Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 7 (HDAC7)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 5 of Histone deacetylase 7 (5) 18-991] (Homo sapiens (Human))	BDBM50207561 (CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...) Show SMILES ONC(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H13NO2/c16-14(15-17)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13,17H,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	354	n/a	n/a	n/a	n/a	8.0	n/a
University of Queensland					Assay Description Fluorescence readings were carried out on a CytofluorR Series 4000 fluorescence multiwell plate reader (Perspective Biosystems). Stock solutions of t...				J Biol Chem 288: 25362-74 (2013) Article DOI: 10.1074/jbc.M113.496281 BindingDB Entry DOI: 10.7270/Q2JS9P97
					More data for this Ligand-Target Pair
Histone deacetylase 7 [518-592] (Homo sapiens (Human))	BDBM50446481 (CHEMBL3110004 | US10011611, TMP269 | US10722597, C...) Show SMILES FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University					Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...				Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 7 [518-592] (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University					Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...				Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 7 [518-592] (Homo sapiens (Human))	BDBM402284 ((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...) Show SMILES ONC(=O)c1ccc(Cn2sc3ncccc3c2=O)cc1 Show InChI InChI=1S/C14H11N3O3S/c18-12(16-20)10-5-3-9(4-6-10)8-17-14(19)11-2-1-7-15-13(11)21-17/h1-7,20H,8H2,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University					Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...				Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0
					More data for this Ligand-Target Pair
Histone deacetylase 7 [518-592] (Homo sapiens (Human))	BDBM50005711 (CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...) Show SMILES C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	4.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University					Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...				Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0
					More data for this Ligand-Target Pair				3D Structure (crystal)