinoxal...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)Nc1ccc2nc(-c3ccc(F)cc3)c(nc2c1)-c1ccc(F)cc1 |w:7.6| Show InChI InChI=1S/C31H31F2N5O2/c1-3-37(4-2)30(39)22-6-5-17-38(19-22)31(40)34-25-15-16-26-27(18-25)36-29(21-9-13-24(33)14-10-21)28(35-26)20-7-11-23(32)12-8-20/h7-16,18,22H,3-6,17,19H2,1-2H3,(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50205436 (CHEMBL230362 | N-(2,3-bis(4-bromophenyl)quinoxalin...) Show SMILES Brc1ccc(cc1)-c1nc2ccc(NC(=O)N3CCCC(C3)C(=O)N3CCCC3)cc2nc1-c1ccc(Br)cc1 |w:20.23| Show InChI InChI=1S/C31H29Br2N5O2/c32-23-9-5-20(6-10-23)28-29(21-7-11-24(33)12-8-21)36-27-18-25(13-14-26(27)35-28)34-31(40)38-17-3-4-22(19-38)30(39)37-15-1-2-16-37/h5-14,18,22H,1-4,15-17,19H2,(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant JSP1				Bioorg Med Chem Lett 17: 2118-22 (2007) Article DOI: 10.1016/j.bmcl.2007.01.094 BindingDB Entry DOI: 10.7270/Q2R49QFR
					More data for this Ligand-Target Pair

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