Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97666 (US8476295, 1.1.04) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97665 (US8476295, 1.1.03) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 59 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97663 (US8476295, 1.1.01) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 72 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97664 (US8476295, 1.1.02) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 91 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97667 (US8476295, 2.1.01) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 806 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM97668 (US8476295, 3.1.01) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 976 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM362931 (US9849138, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of Michigan US Patent | Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE... | US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM362925 (US9849138, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of Michigan US Patent | Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE... | US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM362926 (US9849138, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of Michigan US Patent | Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE... | US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM362928 (US9849138, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of Michigan US Patent | Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE... | US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human)) | BDBM362930 (US9849138, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of Michigan US Patent | Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE... | US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95 | |||||||||||
More data for this Ligand-Target Pair |