Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'General receptor of phosphoinositides 1 (GRP1)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytohesin-3 (Homo sapiens (Human))	BDBM112784 (US8628961, PIT-1) Show SMILES Oc1c(Cl)cc(cc1NC(=S)NC(=O)c1ccccc1)[N+]([O-])=O Show InChI InChI=1S/C14H10ClN3O4S/c15-10-6-9(18(21)22)7-11(12(10)19)16-14(23)17-13(20)8-4-2-1-3-5-8/h1-7,19H,(H2,16,17,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.03E+4	n/a	n/a	n/a	n/a	7.5	25
Tufts University; Council of Scientific and Industrial Research US Patent					Assay Description In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...				US Patent US8628961 (2014) BindingDB Entry DOI: 10.7270/Q2MG7N5S
					More data for this Ligand-Target Pair
Cytohesin-3 (Homo sapiens (Human))	BDBM112785 (US8628961, DM-PIT-1) Show SMILES Cc1cc(C)cc(c1)C(=O)NC(=S)Nc1cc(ccc1O)[N+]([O-])=O Show InChI InChI=1S/C16H15N3O4S/c1-9-5-10(2)7-11(6-9)15(21)18-16(24)17-13-8-12(19(22)23)3-4-14(13)20/h3-8,20H,1-2H3,(H2,17,18,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a	7.5	25
Tufts University; Council of Scientific and Industrial Research US Patent					Assay Description In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...				US Patent US8628961 (2014) BindingDB Entry DOI: 10.7270/Q2MG7N5S
					More data for this Ligand-Target Pair
Cytohesin-3 (Homo sapiens (Human))	BDBM50013327 (CHEMBL3263343) Show SMILES OC(=O)c1cc(n[nH]1)P(O)(O)=O Show InChI InChI=1S/C4H5N2O5P/c7-4(8)2-1-3(6-5-2)12(9,10)11/h1H,(H,5,6)(H,7,8)(H2,9,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal 6xHis-tagged Grp1 PH domain (unknown origin) expressed in Escherichia coli BL21(DE3) RIL assessed as inhibition ...				Bioorg Med Chem Lett 24: 2256-62 (2014) Article DOI: 10.1016/j.bmcl.2014.03.085 BindingDB Entry DOI: 10.7270/Q2NP25ZS
					More data for this Ligand-Target Pair